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QRFPR pyroglutamylated RFamide peptide receptor [ Homo sapiens (human) ]

Gene ID: 84109, updated on 21-Jun-2020

Summary

Official Symbol
QRFPRprovided by HGNC
Official Full Name
pyroglutamylated RFamide peptide receptorprovided by HGNC
Primary source
HGNC:HGNC:15565
See related
Ensembl:ENSG00000186867 MIM:606925
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
AQ27; GPR103; SP9155
Expression
Low expression observed in reference dataset See more
Orthologs

Genomic context

See QRFPR in Genome Data Viewer
Location:
4q27
Exon count:
7
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 4 NC_000004.12 (121328642..121381054, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (122249797..122302181, complement)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105377400 Neighboring gene TNFAIP3 interacting protein 3 Neighboring gene RNA, U6 small nuclear 948, pseudogene Neighboring gene KIAA1191 pseudogene Neighboring gene uncharacterized LOC107986309 Neighboring gene TUBB4B pseudogene 5 Neighboring gene uncharacterized LOC107986310

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC149217

Gene Ontology Provided by GOA

Function Evidence Code Pubs
G protein-coupled receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
G protein-coupled receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
neuropeptide Y receptor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
G protein-coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
G protein-coupled receptor signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
G protein-coupled receptor signaling pathway TAS
Traceable Author Statement
more info
 
neuropeptide signaling pathway IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
integral component of membrane IC
Inferred by Curator
more info
PubMed 
integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
pyroglutamylated RF-amide peptide receptor
Names
G-protein coupled receptor 103
QRFP receptor
orexigenic neuropeptide QRFP receptor
peptide P518 receptor

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_198179.3NP_937822.2  pyroglutamylated RF-amide peptide receptor

    See identical proteins and their annotated locations for NP_937822.2

    Status: VALIDATED

    Source sequence(s)
    AB109629, AC093867, BG169612, DA461055
    Consensus CDS
    CCDS3719.1
    UniProtKB/Swiss-Prot
    Q96P65
    Related
    ENSP00000377948.2, ENST00000394427.3
    Conserved Domains (1) summary
    pfam00001
    Location:62332
    7tm_1; 7 transmembrane receptor (rhodopsin family)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p13 Primary Assembly

    Range
    121328642..121381054 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017008693.2XP_016864182.1  pyroglutamylated RF-amide peptide receptor isoform X1

    UniProtKB/TrEMBL
    F2Z3L3
    Related
    ENSP00000423369.1, ENST00000507331.5
    Conserved Domains (2) summary
    cd14964
    Location:4872
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:46187
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
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