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MYCBPAP MYCBP associated protein [ Homo sapiens (human) ]

Gene ID: 84073, updated on 26-Oct-2022

Summary

Official Symbol
MYCBPAPprovided by HGNC
Official Full Name
MYCBP associated proteinprovided by HGNC
Primary source
HGNC:HGNC:19677
See related
Ensembl:ENSG00000136449 MIM:609835; AllianceGenome:HGNC:19677
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
AMAP1; AMAP-1
Summary
Involved in spermatogenesis. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis (RPKM 33.9) See more
Orthologs
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Genomic context

See MYCBPAP in Genome Data Viewer
Location:
17q21.33
Exon count:
21
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 17 NC_000017.11 (50507778..50531501)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 17 NC_060941.1 (51375537..51398673)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (48585800..48608862)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene acyl-CoA synthetase family member 2 Neighboring gene chondroadherin Neighboring gene Sharpr-MPRA regulatory region 9450 Neighboring gene radical S-adenosyl methionine domain containing 1 Neighboring gene uncharacterized LOC105371824 Neighboring gene epsin 3 Neighboring gene spermatogenesis associated 20

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

EBI GWAS Catalog

Description
Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women.
EBI GWAS Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • DKFZp434N1415

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 
involved_in chemical synaptic transmission ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in spermatogenesis IEP
Inferred from Expression Pattern
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in synapse IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
MYCBP-associated protein
Names
AMAM-1
AMY-1-binding protein 1
AMY1-associating protein 1
testis secretory sperm-binding protein Li 214e

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001366294.2NP_001353223.1  MYCBP-associated protein isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC021491
    Conserved Domains (1) summary
    pfam14646
    Location:208626
    MYCBPAP; MYCBP-associated protein family
  2. NM_032133.6NP_115509.5  MYCBP-associated protein isoform 1

    Status: VALIDATED

    Source sequence(s)
    AB083068, AK303041
    Consensus CDS
    CCDS32680.3
    Related
    ENSP00000323184.6, ENST00000323776.11
    Conserved Domains (1) summary
    pfam14646
    Location:193611
    MYCBPAP; MYCBP-associated protein family

RNA

  1. NR_158785.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC021491

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p14 Primary Assembly

    Range
    50507778..50531501
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047436908.1XP_047292864.1  MYCBP-associated protein isoform X6

  2. XM_005257726.3XP_005257783.1  MYCBP-associated protein isoform X3

    Conserved Domains (1) summary
    pfam14646
    Location:251669
    MYCBPAP; MYCBP-associated protein family
  3. XM_017025205.2XP_016880694.1  MYCBP-associated protein isoform X1

  4. XM_047436905.1XP_047292861.1  MYCBP-associated protein isoform X2

  5. XM_047436906.1XP_047292862.1  MYCBP-associated protein isoform X4

  6. XM_047436907.1XP_047292863.1  MYCBP-associated protein isoform X5

  7. XM_011525342.2XP_011523644.1  MYCBP-associated protein isoform X7

    Conserved Domains (1) summary
    pfam14646
    Location:251669
    MYCBPAP; MYCBP-associated protein family
  8. XM_011525343.2XP_011523645.1  MYCBP-associated protein isoform X8

    Conserved Domains (1) summary
    pfam14646
    Location:251478
    MYCBPAP; MYCBP-associated protein family

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060941.1 Alternate T2T-CHM13v2.0

    Range
    51375537..51398673
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)