U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

PRRC2B proline rich coiled-coil 2B [ Homo sapiens (human) ]

Gene ID: 84726, updated on 13-May-2022

Summary

Official Symbol
PRRC2Bprovided by HGNC
Official Full Name
proline rich coiled-coil 2Bprovided by HGNC
Primary source
HGNC:HGNC:28121
See related
Ensembl:ENSG00000288701 MIM:619544; AllianceGenome:HGNC:28121
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
BAT2L; BAT2L1; LQFBS-1; KIAA0515
Summary
Enables RNA binding activity. Predicted to be involved in cell differentiation. Predicted to act upstream of or within in utero embryonic development. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in brain (RPKM 18.3), ovary (RPKM 17.4) and 25 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See PRRC2B in Genome Data Viewer
Location:
9q34.13
Exon count:
33
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (131373651..131500193)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (143583138..143713087)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (134249038..134375580)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 12946 Neighboring gene phospholipid phosphatase 7 (inactive) Neighboring gene uncharacterized LOC105376299 Neighboring gene uncharacterized LOC105376300 Neighboring gene Sharpr-MPRA regulatory region 9532 Neighboring gene small nucleolar RNA, C/D box 62A Neighboring gene uncharacterized LOC124902290 Neighboring gene small nucleolar RNA, C/D box 62B Neighboring gene uncharacterized LOC105376301 Neighboring gene protein O-mannosyltransferase 1 Neighboring gene uridine-cytidine kinase 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA0515, MGC10526, DKFZp781F05101, DKFZp781K12107

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables RNA binding HDA PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
protein PRRC2B
Names
HLA-B associated transcript 2-like
HLA-B-associated transcript 2-like 1
proline-rich coiled-coil protein 2B
protein BAT2-like 1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001384818.1NP_001371747.1  protein PRRC2B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL354855, AL358781
    Related
    ENSP00000508005.1, ENST00000684596.1
    Conserved Domains (2) summary
    pfam03154
    Location:18662175
    Atrophin-1; Atrophin-1 family
    pfam07001
    Location:1189
    BAT2_N; BAT2 N-terminus
  2. NM_001384821.1NP_001371750.1  protein PRRC2B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL354855, AL358781
    Conserved Domains (2) summary
    pfam03154
    Location:18652174
    Atrophin-1; Atrophin-1 family
    pfam07001
    Location:1189
    BAT2_N; BAT2 N-terminus
  3. NM_001384822.1NP_001371751.1  protein PRRC2B isoform 3

    Status: VALIDATED

    Source sequence(s)
    AL354855, AL358781
    Conserved Domains (2) summary
    pfam03154
    Location:18652154
    Atrophin-1; Atrophin-1 family
    pfam07001
    Location:1189
    BAT2_N; BAT2 N-terminus
  4. NM_001384823.1NP_001371752.1  protein PRRC2B isoform 4

    Status: VALIDATED

    Source sequence(s)
    AL354855, AL358781
    Related
    ENSP00000508073.1, ENST00000682501.1
    Conserved Domains (1) summary
    pfam07001
    Location:1189
    BAT2_N; BAT2 N-terminus
  5. NM_013318.4NP_037450.2  protein PRRC2B isoform 1

    See identical proteins and their annotated locations for NP_037450.2

    Status: VALIDATED

    Source sequence(s)
    AL354855, AL358781
    Consensus CDS
    CCDS48044.1
    UniProtKB/Swiss-Prot
    Q5JSZ5
    UniProtKB/TrEMBL
    Q9BU62
    Related
    ENSP00000508048.1, ENST00000683519.1
    Conserved Domains (2) summary
    pfam03154
    Location:18662175
    Atrophin-1; Atrophin-1 family
    pfam07001
    Location:1189
    BAT2_N; BAT2 N-terminus

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

    Range
    131373651..131500193
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060933.1 Alternate T2T-CHM13v2.0

    Range
    143583138..143713087
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_032640.2: Suppressed sequence

    Description
    NM_032640.2: This RefSeq was suppressed temporarily based on the calculation that the annotated protein was shorter than a protein or proteins from a putative ortholog.