Format

Send to:

Choose Destination

ALKBH7 alkB homolog 7 [ Homo sapiens (human) ]

Gene ID: 84266, updated on 7-Jun-2020

Summary

Official Symbol
ALKBH7provided by HGNC
Official Full Name
alkB homolog 7provided by HGNC
Primary source
HGNC:HGNC:21306
See related
Ensembl:ENSG00000125652 MIM:613305
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ABH7; SPATA11; UNQ6002
Expression
Broad expression in testis (RPKM 38.0), kidney (RPKM 14.9) and 24 other tissues See more
Orthologs

Genomic context

See ALKBH7 in Genome Data Viewer
Location:
19p13.3
Exon count:
5
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (6372794..6375250)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (6372444..6375261)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene alkaline ceramidase 1 Neighboring gene caseinolytic mitochondrial matrix peptidase proteolytic subunit Neighboring gene persephin Neighboring gene general transcription factor IIF subunit 1 Neighboring gene microRNA 6885 Neighboring gene microRNA 6790

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC10974

Gene Ontology Provided by GOA

Function Evidence Code Pubs
dioxygenase activity IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
cellular response to DNA damage stimulus IDA
Inferred from Direct Assay
more info
PubMed 
fatty acid metabolic process ISS
Inferred from Sequence or Structural Similarity
more info
 
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 
regulation of lipid storage ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of mitochondrial membrane permeability involved in programmed necrotic cell death IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
mitochondrial matrix IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial
Names
alkB, alkylation repair homolog 7
alkylated DNA repair protein alkB homolog 7
probable alpha-ketoglutarate-dependent dioxygenase ABH7
spermatogenesis associated 11
spermatogenesis cell proliferation related protein
spermatogenesis-associated protein 11

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_032306.4NP_115682.1  alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial precursor

    See identical proteins and their annotated locations for NP_115682.1

    Status: VALIDATED

    Source sequence(s)
    AY358858, BM271861
    Consensus CDS
    CCDS12163.1
    UniProtKB/Swiss-Prot
    Q9BT30
    Related
    ENSP00000245812.2, ENST00000245812.8
    Conserved Domains (1) summary
    cl21496
    Location:28200
    2OG-FeII_Oxy; 2OG-Fe(II) oxygenase superfamily

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    6372794..6375250
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017027355.1XP_016882844.1  alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial isoform X1

  2. XM_005259658.4XP_005259715.1  alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial isoform X2

    See identical proteins and their annotated locations for XP_005259715.1

    Conserved Domains (1) summary
    cl21496
    Location:92174
    2OG-FeII_Oxy; 2OG-Fe(II) oxygenase superfamily
Support Center