U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Robo2 roundabout guidance receptor 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 84409, updated on 22-May-2022

Summary

Official Symbol
Robo2provided by RGD
Official Full Name
roundabout guidance receptor 2provided by RGD
Primary source
RGD:620167
See related
Ensembl:ENSRNOG00000029598 AllianceGenome:RGD:620167
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Enables axon guidance receptor activity. Involved in axon guidance; brain development; and spinal cord development. Predicted to be located in axolemma and cell surface. Human ortholog(s) of this gene implicated in vesicoureteral reflux. Orthologous to human ROBO2 (roundabout guidance receptor 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Brain (RPKM 136.1), Lung (RPKM 47.8) and 8 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Robo2 in Genome Data Viewer
Location:
11p11
Exon count:
34
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (12528949..14096726, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (11062866..12618793, complement)

Chromosome 11 - NC_051346.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA48 Neighboring gene U1 spliceosomal RNA Neighboring gene uncharacterized LOC120095537 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene transfer RNA alanine (anticodon AGC) Neighboring gene terminal nucleotidyltransferase 5B, pseudogene 1 Neighboring gene U6 spliceosomal RNA Neighboring gene RNA binding motif protein 11 Neighboring gene lipase I

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables axon guidance receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in Roundabout signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in aorta development ISO
Inferred from Sequence Orthology
more info
 
involved_in aortic valve morphogenesis ISO
Inferred from Sequence Orthology
more info
 
involved_in apoptotic process involved in luteolysis ISO
Inferred from Sequence Orthology
more info
 
involved_in axon guidance IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within axon guidance ISO
Inferred from Sequence Orthology
more info
 
involved_in axon midline choice point recognition ISO
Inferred from Sequence Orthology
more info
 
involved_in brain development IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in brain development ISO
Inferred from Sequence Orthology
more info
 
involved_in cellular response to hormone stimulus ISO
Inferred from Sequence Orthology
more info
 
involved_in endocardial cushion formation ISO
Inferred from Sequence Orthology
more info
 
involved_in homophilic cell adhesion via plasma membrane adhesion molecules ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within metanephros development ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of negative chemotaxis ISO
Inferred from Sequence Orthology
more info
 
involved_in olfactory bulb interneuron development ISO
Inferred from Sequence Orthology
more info
 
involved_in outflow tract septum morphogenesis ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of Notch signaling pathway involved in heart induction ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of axonogenesis ISO
Inferred from Sequence Orthology
more info
 
involved_in pulmonary valve morphogenesis ISO
Inferred from Sequence Orthology
more info
 
involved_in retinal ganglion cell axon guidance ISO
Inferred from Sequence Orthology
more info
 
involved_in spinal cord development IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in ureteric bud development ISO
Inferred from Sequence Orthology
more info
 
involved_in ventricular septum morphogenesis ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in axolemma ISO
Inferred from Sequence Orthology
more info
 
located_in cell surface ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
roundabout homolog 2
Names
roundabout 2

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_032106.3NP_115289.2  roundabout homolog 2 precursor

    Status: VALIDATED

    Source sequence(s)
    JACYVU010000221
    Related
    ENSRNOP00000070966.2, ENSRNOT00000088878.2
    Conserved Domains (6) summary
    cd00063
    Location:522615
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00096
    Location:136139
    Ig; Ig strand A [structural motif]
    cd05726
    Location:315412
    IgI_4_Robo; Fourth immunoglobulin (Ig)-like domain in Robo (roundabout) receptors; member of the I-set of Ig superfamily (IgSF) domains
    cd07693
    Location:31129
    IgC_1_Robo; First immunoglobulin (Ig)-like constant domain in Robo (roundabout) receptors, and similar domains
    cd20952
    Location:419505
    IgI_5_Robo; Fifth Ig-like domain of Roundabout (Robo) homolog 1/2, and similar domains; a member of the I-set of IgSF domains
    cl11960
    Location:136221
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051346.1 Reference mRatBN7.2 Primary Assembly

    Range
    12528949..14096726 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039088674.1XP_038944602.1  roundabout homolog 2 isoform X4

    Conserved Domains (6) summary
    cd00063
    Location:541634
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00096
    Location:151154
    Ig; Ig strand A [structural motif]
    cd05726
    Location:334431
    IgI_4_Robo; Fourth immunoglobulin (Ig)-like domain in Robo (roundabout) receptors; member of the I-set of Ig superfamily (IgSF) domains
    cd07693
    Location:46144
    IgC_1_Robo; First immunoglobulin (Ig)-like constant domain in Robo (roundabout) receptors, and similar domains
    cd20952
    Location:438524
    IgI_5_Robo; Fifth Ig-like domain of Roundabout (Robo) homolog 1/2, and similar domains; a member of the I-set of IgSF domains
    cl11960
    Location:151236
    Ig; Immunoglobulin domain
  2. XM_039088673.1XP_038944601.1  roundabout homolog 2 isoform X3

    Conserved Domains (6) summary
    cd00063
    Location:545638
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00096
    Location:159162
    Ig; Ig strand A [structural motif]
    cd05726
    Location:338435
    IgI_4_Robo; Fourth immunoglobulin (Ig)-like domain in Robo (roundabout) receptors; member of the I-set of Ig superfamily (IgSF) domains
    cd07693
    Location:54152
    IgC_1_Robo; First immunoglobulin (Ig)-like constant domain in Robo (roundabout) receptors, and similar domains
    cd20952
    Location:442528
    IgI_5_Robo; Fifth Ig-like domain of Roundabout (Robo) homolog 1/2, and similar domains; a member of the I-set of IgSF domains
    cl11960
    Location:159244
    Ig; Immunoglobulin domain
  3. XM_039088672.1XP_038944600.1  roundabout homolog 2 isoform X2

    Conserved Domains (6) summary
    cd00063
    Location:549642
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00096
    Location:159162
    Ig; Ig strand A [structural motif]
    cd05726
    Location:342439
    IgI_4_Robo; Fourth immunoglobulin (Ig)-like domain in Robo (roundabout) receptors; member of the I-set of Ig superfamily (IgSF) domains
    cd07693
    Location:54152
    IgC_1_Robo; First immunoglobulin (Ig)-like constant domain in Robo (roundabout) receptors, and similar domains
    cd20952
    Location:446532
    IgI_5_Robo; Fifth Ig-like domain of Roundabout (Robo) homolog 1/2, and similar domains; a member of the I-set of IgSF domains
    cl11960
    Location:159244
    Ig; Immunoglobulin domain
  4. XM_039088671.1XP_038944599.1  roundabout homolog 2 isoform X1

    Conserved Domains (6) summary
    cd00063
    Location:549642
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00096
    Location:159162
    Ig; Ig strand A [structural motif]
    cd05726
    Location:342439
    IgI_4_Robo; Fourth immunoglobulin (Ig)-like domain in Robo (roundabout) receptors; member of the I-set of Ig superfamily (IgSF) domains
    cd07693
    Location:54152
    IgC_1_Robo; First immunoglobulin (Ig)-like constant domain in Robo (roundabout) receptors, and similar domains
    cd20952
    Location:446532
    IgI_5_Robo; Fifth Ig-like domain of Roundabout (Robo) homolog 1/2, and similar domains; a member of the I-set of IgSF domains
    cl11960
    Location:159244
    Ig; Immunoglobulin domain
  5. XM_039088680.1XP_038944608.1  roundabout homolog 2 isoform X13

    Conserved Domains (6) summary
    cd00063
    Location:549642
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00096
    Location:159162
    Ig; Ig strand A [structural motif]
    cd05726
    Location:342439
    IgI_4_Robo; Fourth immunoglobulin (Ig)-like domain in Robo (roundabout) receptors; member of the I-set of Ig superfamily (IgSF) domains
    cd07693
    Location:54152
    IgC_1_Robo; First immunoglobulin (Ig)-like constant domain in Robo (roundabout) receptors, and similar domains
    cd20952
    Location:446532
    IgI_5_Robo; Fifth Ig-like domain of Roundabout (Robo) homolog 1/2, and similar domains; a member of the I-set of IgSF domains
    cl11960
    Location:159244
    Ig; Immunoglobulin domain
  6. XM_039088676.1XP_038944604.1  roundabout homolog 2 isoform X7

    Conserved Domains (6) summary
    cd00063
    Location:545638
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00096
    Location:159162
    Ig; Ig strand A [structural motif]
    cd05726
    Location:338435
    IgI_4_Robo; Fourth immunoglobulin (Ig)-like domain in Robo (roundabout) receptors; member of the I-set of Ig superfamily (IgSF) domains
    cd07693
    Location:54152
    IgC_1_Robo; First immunoglobulin (Ig)-like constant domain in Robo (roundabout) receptors, and similar domains
    cd20952
    Location:442528
    IgI_5_Robo; Fifth Ig-like domain of Roundabout (Robo) homolog 1/2, and similar domains; a member of the I-set of IgSF domains
    cl11960
    Location:159244
    Ig; Immunoglobulin domain
  7. XM_039088677.1XP_038944605.1  roundabout homolog 2 isoform X8

    Conserved Domains (6) summary
    cd00063
    Location:549642
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00096
    Location:159162
    Ig; Ig strand A [structural motif]
    cd05726
    Location:342439
    IgI_4_Robo; Fourth immunoglobulin (Ig)-like domain in Robo (roundabout) receptors; member of the I-set of Ig superfamily (IgSF) domains
    cd07693
    Location:54152
    IgC_1_Robo; First immunoglobulin (Ig)-like constant domain in Robo (roundabout) receptors, and similar domains
    cd20952
    Location:446532
    IgI_5_Robo; Fifth Ig-like domain of Roundabout (Robo) homolog 1/2, and similar domains; a member of the I-set of IgSF domains
    cl11960
    Location:159244
    Ig; Immunoglobulin domain
  8. XM_039088687.1XP_038944615.1  roundabout homolog 2 isoform X21

    Conserved Domains (6) summary
    cd00063
    Location:549642
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00096
    Location:159162
    Ig; Ig strand A [structural motif]
    cd05726
    Location:342439
    IgI_4_Robo; Fourth immunoglobulin (Ig)-like domain in Robo (roundabout) receptors; member of the I-set of Ig superfamily (IgSF) domains
    cd07693
    Location:54152
    IgC_1_Robo; First immunoglobulin (Ig)-like constant domain in Robo (roundabout) receptors, and similar domains
    cd20952
    Location:446532
    IgI_5_Robo; Fifth Ig-like domain of Roundabout (Robo) homolog 1/2, and similar domains; a member of the I-set of IgSF domains
    cl11960
    Location:159244
    Ig; Immunoglobulin domain
  9. XM_017598079.2XP_017453568.1  roundabout homolog 2 isoform X6

  10. XM_039088679.1XP_038944607.1  roundabout homolog 2 isoform X10

    Conserved Domains (6) summary
    cd00063
    Location:549642
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00096
    Location:159162
    Ig; Ig strand A [structural motif]
    cd05726
    Location:342439
    IgI_4_Robo; Fourth immunoglobulin (Ig)-like domain in Robo (roundabout) receptors; member of the I-set of Ig superfamily (IgSF) domains
    cd07693
    Location:54152
    IgC_1_Robo; First immunoglobulin (Ig)-like constant domain in Robo (roundabout) receptors, and similar domains
    cd20952
    Location:446532
    IgI_5_Robo; Fifth Ig-like domain of Roundabout (Robo) homolog 1/2, and similar domains; a member of the I-set of IgSF domains
    cl11960
    Location:159244
    Ig; Immunoglobulin domain
  11. XM_039088684.1XP_038944612.1  roundabout homolog 2 isoform X17

    Conserved Domains (6) summary
    cd00063
    Location:549642
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00096
    Location:159162
    Ig; Ig strand A [structural motif]
    cd05726
    Location:342439
    IgI_4_Robo; Fourth immunoglobulin (Ig)-like domain in Robo (roundabout) receptors; member of the I-set of Ig superfamily (IgSF) domains
    cd07693
    Location:54152
    IgC_1_Robo; First immunoglobulin (Ig)-like constant domain in Robo (roundabout) receptors, and similar domains
    cd20952
    Location:446532
    IgI_5_Robo; Fifth Ig-like domain of Roundabout (Robo) homolog 1/2, and similar domains; a member of the I-set of IgSF domains
    cl11960
    Location:159244
    Ig; Immunoglobulin domain
  12. XM_039088681.1XP_038944609.1  roundabout homolog 2 isoform X14

    Conserved Domains (6) summary
    cd00063
    Location:545638
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00096
    Location:159162
    Ig; Ig strand A [structural motif]
    cd05726
    Location:338435
    IgI_4_Robo; Fourth immunoglobulin (Ig)-like domain in Robo (roundabout) receptors; member of the I-set of Ig superfamily (IgSF) domains
    cd07693
    Location:54152
    IgC_1_Robo; First immunoglobulin (Ig)-like constant domain in Robo (roundabout) receptors, and similar domains
    cd20952
    Location:442528
    IgI_5_Robo; Fifth Ig-like domain of Roundabout (Robo) homolog 1/2, and similar domains; a member of the I-set of IgSF domains
    cl11960
    Location:159244
    Ig; Immunoglobulin domain
  13. XM_008768538.3XP_008766760.2  roundabout homolog 2 isoform X11

  14. XM_039088686.1XP_038944614.1  roundabout homolog 2 isoform X20

    Conserved Domains (6) summary
    cd00063
    Location:545638
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00096
    Location:159162
    Ig; Ig strand A [structural motif]
    cd05726
    Location:338435
    IgI_4_Robo; Fourth immunoglobulin (Ig)-like domain in Robo (roundabout) receptors; member of the I-set of Ig superfamily (IgSF) domains
    cd07693
    Location:54152
    IgC_1_Robo; First immunoglobulin (Ig)-like constant domain in Robo (roundabout) receptors, and similar domains
    cd20952
    Location:442528
    IgI_5_Robo; Fifth Ig-like domain of Roundabout (Robo) homolog 1/2, and similar domains; a member of the I-set of IgSF domains
    cl11960
    Location:159244
    Ig; Immunoglobulin domain
  15. XM_017598084.2XP_017453573.1  roundabout homolog 2 isoform X18

  16. XM_017598082.2XP_017453571.1  roundabout homolog 2 isoform X12

  17. XM_039088683.1XP_038944611.1  roundabout homolog 2 isoform X16

    Conserved Domains (6) summary
    cd00063
    Location:545638
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00096
    Location:159162
    Ig; Ig strand A [structural motif]
    cd05726
    Location:338435
    IgI_4_Robo; Fourth immunoglobulin (Ig)-like domain in Robo (roundabout) receptors; member of the I-set of Ig superfamily (IgSF) domains
    cd07693
    Location:54152
    IgC_1_Robo; First immunoglobulin (Ig)-like constant domain in Robo (roundabout) receptors, and similar domains
    cd20952
    Location:442528
    IgI_5_Robo; Fifth Ig-like domain of Roundabout (Robo) homolog 1/2, and similar domains; a member of the I-set of IgSF domains
    cl11960
    Location:159244
    Ig; Immunoglobulin domain
  18. XM_039088685.1XP_038944613.1  roundabout homolog 2 isoform X19

    Conserved Domains (6) summary
    cd00063
    Location:549642
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00096
    Location:159162
    Ig; Ig strand A [structural motif]
    cd05726
    Location:342439
    IgI_4_Robo; Fourth immunoglobulin (Ig)-like domain in Robo (roundabout) receptors; member of the I-set of Ig superfamily (IgSF) domains
    cd07693
    Location:54152
    IgC_1_Robo; First immunoglobulin (Ig)-like constant domain in Robo (roundabout) receptors, and similar domains
    cd20952
    Location:446532
    IgI_5_Robo; Fifth Ig-like domain of Roundabout (Robo) homolog 1/2, and similar domains; a member of the I-set of IgSF domains
    cl11960
    Location:159244
    Ig; Immunoglobulin domain
  19. XM_039088689.1XP_038944617.1  roundabout homolog 2 isoform X24

    Conserved Domains (6) summary
    cd00063
    Location:549642
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00096
    Location:159162
    Ig; Ig strand A [structural motif]
    cd05726
    Location:342439
    IgI_4_Robo; Fourth immunoglobulin (Ig)-like domain in Robo (roundabout) receptors; member of the I-set of Ig superfamily (IgSF) domains
    cd07693
    Location:54152
    IgC_1_Robo; First immunoglobulin (Ig)-like constant domain in Robo (roundabout) receptors, and similar domains
    cd20952
    Location:446532
    IgI_5_Robo; Fifth Ig-like domain of Roundabout (Robo) homolog 1/2, and similar domains; a member of the I-set of IgSF domains
    cl11960
    Location:159244
    Ig; Immunoglobulin domain
  20. XM_039088688.1XP_038944616.1  roundabout homolog 2 isoform X23

    Conserved Domains (6) summary
    cd00063
    Location:545638
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00096
    Location:159162
    Ig; Ig strand A [structural motif]
    cd05726
    Location:338435
    IgI_4_Robo; Fourth immunoglobulin (Ig)-like domain in Robo (roundabout) receptors; member of the I-set of Ig superfamily (IgSF) domains
    cd07693
    Location:54152
    IgC_1_Robo; First immunoglobulin (Ig)-like constant domain in Robo (roundabout) receptors, and similar domains
    cd20952
    Location:442528
    IgI_5_Robo; Fifth Ig-like domain of Roundabout (Robo) homolog 1/2, and similar domains; a member of the I-set of IgSF domains
    cl11960
    Location:159244
    Ig; Immunoglobulin domain
  21. XM_039088682.1XP_038944610.1  roundabout homolog 2 isoform X15

    Conserved Domains (6) summary
    cd00063
    Location:549642
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00096
    Location:159162
    Ig; Ig strand A [structural motif]
    cd05726
    Location:342439
    IgI_4_Robo; Fourth immunoglobulin (Ig)-like domain in Robo (roundabout) receptors; member of the I-set of Ig superfamily (IgSF) domains
    cd07693
    Location:54152
    IgC_1_Robo; First immunoglobulin (Ig)-like constant domain in Robo (roundabout) receptors, and similar domains
    cd20952
    Location:446532
    IgI_5_Robo; Fifth Ig-like domain of Roundabout (Robo) homolog 1/2, and similar domains; a member of the I-set of IgSF domains
    cl11960
    Location:159244
    Ig; Immunoglobulin domain
  22. XM_008768539.3XP_008766761.2  roundabout homolog 2 isoform X22

    Related
    ENSRNOP00000089188.1, ENSRNOT00000099822.1
  23. XM_039088675.1XP_038944603.1  roundabout homolog 2 isoform X5

    Related
    ENSRNOP00000061003.4, ENSRNOT00000065748.4
    Conserved Domains (6) summary
    cd00063
    Location:526619
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00096
    Location:136139
    Ig; Ig strand A [structural motif]
    cd05726
    Location:319416
    IgI_4_Robo; Fourth immunoglobulin (Ig)-like domain in Robo (roundabout) receptors; member of the I-set of Ig superfamily (IgSF) domains
    cd07693
    Location:31129
    IgC_1_Robo; First immunoglobulin (Ig)-like constant domain in Robo (roundabout) receptors, and similar domains
    cd20952
    Location:423509
    IgI_5_Robo; Fifth Ig-like domain of Roundabout (Robo) homolog 1/2, and similar domains; a member of the I-set of IgSF domains
    cl11960
    Location:136221
    Ig; Immunoglobulin domain
  24. XM_039088678.1XP_038944606.1  roundabout homolog 2 isoform X9

    Conserved Domains (6) summary
    cd00063
    Location:522615
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00096
    Location:136139
    Ig; Ig strand A [structural motif]
    cd05726
    Location:315412
    IgI_4_Robo; Fourth immunoglobulin (Ig)-like domain in Robo (roundabout) receptors; member of the I-set of Ig superfamily (IgSF) domains
    cd07693
    Location:31129
    IgC_1_Robo; First immunoglobulin (Ig)-like constant domain in Robo (roundabout) receptors, and similar domains
    cd20952
    Location:419505
    IgI_5_Robo; Fifth Ig-like domain of Roundabout (Robo) homolog 1/2, and similar domains; a member of the I-set of IgSF domains
    cl11960
    Location:136221
    Ig; Immunoglobulin domain