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ATP13A4 ATPase 13A4 [ Homo sapiens (human) ]

Gene ID: 84239, updated on 1-Jun-2020

Summary

Official Symbol
ATP13A4provided by HGNC
Official Full Name
ATPase 13A4provided by HGNC
Primary source
HGNC:HGNC:25422
See related
Ensembl:ENSG00000127249 MIM:609556
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Biased expression in thyroid (RPKM 10.9), lung (RPKM 10.1) and 6 other tissues See more
Orthologs

Genomic context

See ATP13A4 in Genome Data Viewer
Location:
3q29
Exon count:
33
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 3 NC_000003.12 (193398967..193593114, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (193119866..193272810, complement)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene uncharacterized protein MGC2889 Neighboring gene phospholipase A and acyltransferase 1 Neighboring gene ATPase 13A5 Neighboring gene ATP13A5 antisense RNA 1 Neighboring gene ATP13A4 antisense RNA 1 Neighboring gene eukaryotic translation elongation factor 1 alpha 1 pseudogene 23 Neighboring gene OPA1 mitochondrial dynamin like GTPase Neighboring gene OPA1 antisense RNA 1 Neighboring gene uncharacterized LOC102724808

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

General gene information

Homology

Clone Names

  • MGC126545, DKFZp761I1011

Gene Ontology Provided by GOA

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
ATPase activity IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
cation transport IEA
Inferred from Electronic Annotation
more info
 
cellular calcium ion homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ion transmembrane transport TAS
Traceable Author Statement
more info
 
Component Evidence Code Pubs
cell IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
probable cation-transporting ATPase 13A4
Names
ATPase type 13A4
P5-ATPase
cation-transporting P5-ATPase
NP_115655.2
XP_011511534.1
XP_016862807.1
XP_016862808.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_032279.4NP_115655.2  probable cation-transporting ATPase 13A4

    See identical proteins and their annotated locations for NP_115655.2

    Status: VALIDATED

    Source sequence(s)
    AC105057, AK096510, AY358110, AY823162, BC101496, DA117883
    Consensus CDS
    CCDS3304.2
    UniProtKB/Swiss-Prot
    Q4VNC1
    UniProtKB/TrEMBL
    B3KU47
    Related
    ENSP00000339182.4, ENST00000342695.9
    Conserved Domains (6) summary
    COG4087
    Location:820869
    COG4087; Soluble P-type ATPase [General function prediction only]
    TIGR01657
    Location:171114
    P-ATPase-V; P-type ATPase of unknown pump specificity (type V)
    pfam00122
    Location:268471
    E1-E2_ATPase; E1-E2 ATPase
    pfam00690
    Location:157217
    Cation_ATPase_N; Cation transporter/ATPase, N-terminus
    pfam12409
    Location:16136
    P5-ATPase; P5-type ATPase cation transporter
    pfam13246
    Location:595634
    Cation_ATPase; Cation transport ATPase (P-type)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p13 Primary Assembly

    Range
    193398967..193593114 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017007318.1XP_016862807.1  probable cation-transporting ATPase 13A4 isoform X1

    Related
    ENSP00000376238.3, ENST00000392443.7
  2. XM_011513232.2XP_011511534.1  probable cation-transporting ATPase 13A4 isoform X2

    Conserved Domains (5) summary
    COG4087
    Location:820869
    COG4087; Soluble P-type ATPase [General function prediction only]
    pfam00122
    Location:268471
    E1-E2_ATPase; E1-E2 ATPase
    pfam00690
    Location:157217
    Cation_ATPase_N; Cation transporter/ATPase, N-terminus
    pfam12409
    Location:16136
    P5-ATPase; P5-type ATPase cation transporter
    pfam13246
    Location:595634
    Cation_ATPase; Cation transport ATPase (P-type)
  3. XM_017007319.1XP_016862808.1  probable cation-transporting ATPase 13A4 isoform X3

RNA

  1. XR_924191.3 RNA Sequence

  2. XR_001740324.2 RNA Sequence

    Related
    ENST00000450950.6
  3. XR_001740325.1 RNA Sequence

  4. XR_002959602.1 RNA Sequence

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