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ZNF347 zinc finger protein 347 [ Homo sapiens (human) ]

Gene ID: 84671, updated on 1-Jun-2020

Summary

Official Symbol
ZNF347provided by HGNC
Official Full Name
zinc finger protein 347provided by HGNC
Primary source
HGNC:HGNC:16447
See related
Ensembl:ENSG00000197937
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ZNF1111
Expression
Ubiquitous expression in spleen (RPKM 2.5), thyroid (RPKM 2.3) and 25 other tissues See more
Orthologs

Genomic context

See ZNF347 in Genome Data Viewer
Location:
19q13.42
Exon count:
5
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (53134935..53159060, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (53641553..53662322, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene zinc finger protein 160 Neighboring gene zinc finger protein 415 Neighboring gene Sharpr-MPRA regulatory region 171 Neighboring gene zinc finger protein 665 Neighboring gene zinc finger protein 415 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
zinc finger protein 347
Names
CTD-2620I22.7
zinc finger 1111
zinc finger protein 1111

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001172674.1NP_001166145.1  zinc finger protein 347 isoform a

    See identical proteins and their annotated locations for NP_001166145.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. Both variants 1 and 2 encode the same isoform (a), which is longer than isoform b.
    Source sequence(s)
    AA978292, AC010328, AK096623
    Consensus CDS
    CCDS54314.1
    UniProtKB/Swiss-Prot
    Q96SE7
    UniProtKB/TrEMBL
    A0A024R4L7
    Related
    ENSP00000405218.2, ENST00000452676.6
    Conserved Domains (6) summary
    smart00349
    Location:867
    KRAB; krueppel associated box
    COG5048
    Location:273728
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:460480
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:458480
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:847
    KRAB; KRAB box
    pfam13465
    Location:333357
    zf-H2C2_2; Zinc-finger double domain
  2. NM_001172675.2NP_001166146.1  zinc finger protein 347 isoform a

    See identical proteins and their annotated locations for NP_001166146.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Both variants 1 and 2 encode the same isoform (a), which is longer than isoform b.
    Source sequence(s)
    AA776564, AA978292, AC010328, AI366675, AK289994, AY029765, DB316074
    Consensus CDS
    CCDS54314.1
    UniProtKB/Swiss-Prot
    Q96SE7
    UniProtKB/TrEMBL
    A0A024R4L7, A8K1S9
    Related
    ENSP00000471712.2, ENST00000601469.2
    Conserved Domains (6) summary
    smart00349
    Location:867
    KRAB; krueppel associated box
    COG5048
    Location:273728
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:460480
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:458480
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:847
    KRAB; KRAB box
    pfam13465
    Location:333357
    zf-H2C2_2; Zinc-finger double domain
  3. NM_032584.3NP_115973.2  zinc finger protein 347 isoform b

    See identical proteins and their annotated locations for NP_115973.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and uses an alternate in-frame splice site in the coding region, compared to variant 1. The resulting isoform (b) lacks one internal amino acid, compared to isoform a.
    Source sequence(s)
    AA776564, AA978292, AC010328, AI366675, AY029765, DB214217, DB316074
    Consensus CDS
    CCDS33097.1
    UniProtKB/Swiss-Prot
    Q96SE7
    Related
    ENSP00000334146.6, ENST00000334197.11
    Conserved Domains (6) summary
    smart00349
    Location:866
    KRAB; krueppel associated box
    COG5048
    Location:272727
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:459479
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:457479
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:847
    KRAB; KRAB box
    pfam13465
    Location:332356
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    53134935..53159060 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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