RSW10 Ribose 5-phosphate isomerase, type A protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Gene symbol: RSW10
Gene description: Ribose 5-phosphate isomerase, type A protein
Primary source: Araport:AT1G71100
Locus tag: AT1G71100
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: F23N20.9; F23N20_9; RADIAL SWELLING 10; RIBOSE 5-PHOSPHATE ISOMERASE; RPI
Summary: Encodes a ribose 5-phosphate isomerase involved in the formation of uridine used for the synthesis of UDP-sugars. Mutants of this gene are affected in cellulose biosynthesis.
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Genomic context

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Location:: chromosome: 1

Exon count:: 1

Sequence:: Chromosome: 1; NC_003070.9 (26814260..26815922)

Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

A mutation of the ribose-5-phosphate isomerase is characterized and its effects on plant root phenotype is discussed.
Title: A mutation in an Arabidopsis ribose 5-phosphate isomerase reduces cellulose synthesis and is rescued by exogenous uridine.

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Pathways from PubChem

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General gene information

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Markers

At-10C-535 (e-PCR)
- UniSTS:229379

Homology

Orthologs from OrthoDB

NM_105779.4

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables ribose-5-phosphate isomerase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within cellulose biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in pentose-phosphate shunt, non-oxidative branch	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within uridine biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: Ribose 5-phosphate isomerase, type A protein

NP_177266.1

RADIAL SWELLING 10 (RSW10); FUNCTIONS IN: ribose-5-phosphate isomerase activity; INVOLVED IN: uridine biosynthetic process, response to karrikin, cellulose biosynthetic process; LOCATED IN: cytoplasm; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Ribose 5-phosphate isomerase, type A (InterPro:IPR004788); BEST Arabidopsis thaliana protein match is: ribose-5-phosphate isomerase 2 (TAIR:AT2G01290.1); Has 5045 Blast hits to 5045 proteins in 1956 species: Archae - 235; Bacteria - 3584; Metazoa - 111; Fungi - 145; Plants - 141; Viruses - 0; Other Eukaryotes - 829 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003070.9 Reference assembly

Range

26814260..26815922

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_105779.4 → NP_177266.1 Ribose 5-phosphate isomerase, type A protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_177266.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q8LBQ2, Q9C5D1, Q9C998

UniProtKB/TrEMBL

A0A178W9W1, A0A5S9WRI4

Conserved Domains (1) summary

PLN02384
Location:1 → 265

PLN02384; ribose-5-phosphate isomerase