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SPATA22 spermatogenesis associated 22 [ Homo sapiens (human) ]

Gene ID: 84690, updated on 22-Aug-2020

Summary

Official Symbol
SPATA22provided by HGNC
Official Full Name
spermatogenesis associated 22provided by HGNC
Primary source
HGNC:HGNC:30705
See related
Ensembl:ENSG00000141255 MIM:617673
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
NYDSP20; NYD-SP20
Expression
Restricted expression toward testis (RPKM 73.6) See more
Orthologs

Genomic context

See SPATA22 in Genome Data Viewer
Location:
17p13.2
Exon count:
10
Annotation release Status Assembly Chr Location
109.20200815 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (3440019..3513858, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (3343305..3417146, complement)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 3 subfamily A member 3 Neighboring gene olfactory receptor family 1 subfamily E member 2 Neighboring gene aspartoacylase Neighboring gene transient receptor potential cation channel subfamily V member 3 Neighboring gene transient receptor potential cation channel subfamily V member 1 Neighboring gene pterin-4 alpha-carbinolamine dehydratase 2 pseudogene Neighboring gene sedoheptulokinase

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
A genome-wide association study provides evidence for association of chromosome 8p23 (MYP10) and 10q21.1 (MYP15) with high myopia in the French Population.
GeneReviews: Not available

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
gamete generation IEA
Inferred from Electronic Annotation
more info
 
meiotic DNA repair synthesis IEA
Inferred from Electronic Annotation
more info
 
regulation of meiotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
synapsis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
chromosome IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
spermatogenesis-associated protein 22
Names
testicular tissue protein Li 186
testis development protein NYD-SP20

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001170695.2NP_001164166.1  spermatogenesis-associated protein 22 isoform 2

    See identical proteins and their annotated locations for NP_001164166.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR and contains an alternate exon which results in a frameshift, compared to variant 1. The resulting protein (isoform 2) is longer and has a distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AC025125, BC029483, BG716998
    Consensus CDS
    CCDS11027.1
    UniProtKB/Swiss-Prot
    Q8NHS9
    UniProtKB/TrEMBL
    A0A140VJV9
    Related
    ENSP00000459329.1, ENST00000575375.5
  2. NM_001170696.2NP_001164167.1  spermatogenesis-associated protein 22 isoform 3

    See identical proteins and their annotated locations for NP_001164167.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR and has multiple coding region differences, compared to variant 1, one of which results in a frameshift. The resulting protein (isoform 3) has a distinct C-terminus and is longer than isoform 1.
    Source sequence(s)
    AC025125, AY032684, BG716998
    Consensus CDS
    CCDS54066.1
    UniProtKB/Swiss-Prot
    Q8NHS9
    Related
    ENSP00000347541.4, ENST00000355380.8
  3. NM_001170697.2NP_001164168.1  spermatogenesis-associated protein 22 isoform 2

    See identical proteins and their annotated locations for NP_001164168.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR and contains an alternate exon which results in a frameshift, compared to variant 1. The resulting protein (isoform 2) is longer and has a distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AC025125, AF367472, BP371122
    Consensus CDS
    CCDS11027.1
    UniProtKB/Swiss-Prot
    Q8NHS9
    UniProtKB/TrEMBL
    A0A140VJV9
    Related
    ENSP00000459580.1, ENST00000573128.5
  4. NM_001170698.2NP_001164169.1  spermatogenesis-associated protein 22 isoform 2

    See identical proteins and their annotated locations for NP_001164169.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and contains an alternate exon which results in a frameshift, compared to variant 1. The resulting protein (isoform 2) is longer and has a distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AC025125, AY035867, BI463957
    Consensus CDS
    CCDS11027.1
    UniProtKB/Swiss-Prot
    Q8NHS9
    UniProtKB/TrEMBL
    A0A140VJV9
    Related
    ENSP00000460187.1, ENST00000572969.5
  5. NM_001170699.2NP_001164170.1  spermatogenesis-associated protein 22 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the shortest isoform (1).
    Source sequence(s)
    AC025125, AK301892, BC029483, DB450733
    Consensus CDS
    CCDS54067.1
    UniProtKB/Swiss-Prot
    Q8NHS9
    Related
    ENSP00000268981.5, ENST00000268981.9
  6. NM_001321336.2NP_001308265.1  spermatogenesis-associated protein 22 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC025125, AK295299, AY035868, BC029483
    Consensus CDS
    CCDS82036.1
    UniProtKB/Swiss-Prot
    Q8NHS9
    UniProtKB/TrEMBL
    B4DHW8, F5GWB9
    Related
    ENSP00000441920.1, ENST00000541913.5
  7. NM_001321337.2NP_001308266.1  spermatogenesis-associated protein 22 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC025125, AK295299, AY035868, BC029483
    Consensus CDS
    CCDS11027.1
    UniProtKB/Swiss-Prot
    Q8NHS9
    UniProtKB/TrEMBL
    A0A140VJV9, B4DHW8
  8. NM_032598.5NP_115987.2  spermatogenesis-associated protein 22 isoform 2

    See identical proteins and their annotated locations for NP_115987.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and contains an alternate exon which results in a frameshift, compared to variant 1. The resulting protein (isoform 2) is longer and has a distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AC025125, AY035868
    Consensus CDS
    CCDS11027.1
    UniProtKB/Swiss-Prot
    Q8NHS9
    UniProtKB/TrEMBL
    A0A140VJV9
    Related
    ENSP00000380354.3, ENST00000397168.7

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20200815

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

    Range
    3440019..3513858 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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