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APT2 adenine phosphoribosyl transferase 2 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 844345, updated on 11-Apr-2024

Summary

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Gene symbol
APT2
Gene description
adenine phosphoribosyl transferase 2
Primary source
Araport:AT1G80050
Locus tag
AT1G80050
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
adenine phosphoribosyl transferase 2; ATAPT2; F18B13.14; F18B13_14; PHT1.1
Summary
Encodes an adenosine phosphoribosyl transferase(E.C:2.4.2.7), a constitutively expressed enzyme involved in the one-step salvage of adenine to AMP. This isozyme has high affinity for cytokinins and is likely to be localized to the cytosol.
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Genomic context

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Location:
chromosome: 1
Exon count:
6
Sequence:
Chromosome: 1; NC_003070.9 (30111497..30114010, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene Molecular chaperone Hsp40/DnaJ family protein Neighboring gene ubiquitin system component Cue Neighboring gene Ubiquitin-like superfamily protein Neighboring gene Pre-mRNA-processing-splicing factor

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The cloning of two Arabidopsis genes belonging to a phosphate transporter family. Smith FW, et al. Plant J, 1997 Jan. PMID 9025304
  2. A second form of adenine phosphoribosyltransferase in Arabidopsis thaliana with relative specificity towards cytokinins. Schnorr KM, et al. Plant J, 1996 Jun. PMID 8696367
  3. Adenine phosphoribosyltransferase isoforms of Arabidopsis and their potential contributions to adenine and cytokinin metabolism. Allen M, et al. Physiol Plant, 2002 May. PMID 12010467
  4. Identification of new intrinsic proteins in Arabidopsis plasma membrane proteome. Marmagne A, et al. Mol Cell Proteomics, 2004 Jul. PMID 15060130
  5. Isolation and proteomic characterization of the Arabidopsis Golgi defines functional and novel components involved in plant cell wall biosynthesis. Parsons HT, et al. Plant Physiol, 2012 May. PMID 22430844, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_001334951.1
NM_106654.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables adenine phosphoribosyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables adenine phosphoribosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables adenine phosphoribosyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables phosphate transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in AMP salvage IEA
Inferred from Electronic Annotation
more info
  
involved_in adenine salvage IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within adenine salvage TAS
Traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within phosphate ion transmembrane transport ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus HDA PubMed 
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
located_in cytosol ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
located_in plasma membrane HDA PubMed 

General protein information

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Preferred Names
adenine phosphoribosyl transferase 2
NP_178122.1
  • adenine phosphoribosyl transferase 2 (APT2); FUNCTIONS IN: phosphate transmembrane transporter activity, adenine phosphoribosyltransferase activity; INVOLVED IN: adenine salvage; LOCATED IN: cytosol, plasma membrane; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Adenine phosphoribosyl transferase (InterPro:IPR005764), Phosphoribosyltransferase (InterPro:IPR000836); BEST Arabidopsis thaliana protein match is: adenine phosphoribosyltransferase 5 (TAIR:AT5G11160.1); Has 8411 Blast hits to 8411 proteins in 2474 species: Archae - 199; Bacteria - 5670; Metazoa - 171; Fungi - 181; Plants - 165; Viruses - 0; Other Eukaryotes - 2025 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    30111497..30114010 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_106654.3 → NP_178122.1  adenine phosphoribosyl transferase 2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_178122.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q39004, Q42563
    UniProtKB/TrEMBL
    A0A178W1K2, A0A5S9WVX8
    Conserved Domains (1) summary
    PLN02293
    Location:1 → 187
    PLN02293; adenine phosphoribosyltransferase

  2. NM_001334951.1 → NP_001320554.1  adenine phosphoribosyl transferase 2 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8AN73, A0A5S9WVX8
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q42563.1

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