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FYTTD1 forty-two-three domain containing 1 [ Homo sapiens (human) ]

Gene ID: 84248, updated on 1-Jun-2020

Summary

Official Symbol
FYTTD1provided by HGNC
Official Full Name
forty-two-three domain containing 1provided by HGNC
Primary source
HGNC:HGNC:25407
See related
Ensembl:ENSG00000122068 MIM:616933
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
UIF
Expression
Ubiquitous expression in testis (RPKM 31.0), esophagus (RPKM 23.1) and 25 other tissues See more
Orthologs

Genomic context

See FYTTD1 in Genome Data Viewer
Location:
3q29
Exon count:
12
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 3 NC_000003.12 (197749553..197787596)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (197476424..197511317)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene rubicon autophagy regulator Neighboring gene Sharpr-MPRA regulatory region 8415 Neighboring gene Sharpr-MPRA regulatory region 6653 Neighboring gene leucine rich repeats and calponin homology domain containing 3 Neighboring gene uncharacterized LOC105374310 Neighboring gene ribosomal protein L17 pseudogene 18 Neighboring gene RNA, U6 small nuclear 858, pseudogene Neighboring gene IQ motif containing G

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • DKFZp761B1514

Gene Ontology Provided by GOA

Function Evidence Code Pubs
RNA binding HDA PubMed 
mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mRNA binding IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
mRNA export from nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mRNA export from nucleus IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
nuclear speck IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nuclear speck IDA
Inferred from Direct Assay
more info
PubMed 
nucleoplasm IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
UAP56-interacting factor
Names
forty-two-three domain-containing protein 1
protein 40-2-3

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001011537.2NP_001011537.2  UAP56-interacting factor isoform 2

    See identical proteins and their annotated locations for NP_001011537.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and 5' coding region, compared to variant 1. The encoded isoform (2) has a distinct N-terminus and is shorter than isoform 1.
    Source sequence(s)
    AJ344094, AK303462, H97483
    Consensus CDS
    CCDS43196.2
    UniProtKB/Swiss-Prot
    Q96QD9
    Related
    ENSP00000393746.2, ENST00000415708.6
    Conserved Domains (1) summary
    pfam07078
    Location:9292
    FYTT; Forty-two-three protein
  2. NM_032288.7NP_115664.2  UAP56-interacting factor isoform 1

    See identical proteins and their annotated locations for NP_115664.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AC055764, AJ344094, BC035006, H97483
    Consensus CDS
    CCDS3329.1
    UniProtKB/Swiss-Prot
    Q96QD9
    UniProtKB/TrEMBL
    A0A024R9K4
    Related
    ENSP00000241502.3, ENST00000241502.9
    Conserved Domains (1) summary
    pfam07078
    Location:13318
    FYTT; Forty-two-three protein

RNA

  1. NR_027840.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) has an alternate 5' exon, compared to variant 1. This variant is represented as non-coding due to the presence of an upstream ORF that is predicted to inhibit the translation of the longest ORF.
    Source sequence(s)
    AC024560, AC055764, AJ344094, AK302546, H97483

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p13 Primary Assembly

    Range
    197749553..197787596
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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