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KRBA1 KRAB-A domain containing 1 [ Homo sapiens (human) ]

Gene ID: 84626, updated on 26-Oct-2022

Summary

Official Symbol
KRBA1provided by HGNC
Official Full Name
KRAB-A domain containing 1provided by HGNC
Primary source
HGNC:HGNC:22228
See related
Ensembl:ENSG00000133619 AllianceGenome:HGNC:22228
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to be involved in regulation of transcription, DNA-templated. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in heart (RPKM 3.8), ovary (RPKM 2.4) and 24 other tissues See more
Orthologs
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Genomic context

See KRBA1 in Genome Data Viewer
Location:
7q36.1
Exon count:
19
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (149714951..149734575)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (150896867..150916494)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (149412042..149431664)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene tRNA-Cys (anticodon GCA) 9-4 Neighboring gene Sharpr-MPRA regulatory region 9729 Neighboring gene uncharacterized LOC124901771 Neighboring gene zinc finger protein 467 Neighboring gene SCO-spondin, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA1862, MGC176633

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_029620.2 RefSeqGene

    Range
    5002..24626
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001290187.2NP_001277116.1  protein KRBA1 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) encodes the longer isoform (2).
    Source sequence(s)
    AC004897, AL831935, BC142722, BC150330
    Consensus CDS
    CCDS78285.1
    UniProtKB/Swiss-Prot
    A5PL33
    UniProtKB/TrEMBL
    A0A0C4DH65
    Related
    ENSP00000418647.3, ENST00000496259.6
    Conserved Domains (3) summary
    smart00349
    Location:864
    KRAB; krueppel associated box
    pfam01352
    Location:846
    KRAB; KRAB box
    pfam15287
    Location:229271
    KRBA1; KRBA1 family repeat
  2. NM_001394478.1NP_001381407.1  protein KRBA1 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC004897, KF459639
    Conserved Domains (2) summary
    cd07765
    Location:745
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
    PHA03247
    Location:128573
    PHA03247; large tegument protein UL36; Provisional
  3. NM_001394479.1NP_001381408.1  protein KRBA1 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC004897, KF459639
    Conserved Domains (1) summary
    cd07765
    Location:745
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
  4. NM_001394480.1NP_001381409.1  protein KRBA1 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC004897, KF459639
    Conserved Domains (1) summary
    cd07765
    Location:745
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
  5. NM_001394481.1NP_001381410.1  protein KRBA1 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC004897, KF459639
    Conserved Domains (2) summary
    cd07765
    Location:745
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
    PHA03247
    Location:113542
    PHA03247; large tegument protein UL36; Provisional
  6. NM_001394482.1NP_001381411.1  protein KRBA1 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AC004897, KF459639
    Conserved Domains (1) summary
    PHA03247
    Location:93522
    PHA03247; large tegument protein UL36; Provisional
  7. NM_001394483.1NP_001381412.1  protein KRBA1 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AC004897, KF459639
    Conserved Domains (1) summary
    PHA03247
    Location:93522
    PHA03247; large tegument protein UL36; Provisional
  8. NM_001394484.1NP_001381413.1  protein KRBA1 isoform 8

    Status: VALIDATED

    Source sequence(s)
    AC004897
    Conserved Domains (2) summary
    cd07765
    Location:745
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
    PHA03247
    Location:128586
    PHA03247; large tegument protein UL36; Provisional
  9. NM_001394485.1NP_001381414.1  protein KRBA1 isoform 9

    Status: VALIDATED

    Source sequence(s)
    AC004897
    Consensus CDS
    CCDS94228.1
    Related
    ENSP00000420112.2, ENST00000485033.6
    Conserved Domains (1) summary
    PHA03247
    Location:341803
    PHA03247; large tegument protein UL36; Provisional
  10. NM_001394486.1NP_001381415.1  protein KRBA1 isoform 10

    Status: VALIDATED

    Source sequence(s)
    AC004897, KF459639
    Conserved Domains (2) summary
    cd07765
    Location:745
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
    PHA03247
    Location:137558
    PHA03247; large tegument protein UL36; Provisional
  11. NM_001394487.1NP_001381416.1  protein KRBA1 isoform 11

    Status: VALIDATED

    Source sequence(s)
    AC004897, KF459639
    Conserved Domains (2) summary
    cd07765
    Location:745
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
    PHA03247
    Location:128557
    PHA03247; large tegument protein UL36; Provisional
  12. NM_001394488.1NP_001381417.1  protein KRBA1 isoform 12

    Status: VALIDATED

    Source sequence(s)
    AC004897, KF459639
    Conserved Domains (1) summary
    PHA03247
    Location:78507
    PHA03247; large tegument protein UL36; Provisional
  13. NM_001394489.1NP_001381418.1  protein KRBA1 isoform 13

    Status: VALIDATED

    Source sequence(s)
    AC004897
    Conserved Domains (2) summary
    cd07765
    Location:745
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
    PHA03247
    Location:123586
    PHA03247; large tegument protein UL36; Provisional
  14. NM_001394490.1NP_001381419.1  protein KRBA1 isoform 14

    Status: VALIDATED

    Source sequence(s)
    AC004897
    Related
    ENSP00000479341.1, ENST00000621069.1
    Conserved Domains (2) summary
    cd07765
    Location:745
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
    PHA03247
    Location:108571
    PHA03247; large tegument protein UL36; Provisional
  15. NM_001394491.1NP_001381420.1  protein KRBA1 isoform 17

    Status: VALIDATED

    Source sequence(s)
    AC004897, KF459639
    Conserved Domains (2) summary
    cd07765
    Location:4482
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
    PHA03247
    Location:150579
    PHA03247; large tegument protein UL36; Provisional
  16. NM_001394492.1NP_001381421.1  protein KRBA1 isoform 15

    Status: VALIDATED

    Source sequence(s)
    AC004897
  17. NM_001394493.1NP_001381422.1  protein KRBA1 isoform 16

    Status: VALIDATED

    Source sequence(s)
    AC004897
    Conserved Domains (1) summary
    cd07765
    Location:745
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
  18. NM_032534.4NP_115923.2  protein KRBA1 isoform 1

    See identical proteins and their annotated locations for NP_115923.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) differs in its 5' UTR and uses a downstream start codon, compared to variant 2. The encoded isoform (1) has a shorter N-terminus, compared to isoform 2.
    Source sequence(s)
    AB058765, AC004897, AL831935, BC142722, BC150330
    Consensus CDS
    CCDS75674.1
    UniProtKB/Swiss-Prot
    A5PL33, Q96JG5
    Related
    ENSP00000317165.9, ENST00000319551.12
    Conserved Domains (1) summary
    pfam15287
    Location:195237
    KRBA1; KRBA1 family repeat

RNA

  1. NR_172132.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC004897

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

    Range
    149714951..149734575
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047420964.1XP_047276920.1  protein KRBA1 isoform X1

  2. XM_047420969.1XP_047276925.1  protein KRBA1 isoform X6

  3. XM_047420965.1XP_047276921.1  protein KRBA1 isoform X2

  4. XM_047420970.1XP_047276926.1  protein KRBA1 isoform X7

  5. XM_047420966.1XP_047276922.1  protein KRBA1 isoform X3

  6. XM_047420967.1XP_047276923.1  protein KRBA1 isoform X4

  7. XM_047420968.1XP_047276924.1  protein KRBA1 isoform X5

    UniProtKB/Swiss-Prot
    Q96JG5
  8. XM_047420971.1XP_047276927.1  protein KRBA1 isoform X8

  9. XM_047420972.1XP_047276928.1  protein KRBA1 isoform X9

  10. XM_047420973.1XP_047276929.1  protein KRBA1 isoform X10

  11. XM_047420974.1XP_047276930.1  protein KRBA1 isoform X11

  12. XM_047420975.1XP_047276931.1  protein KRBA1 isoform X12

RNA

  1. XR_007060163.1 RNA Sequence

  2. XR_007060164.1 RNA Sequence

  3. XR_007060165.1 RNA Sequence

  4. XR_007060166.1 RNA Sequence

  5. XR_007060167.1 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060931.1 Alternate T2T-CHM13v2.0

    Range
    150896867..150916494
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)