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POLR3GL RNA polymerase III subunit G like [ Homo sapiens (human) ]

Gene ID: 84265, updated on 21-Dec-2019

Summary

Official Symbol
POLR3GLprovided by HGNC
Official Full Name
RNA polymerase III subunit G likeprovided by HGNC
Primary source
HGNC:HGNC:28466
See related
Ensembl:ENSG00000121851 MIM:617457
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
RPC32HOM; flj32422
Expression
Ubiquitous expression in fat (RPKM 24.4), spleen (RPKM 14.6) and 25 other tissues See more
Orthologs

Genomic context

See POLR3GL in Genome Data Viewer
Location:
1q21.1
Exon count:
9
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (145959037..145978848)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (145456236..145476081, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene gonadotropin releasing hormone receptor 2 (pseudogene) Neighboring gene RNA binding motif protein 8A Neighboring gene LIX1L antisense RNA 1 Neighboring gene limb and CNS expressed 1 like Neighboring gene conserved acetylation island sequence C12 enhancer Neighboring gene ankyrin repeat domain 34A Neighboring gene POLR3GL-TXNIP intergenic CAGE-defined low expression enhancer Neighboring gene thioredoxin interacting protein

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC3200, FLJ34890

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA-directed 5'-3' RNA polymerase activity IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
positive regulation of type I interferon production TAS
Traceable Author Statement
more info
 
transcription by RNA polymerase III IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
RNA polymerase III complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
RNA polymerase III complex IDA
Inferred from Direct Assay
more info
PubMed 
cytosol TAS
Traceable Author Statement
more info
 
colocalizes_with nuclear chromatin IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
colocalizes_with nuclear chromatin IDA
Inferred from Direct Assay
more info
PubMed 
nucleoplasm TAS
Traceable Author Statement
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
DNA-directed RNA polymerase III subunit RPC7-like
Names
DNA-directed RNA polymerase III subunit G-like
RNA polymerase III 32 kDa beta subunit
RNA polymerase III subunit C7-like
RPC32-beta
RPC32-like protein
alternative RNA polymerase III subunit 32
polymerase (RNA) III (DNA directed) polypeptide G (32kD)-like
polymerase (RNA) III subunit G like

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001330685.1NP_001317614.1  DNA-directed RNA polymerase III subunit RPC7-like isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.
    Source sequence(s)
    BC004355, BI914801, CN261802
    Consensus CDS
    CCDS81367.1
    UniProtKB/Swiss-Prot
    Q9BT43
    UniProtKB/TrEMBL
    A6NGX6
    Related
    ENSP00000358319.3, ENST00000369313.7
    Conserved Domains (1) summary
    pfam11705
    Location:16192
    RNA_pol_3_Rpc31; DNA-directed RNA polymerase III subunit Rpc31
  2. NM_032305.3NP_115681.1  DNA-directed RNA polymerase III subunit RPC7-like isoform 1

    See identical proteins and their annotated locations for NP_115681.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    BC004355, BI914801
    Consensus CDS
    CCDS72875.1
    UniProtKB/Swiss-Prot
    Q9BT43
    Related
    ENSP00000358320.1, ENST00000369314.2
    Conserved Domains (1) summary
    pfam11705
    Location:16204
    RNA_pol_3_Rpc31; DNA-directed RNA polymerase III subunit Rpc31

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    145959037..145978848
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005277431.4XP_005277488.1  DNA-directed RNA polymerase III subunit RPC7-like isoform X1

    See identical proteins and their annotated locations for XP_005277488.1

    UniProtKB/Swiss-Prot
    Q9BT43
    Conserved Domains (1) summary
    pfam11705
    Location:16204
    RNA_pol_3_Rpc31; DNA-directed RNA polymerase III subunit Rpc31
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