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KIF2B kinesin family member 2B [ Homo sapiens (human) ]

Gene ID: 84643, updated on 4-Jun-2020

Summary

Official Symbol
KIF2Bprovided by HGNC
Official Full Name
kinesin family member 2Bprovided by HGNC
Primary source
HGNC:HGNC:29443
See related
Ensembl:ENSG00000141200 MIM:615142
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Orthologs

Genomic context

See KIF2B in Genome Data Viewer
Location:
17q22
Exon count:
1
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (53822927..53825193)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (51900239..51902573)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107984982 Neighboring gene ribosomal protein S2 pseudogene 48 Neighboring gene zinc finger protein 816A pseudogene Neighboring gene uncharacterized LOC107985001

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

HIV-1 interactions

Replication interactions

Interaction Pubs
Knockdown of kinesin family member 2B (KIF2B) by siRNA inhibits HIV-1 replication in HeLa P4/R5 cells PubMed

Go to the HIV-1, Human Interaction Database

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • FLJ53902

Gene Ontology Provided by GOA

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
ATPase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
microtubule binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
microtubule motor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
antigen processing and presentation of exogenous peptide antigen via MHC class II TAS
Traceable Author Statement
more info
 
cell division IEA
Inferred from Electronic Annotation
more info
 
metaphase plate congression IMP
Inferred from Mutant Phenotype
more info
PubMed 
microtubule depolymerization IMP
Inferred from Mutant Phenotype
more info
PubMed 
microtubule depolymerization TAS
Traceable Author Statement
more info
PubMed 
microtubule-based movement IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
microtubule-based movement TAS
Traceable Author Statement
more info
 
regulation of chromosome segregation IMP
Inferred from Mutant Phenotype
more info
PubMed 
retrograde vesicle-mediated transport, Golgi to ER TAS
Traceable Author Statement
more info
 
Component Evidence Code Pubs
centrosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
condensed chromosome kinetochore IEA
Inferred from Electronic Annotation
more info
 
cytosol TAS
Traceable Author Statement
more info
 
intercellular bridge IDA
Inferred from Direct Assay
more info
 
kinesin complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
microtubule IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
microtubule cytoskeleton IDA
Inferred from Direct Assay
more info
 
mitotic spindle IDA
Inferred from Direct Assay
more info
 
nucleolus IDA
Inferred from Direct Assay
more info
 
spindle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
kinesin-like protein KIF2B
Names
kinesin protein
testis tissue sperm-binding protein Li 82P

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_032559.5NP_115948.4  kinesin-like protein KIF2B

    See identical proteins and their annotated locations for NP_115948.4

    Status: VALIDATED

    Source sequence(s)
    AC019315, AF333335
    Consensus CDS
    CCDS32685.1
    UniProtKB/Swiss-Prot
    Q8N4N8
    UniProtKB/TrEMBL
    A0A140VKG5
    Related
    ENSP00000268919.4, ENST00000268919.6
    Conserved Domains (2) summary
    cd01367
    Location:213541
    KISc_KIF2_like; Kinesin motor domain, KIF2-like group
    pfam00225
    Location:219541
    Kinesin; Kinesin motor domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

    Range
    53822927..53825193
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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