U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

MYH16 myosin heavy chain 16 pseudogene [ Homo sapiens (human) ]

Gene ID: 84176, updated on 13-May-2022

Summary

Official Symbol
MYH16provided by HGNC
Official Full Name
myosin heavy chain 16 pseudogeneprovided by HGNC
Primary source
HGNC:HGNC:31038
See related
Ensembl:ENSG00000002079 MIM:608580; AllianceGenome:HGNC:31038
Gene type
pseudo
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MYH5; MHC20; MYH16P
Summary
The MYH16 gene, encoding a sarcomeric myosin heavy chain expressed in nonhuman primate masticatory muscles, is inactivated in humans. Stedman et al. (2004) [PubMed 15042088] hypothesized that the decrement in masticatory muscle size caused by the inactivation of MYH16 removed an evolutionary constraint on encephalization in early man.[supplied by OMIM, Mar 2008]
Expression
Low expression observed in reference dataset See more
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See MYH16 in Genome Data Viewer
Location:
7q22.1
Exon count:
41
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (99238829..99311128)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (100477712..100550022)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (98836452..98908751)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene karyopherin subunit alpha 7 Neighboring gene Sharpr-MPRA regulatory region 10979 Neighboring gene Sharpr-MPRA regulatory region 10425 Neighboring gene uncharacterized LOC105375421 Neighboring gene actin related protein 2/3 complex subunit 1A Neighboring gene Sharpr-MPRA regulatory region 4482

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Other Names

  • myosin heavy polypeptide 5
  • myosin, heavy chain 16
  • myosin, heavy polypeptide 16
  • sarcomeric myosin

Clone Names

  • FLJ22037

Gene Ontology Provided by GOA

Component Evidence Code Pubs
is_active_in centriole IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in centrosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of myosin complex IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_002147.3 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC004834, AC005163, AC112711
    Related
    ENST00000439784.7

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

    Range
    99238829..99311128
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060931.1 Alternate T2T-CHM13v2.0

    Range
    100477712..100550022
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)