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UTP23 UTP23 small subunit processome component [ Homo sapiens (human) ]

Gene ID: 84294, updated on 4-Jul-2021

Summary

Official Symbol
UTP23provided by HGNC
Official Full Name
UTP23 small subunit processome componentprovided by HGNC
Primary source
HGNC:HGNC:28224
See related
Ensembl:ENSG00000147679
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C8orf53
Expression
Ubiquitous expression in thyroid (RPKM 6.0), ovary (RPKM 5.7) and 25 other tissues See more
Orthologs
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Genomic context

See UTP23 in Genome Data Viewer
Location:
8q24.11
Exon count:
3
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 8 NC_000008.11 (116766524..116774684)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (117778763..117786923)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 10947 Neighboring gene uncharacterized LOC105375713 Neighboring gene eukaryotic translation initiation factor 3 subunit H Neighboring gene uncharacterized LOC112268030 Neighboring gene RAD21 cohesin complex component Neighboring gene RAD21 antisense RNA 1 Neighboring gene microRNA 3610

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC14595

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables RNA binding HDA PubMed 
enables mRNA 3'-UTR binding IDA
Inferred from Direct Assay
more info
PubMed 
enables mRNA 5'-UTR binding IDA
Inferred from Direct Assay
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables small ribosomal subunit rRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of small-subunit processome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
rRNA-processing protein UTP23 homolog
Names
UTP23, small subunit (SSU) processome component, homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_032334.3NP_115710.2  rRNA-processing protein UTP23 homolog

    See identical proteins and their annotated locations for NP_115710.2

    Status: VALIDATED

    Source sequence(s)
    AC087350, AK315770, AP002905, BP231814
    Consensus CDS
    CCDS6320.1
    UniProtKB/Swiss-Prot
    Q9BRU9
    Related
    ENSP00000308332.2, ENST00000309822.7
    Conserved Domains (1) summary
    cd09866
    Location:2148
    PIN_Fcf1-Utp23-H; PIN domain of rRNA-processing protein Fcf1- and Utp23-like homologs found in eukaryotes except fungi

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p13 Primary Assembly

    Range
    116766524..116774684
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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