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MIEN1 migration and invasion enhancer 1 [ Homo sapiens (human) ]

Gene ID: 84299, updated on 17-Dec-2019

Summary

Official Symbol
MIEN1provided by HGNC
Official Full Name
migration and invasion enhancer 1provided by HGNC
Primary source
HGNC:HGNC:28230
See related
Ensembl:ENSG00000141741 MIM:611802
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C35; ORB3; XTP4; RDX12; C17orf37
Expression
Ubiquitous expression in colon (RPKM 15.4), esophagus (RPKM 14.3) and 25 other tissues See more
Orthologs

Genomic context

See MIEN1 in Genome Data Viewer
Location:
17q12
Exon count:
4
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (39728500..39730563, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (37885409..37886792, complement)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene VISTA enhancer hs1769 Neighboring gene post-GPI attachment to proteins phospholipase 3 Neighboring gene erb-b2 receptor tyrosine kinase 2 Neighboring gene microRNA 4728 Neighboring gene growth factor receptor bound protein 7 Neighboring gene IKAROS family zinc finger 3 Neighboring gene keratin 8 pseudogene 34

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC14832

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
apoptotic process IEA
Inferred from Electronic Annotation
more info
 
negative regulation of apoptotic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of apoptotic process IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of cell migration IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of filopodium assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of filopodium assembly IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
intrinsic component of the cytoplasmic side of the plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
migration and invasion enhancer 1
Names
HBV X-transactivated gene 4 protein
HBV XAg-transactivated protein 4
protein C17orf37

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001330206.1NP_001317135.1  migration and invasion enhancer 1 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC079199, AY508814, BC063395, CR986467
    Consensus CDS
    CCDS82115.1
    UniProtKB/Swiss-Prot
    Q9BRT3
    UniProtKB/TrEMBL
    J3KTI2
    Related
    ENSP00000462998.1, ENST00000577810.1
    Conserved Domains (1) summary
    TIGR02174
    Location:2589
    CXXU_selWTH; selT/selW/selH selenoprotein domain
  2. NM_032339.5NP_115715.3  migration and invasion enhancer 1 isoform 1

    See identical proteins and their annotated locations for NP_115715.3

    Status: VALIDATED

    Source sequence(s)
    AC079199, AY508814, BC006006, BC063395
    Consensus CDS
    CCDS11344.1
    UniProtKB/Swiss-Prot
    Q9BRT3
    Related
    ENSP00000377778.3, ENST00000394231.8
    Conserved Domains (1) summary
    TIGR02174
    Location:2595
    CXXU_selWTH; selT/selW/selH selenoprotein domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

    Range
    39728500..39730563 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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