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GON7 GON7 subunit of KEOPS complex [ Homo sapiens (human) ]

Gene ID: 84520, updated on 11-Jun-2021

Summary

Official Symbol
GON7provided by HGNC
Official Full Name
GON7 subunit of KEOPS complexprovided by HGNC
Primary source
HGNC:HGNC:20356
See related
Ensembl:ENSG00000170270 MIM:617436
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PNAS-127; C14orf142
Expression
Ubiquitous expression in colon (RPKM 9.4), kidney (RPKM 8.3) and 25 other tissues See more
Orthologs
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Genomic context

See GON7 in Genome Data Viewer
Location:
14q32.12
Exon count:
2
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 14 NC_000014.9 (93202894..93207065, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (93669239..93673410, complement)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene transmembrane protein 251 Neighboring gene modulator of apoptosis 1 Neighboring gene ubiquitin protein ligase E3 component n-recognin 7 Neighboring gene ribosomal protein L18a pseudogene 1 Neighboring gene BTB domain containing 7 Neighboring gene ribosomal protein L36a pseudogene 4

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC104244, MGC133207

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
part_of EKC/KEOPS complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of EKC/KEOPS complex IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
 
located_in nucleolus IDA
Inferred from Direct Assay
more info
 
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
EKC/KEOPS complex subunit GON7
Names
GON7, KEOPS complex subunit homolog
uncharacterized protein C14orf142

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_032490.5NP_115879.2  EKC/KEOPS complex subunit GON7

    See identical proteins and their annotated locations for NP_115879.2

    Status: VALIDATED

    Source sequence(s)
    AL110118, BC021733
    Consensus CDS
    CCDS41981.1
    UniProtKB/Swiss-Prot
    Q9BXV9
    Related
    ENSP00000306320.4, ENST00000306954.5
    Conserved Domains (1) summary
    pfam15387
    Location:398
    DUF4611; Domain of unknown function (DUF4611)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p13 Primary Assembly

    Range
    93202894..93207065 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p13 ALT_REF_LOCI_1

Genomic

  1. NT_187601.1 Reference GRCh38.p13 ALT_REF_LOCI_1

    Range
    317456..321627 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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