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CPN60B chaperonin 60 beta [ Arabidopsis thaliana (thale cress) ]

Gene ID: 841996, updated on 11-Oct-2018

Summary

Gene symbol
CPN60B
Gene description
chaperonin 60 beta
Primary source
Araport:AT1G55490
Locus tag
AT1G55490
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
chaperonin 60 beta; chaperonin-60beta1; CPN60BETA; Cpn60beta1; LEN1; LESION INITIATION 1; T5A14.11; T5A14_11
Summary
encodes the beta subunit of the chloroplast chaperonin 60, a homologue of bacterial GroEL. Mutants in this gene develops lesions on its leaves, expresses systemic acquired resistance (SAR) and develops accelerated cell death to heat shock stress. The protein has molecular chaperone activity for suppressing protein aggregation in vitro.

Genomic context

See CPN60B in Genome Data Viewer
Location:
chromosome: 1
Exon count:
15
Sequence:
Chromosome: 1; NC_003070.9 (20715563..20719261, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene protein containing PDZ domain, a K-box domain, and a TPR region Neighboring gene evolutionarily conserved C-terminal region 4 Neighboring gene branched-chain alpha-keto acid decarboxylase E1 beta subunit Neighboring gene TATA binding protein 2

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

  • RNA degradation, organism-specific biosystem (from KEGG)
    RNA degradation, organism-specific biosystemThe correct processing, quality control and turnover of cellular RNA molecules are critical to many aspects in the expression of genetic information. In eukaryotes, two major pathways of mRNA decay e...
  • RNA degradation, conserved biosystem (from KEGG)
    RNA degradation, conserved biosystemThe correct processing, quality control and turnover of cellular RNA molecules are critical to many aspects in the expression of genetic information. In eukaryotes, two major pathways of mRNA decay e...

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

NM_001333710.1
NM_001333711.1
NM_001333712.1
NM_104424.2
NM_179480.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
unfolded protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
'de novo' protein folding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cell death IMP
Inferred from Mutant Phenotype
more info
PubMed 
chaperone cofactor-dependent protein refolding IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein folding TAS
Traceable Author Statement
more info
 
protein refolding IEA
Inferred from Electronic Annotation
more info
 
response to cold IEP
Inferred from Expression Pattern
more info
PubMed 
systemic acquired resistance IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
NOT Golgi apparatus RCA
inferred from Reviewed Computational Analysis
more info
PubMed 
apoplast IDA
Inferred from Direct Assay
more info
PubMed 
chloroplast IDA
Inferred from Direct Assay
more info
PubMed 
chloroplast ISM
Inferred from Sequence Model
more info
 
chloroplast NAS
Non-traceable Author Statement
more info
PubMed 
chloroplast envelope IDA
Inferred from Direct Assay
more info
PubMed 
chloroplast stroma IDA
Inferred from Direct Assay
more info
PubMed 
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
NOT cytosol RCA
inferred from Reviewed Computational Analysis
more info
PubMed 
cytosolic ribosome IDA
Inferred from Direct Assay
more info
PubMed 
membrane IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
stromule IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
chaperonin 60 beta
NP_175945.1
  • chaperonin 60 beta (CPN60B); FUNCTIONS IN: protein binding; INVOLVED IN: protein folding, systemic acquired resistance, cell death, response to cold, chaperone mediated protein folding requiring cofactor; LOCATED IN: in 8 components; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Chaperonin Cpn60/TCP-1 (InterPro:IPR002423), Chaperonin Cpn60, conserved site (InterPro:IPR018370), Chaperonin Cpn60 (InterPro:IPR001844); BEST Arabidopsis thaliana protein match is: TCP-1/cpn60 chaperonin family protein (TAIR:AT3G13470.1); Has 34209 Blast hits to 34175 proteins in 8723 species: Archae - 804; Bacteria - 21846; Metazoa - 1741; Fungi - 1612; Plants - 841; Viruses - 2; Other Eukaryotes - 7363 (source: NCBI BLink).
NP_849811.1
  • chaperonin 60 beta (CPN60B); FUNCTIONS IN: protein binding; INVOLVED IN: protein folding, systemic acquired resistance, cell death, response to cold, chaperone mediated protein folding requiring cofactor; LOCATED IN: in 7 components; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Chaperonin Cpn60/TCP-1 (InterPro:IPR002423), Chaperonin Cpn60, conserved site (InterPro:IPR018370), Chaperonin Cpn60 (InterPro:IPR001844); BEST Arabidopsis thaliana protein match is: TCP-1/cpn60 chaperonin family protein (TAIR:AT3G13470.1); Has 34209 Blast hits to 34175 proteins in 8723 species: Archae - 804; Bacteria - 21846; Metazoa - 1741; Fungi - 1612; Plants - 841; Viruses - 2; Other Eukaryotes - 7363 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    20715563..20719261 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_179480.3NP_849811.1  chaperonin 60 beta [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_849811.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P21240
    UniProtKB/TrEMBL
    A0A178W724
    Conserved Domains (2) summary
    PLN03167
    Location:1600
    PLN03167; Chaperonin-60 beta subunit; Provisional
    PRK12850
    Location:55600
    groEL; chaperonin GroEL; Reviewed
  2. NM_001333712.1NP_001320637.1  chaperonin 60 beta [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P21240
    UniProtKB/TrEMBL
    A0A178W724
  3. NM_001333711.1NP_001320638.1  chaperonin 60 beta [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P21240
    UniProtKB/TrEMBL
    A0A178W724
  4. NM_001333710.1NP_001320639.1  chaperonin 60 beta [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P21240
    UniProtKB/TrEMBL
    A0A178W724
  5. NM_104424.2NP_175945.1  chaperonin 60 beta [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_175945.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P21240
    UniProtKB/TrEMBL
    A0A178W724
    Conserved Domains (2) summary
    PLN03167
    Location:1600
    PLN03167; Chaperonin-60 beta subunit; Provisional
    PRK12850
    Location:55600
    groEL; chaperonin GroEL; Reviewed
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