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CYSTM1 cysteine rich transmembrane module containing 1 [ Homo sapiens (human) ]

Gene ID: 84418, updated on 10-Oct-2023

Summary

Official Symbol
CYSTM1provided by HGNC
Official Full Name
cysteine rich transmembrane module containing 1provided by HGNC
Primary source
HGNC:HGNC:30239
See related
Ensembl:ENSG00000120306 AllianceGenome:HGNC:30239
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C5orf32; ORF1-FL49
Summary
Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in stomach (RPKM 391.9), duodenum (RPKM 108.1) and 13 other tissues See more
Orthologs
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Genomic context

See CYSTM1 in Genome Data Viewer
Location:
5q31.3
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (140175188..140243789)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (140700285..140769231)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (139554773..139623374)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:139525474-139526020 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:139526021-139526567 Neighboring gene IgA inducing protein Neighboring gene uncharacterized LOC124901086 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:139533596-139534255 Neighboring gene uncharacterized LOC101929719 Neighboring gene ReSE screen-validated silencer GRCh37_chr5:139549390-139549585 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23262 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16446 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23263 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23264 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:139618811-139619649 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:139620488-139621326 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:139621327-139622163 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr5:139638840-139640039 Neighboring gene prefoldin subunit 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:139654428-139654928 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:139654929-139655429 Neighboring gene H3K27ac hESC enhancer GRCh37_chr5:139678515-139679031 Neighboring gene ReSE screen-validated silencer GRCh37_chr5:139682591-139682795 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23266 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23267 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr5:139702306-139703505 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16447 Neighboring gene heparin binding EGF like growth factor

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
located_in extracellular exosome HDA PubMed 
located_in plasma membrane TAS
Traceable Author Statement
more info
 
located_in tertiary granule membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
cysteine-rich and transmembrane domain-containing protein 1
Names
UPF0467 protein C5orf32
putative nuclear protein ORF1-FL49

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_032412.4NP_115788.1  cysteine-rich and transmembrane domain-containing protein 1

    See identical proteins and their annotated locations for NP_115788.1

    Status: VALIDATED

    Source sequence(s)
    BC013643, CA310907
    Consensus CDS
    CCDS4221.1
    UniProtKB/Swiss-Prot
    Q8TBA5, Q9H1C7
    Related
    ENSP00000261811.4, ENST00000261811.6

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

    Range
    140175188..140243789
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060929.1 Alternate T2T-CHM13v2.0

    Range
    140700285..140769231
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)