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CYSTM1 cysteine rich transmembrane module containing 1 [ Homo sapiens (human) ]

Gene ID: 84418, updated on 12-Oct-2019


Official Symbol
CYSTM1provided by HGNC
Official Full Name
cysteine rich transmembrane module containing 1provided by HGNC
Primary source
See related
Gene type
protein coding
RefSeq status
Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C5orf32; ORF1-FL49
Biased expression in stomach (RPKM 391.9), duodenum (RPKM 108.1) and 13 other tissues See more

Genomic context

See CYSTM1 in Genome Data Viewer
Exon count:
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 5 NC_000005.10 (140175188..140243789)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (139554653..139623374)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene IgA inducing protein Neighboring gene uncharacterized LOC101929719 Neighboring gene prefoldin subunit 1 Neighboring gene heparin binding EGF like growth factor

Genomic regions, transcripts, and products


  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Pathways from BioSystems

  • Immune System, organism-specific biosystem (from REACTOME)
    Immune System, organism-specific biosystemHumans are exposed to millions of potential pathogens daily, through contact, ingestion, and inhalation. Our ability to avoid infection depends on the adaptive immune system and during the first crit...
  • Innate Immune System, organism-specific biosystem (from REACTOME)
    Innate Immune System, organism-specific biosystemInnate immunity encompases the nonspecific part of immunity tha are part of an individual's natural biologic makeup
  • Neutrophil degranulation, organism-specific biosystem (from REACTOME)
    Neutrophil degranulation, organism-specific biosystemNeutrophils are the most abundant leukocytes (white blood cells), indispensable in defending the body against invading microorganisms. In response to infection, neutrophils leave the circulation and ...


Products Interactant Other Gene Complex Source Pubs Description

General gene information



Gene Ontology Provided by GOA

Function Evidence Code Pubs
molecular_function ND
No biological Data available
more info
Process Evidence Code Pubs
biological_process ND
No biological Data available
more info
neutrophil degranulation TAS
Traceable Author Statement
more info
Component Evidence Code Pubs
extracellular exosome HDA PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
plasma membrane TAS
Traceable Author Statement
more info
tertiary granule membrane TAS
Traceable Author Statement
more info

General protein information

Preferred Names
cysteine-rich and transmembrane domain-containing protein 1
UPF0467 protein C5orf32
putative nuclear protein ORF1-FL49

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_032412.4NP_115788.1  cysteine-rich and transmembrane domain-containing protein 1

    See identical proteins and their annotated locations for NP_115788.1

    Status: VALIDATED

    Source sequence(s)
    BC013643, CA310907
    Consensus CDS
    ENSP00000261811.4, ENST00000261811.6

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20190905

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly


  1. NC_000005.10 Reference GRCh38.p13 Primary Assembly

    GenBank, FASTA, Sequence Viewer (Graphics)
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