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CYSTM1 cysteine rich transmembrane module containing 1 [ Homo sapiens (human) ]

Gene ID: 84418, updated on 12-Oct-2019

Summary

Official Symbol
CYSTM1provided by HGNC
Official Full Name
cysteine rich transmembrane module containing 1provided by HGNC
Primary source
HGNC:HGNC:30239
See related
Ensembl:ENSG00000120306
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C5orf32; ORF1-FL49
Expression
Biased expression in stomach (RPKM 391.9), duodenum (RPKM 108.1) and 13 other tissues See more
Orthologs

Genomic context

See CYSTM1 in Genome Data Viewer
Location:
5q31.3
Exon count:
3
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 5 NC_000005.10 (140175188..140243789)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (139554653..139623374)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene IgA inducing protein Neighboring gene uncharacterized LOC101929719 Neighboring gene prefoldin subunit 1 Neighboring gene heparin binding EGF like growth factor

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Pathways from BioSystems

  • Immune System, organism-specific biosystem (from REACTOME)
    Immune System, organism-specific biosystemHumans are exposed to millions of potential pathogens daily, through contact, ingestion, and inhalation. Our ability to avoid infection depends on the adaptive immune system and during the first crit...
  • Innate Immune System, organism-specific biosystem (from REACTOME)
    Innate Immune System, organism-specific biosystemInnate immunity encompases the nonspecific part of immunity tha are part of an individual's natural biologic makeup
  • Neutrophil degranulation, organism-specific biosystem (from REACTOME)
    Neutrophil degranulation, organism-specific biosystemNeutrophils are the most abundant leukocytes (white blood cells), indispensable in defending the body against invading microorganisms. In response to infection, neutrophils leave the circulation and ...

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
biological_process ND
No biological Data available
more info
 
neutrophil degranulation TAS
Traceable Author Statement
more info
 
Component Evidence Code Pubs
extracellular exosome HDA PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane TAS
Traceable Author Statement
more info
 
tertiary granule membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
cysteine-rich and transmembrane domain-containing protein 1
Names
UPF0467 protein C5orf32
putative nuclear protein ORF1-FL49

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_032412.4NP_115788.1  cysteine-rich and transmembrane domain-containing protein 1

    See identical proteins and their annotated locations for NP_115788.1

    Status: VALIDATED

    Source sequence(s)
    BC013643, CA310907
    Consensus CDS
    CCDS4221.1
    UniProtKB/Swiss-Prot
    Q9H1C7
    Related
    ENSP00000261811.4, ENST00000261811.6

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20190905

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p13 Primary Assembly

    Range
    140175188..140243789
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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