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ABCG25 ATP-binding cassette family G25 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 843527, updated on 19-Feb-2025
Official Symbol
ABCG25
Official Full Name
ATP-binding cassette family G25
Primary source
TAIR:AT1G71960
Locus tag
AT1G71960
See related
Araport:AT1G71960
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ARABIDOPSIS THALIANA ATP-BINDING CASETTE FAMILY G 25; Arabidopsis thaliana ATP-binding cassette G25; ATABCG25; ATP-binding casette family G25; ATP-binding casette G25; F17M19.11; F17M19_11
Summary
Encodes a plasma membrane localized ABC transporter involved in abscisic acid transport and responses.
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See ABCG25 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
4
Sequence:
Chromosome: 1; NC_003070.9 (27082394..27088248, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene SNARE associated Golgi protein family Neighboring gene Proteinase inhibitor, propeptide Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene uncharacterized protein

Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Structural basis for abscisic acid efflux mediated by ABCG25 in Arabidopsis thaliana. Ying W, et al. Nat Plants, 2023 Oct. PMID 37666962, Free PMC Article
  2. Cryo-EM structure and molecular mechanism of abscisic acid transporter ABCG25. Huang X, et al. Nat Plants, 2023 Oct. PMID 37666961
  3. Brachypodium BdABCG25 is a homolog of Arabidopsis AtABCG25 involved in the transport of abscisic acid. Kuromori T, et al. FEBS Lett, 2021 Apr. PMID 32929763
  4. Spatial Regulation of ABCG25, an ABA Exporter, Is an Important Component of the Mechanism Controlling Cellular ABA Levels. Park Y, et al. Plant Cell, 2016 Oct. PMID 27697789, Free PMC Article
  5. Overexpression of AtABCG25 enhances the abscisic acid signal in guard cells and improves plant water use efficiency. Kuromori T, et al. Plant Sci, 2016 Oct. PMID 27593465

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Endomembrane-biased dimerization of ABCG16 and ABCG25 transporters determines their substrate selectivity in ABA-regulated plant growth and stress responses.
    Title: Endomembrane-biased dimerization of ABCG16 and ABCG25 transporters determines their substrate selectivity in ABA-regulated plant growth and stress responses.
  2. Structural basis for abscisic acid efflux mediated by ABCG25 in Arabidopsis thaliana.
    Title: Structural basis for abscisic acid efflux mediated by ABCG25 in Arabidopsis thaliana.
  3. Cryo-EM structure and molecular mechanism of abscisic acid transporter ABCG25.
    Title: Cryo-EM structure and molecular mechanism of abscisic acid transporter ABCG25.
  4. Brachypodium BdABCG25 is a homolog of Arabidopsis AtABCG25 involved in the transport of abscisic acid.
    Title: Brachypodium BdABCG25 is a homolog of Arabidopsis AtABCG25 involved in the transport of abscisic acid.
  5. Data propose that the spatial regulation of ABCG25 is an important component of the mechanism by which plants fine-tune cellular ABA levels according to cellular and environmental conditions
    Title: Spatial Regulation of ABCG25, an ABA Exporter, Is an Important Component of the Mechanism Controlling Cellular ABA Levels.
  6. AtABCG25 overexpression enhances drought tolerance.
    Title: Overexpression of AtABCG25 enhances the abscisic acid signal in guard cells and improves plant water use efficiency.
  7. ABCG25 exports abscisic acid from the endosperm, regulating seed germination.
    Title: Abscisic acid transporters cooperate to control seed germination.
  8. AtABCG25, encodes a protein that is responsible for ABA transport and responses in Arabidopsis. [ABCG25]
    Title: ABC transporter AtABCG25 is involved in abscisic acid transport and responses.
Submit: New GeneRIF Correction
NM_105854.1

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ATPase-coupled transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables ATPase-coupled transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables ATPase-coupled transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables efflux transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables efflux transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within abscisic acid transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in abscisic acid transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in abscisic acid-activated signaling pathway IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in abscisic acid-activated signaling pathway IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in export from cell IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in export from cell IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in intercellular transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in intercellular transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of post-embryonic development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in response to abscisic acid IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within response to abscisic acid IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in response to cold IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in response to heat IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in transmembrane transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in transmembrane transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane ISM
Inferred from Sequence Model
more info
  
Preferred Names
ATP-binding cassette family G25
NP_565030.1
  • ATP-binding casette family G25 (ABCG25); CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), ABC-2 type transporter (InterPro:IPR013525); BEST Arabidopsis thaliana protein match is: ATP-binding cassette 14 (TAIR:AT1G31770.1); Has 400795 Blast hits to 363827 proteins in 4147 species: Archae - 6947; Bacteria - 316897; Metazoa - 8938; Fungi - 6866; Plants - 5594; Viruses - 13; Other Eukaryotes - 55540 (source: NCBI BLink).

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    27082394..27088248 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_105854.1 → NP_565030.1  ATP-binding cassette family G25 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_565030.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    C0Z3C6, Q84TH5, Q949Y4, Q9C8W6
    UniProtKB/TrEMBL
    A0A7G2E583
    Conserved Domains (3) summary
    cd03213
    Location:70 → 290
    ABCG_EPDR; Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily
    PLN03211
    Location:1 → 662
    PLN03211; ABC transporter G-25; Provisional
    pfam01061
    Location:393 → 592
    ABC2_membrane; ABC-2 type transporter
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q84TH5.1

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