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ELOF1 elongation factor 1 [ Homo sapiens (human) ]

Gene ID: 84337, updated on 6-Sep-2021

Summary

Official Symbol
ELOF1provided by HGNC
Official Full Name
elongation factor 1provided by HGNC
Primary source
HGNC:HGNC:28691
See related
Ensembl:ENSG00000130165
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ELF1
Expression
Broad expression in testis (RPKM 39.1), prostate (RPKM 12.1) and 25 other tissues See more
Orthologs
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Genomic context

See ELOF1 in Genome Data Viewer
Location:
19p13.2
Exon count:
9
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (11553044..11559230, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (11663861..11670045, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene ECSIT signaling integrator Neighboring gene ribosomal protein S12 pseudogene 32 Neighboring gene calponin 1 Neighboring gene zinc finger protein 627 Neighboring gene acid phosphatase 5, tartrate resistant Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene 76

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables RNA polymerase II complex binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in chromatin-mediated maintenance of transcription IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
part_of transcription elongation factor complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
transcription elongation factor 1 homolog
Names
ELF1 homolog, elongation factor 1
elongation factor 1 homolog (ELF1, S. cerevisiae)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001363673.3NP_001350602.2  transcription elongation factor 1 homolog isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC008481
    Consensus CDS
    CCDS86703.1
    Related
    ENSP00000465765.1, ENST00000587806.5
    Conserved Domains (1) summary
    pfam05129
    Location:2080
    Elf1; Transcription elongation factor Elf1 like
  2. NM_001363674.4NP_001350603.2  transcription elongation factor 1 homolog isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC008481, AC009001
    Conserved Domains (1) summary
    pfam05129
    Location:2080
    Elf1; Transcription elongation factor Elf1 like
  3. NM_001363675.4NP_001350604.2  transcription elongation factor 1 homolog isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC008481, AC009001
    Conserved Domains (1) summary
    pfam05129
    Location:2080
    Elf1; Transcription elongation factor Elf1 like
  4. NM_032377.4NP_115753.1  transcription elongation factor 1 homolog isoform 1

    See identical proteins and their annotated locations for NP_115753.1

    Status: VALIDATED

    Source sequence(s)
    AC008481, BG718042
    Consensus CDS
    CCDS12264.1
    UniProtKB/Swiss-Prot
    P60002
    Related
    ENSP00000252445.3, ENST00000252445.7
    Conserved Domains (1) summary
    pfam05129
    Location:2080
    Elf1; Transcription elongation factor Elf1 like

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    11553044..11559230 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017027358.1XP_016882847.1  transcription elongation factor 1 homolog isoform X3

    UniProtKB/Swiss-Prot
    P60002
    Related
    ENSP00000466732.1, ENST00000589171.5
    Conserved Domains (1) summary
    pfam05129
    Location:2080
    Elf1; Transcription elongation factor Elf1 like
  2. XM_017027357.1XP_016882846.1  transcription elongation factor 1 homolog isoform X2

    UniProtKB/TrEMBL
    K7EPC8
    Related
    ENSP00000467330.1, ENST00000591674.5
    Conserved Domains (1) summary
    pfam05129
    Location:2786
    Elf1; Transcription elongation factor Elf1 like
  3. XM_017027359.2XP_016882848.1  transcription elongation factor 1 homolog isoform X3

    UniProtKB/Swiss-Prot
    P60002
    Related
    ENSP00000467914.1, ENST00000586120.5
    Conserved Domains (1) summary
    pfam05129
    Location:2080
    Elf1; Transcription elongation factor Elf1 like
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