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IFI27L2 interferon alpha inducible protein 27 like 2 [ Homo sapiens (human) ]

Gene ID: 83982, updated on 1-Jun-2020

Summary

Official Symbol
IFI27L2provided by HGNC
Official Full Name
interferon alpha inducible protein 27 like 2provided by HGNC
Primary source
HGNC:HGNC:19753
See related
Ensembl:ENSG00000119632 MIM:611319
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TLH29; FAM14A; ISG12B
Expression
Ubiquitous expression in adrenal (RPKM 32.8), brain (RPKM 28.7) and 25 other tissues See more
Orthologs

Genomic context

See IFI27L2 in Genome Data Viewer
Location:
14q32.12
Exon count:
4
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 14 NC_000014.9 (94127781..94129604, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (94594118..94595957, complement)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene interferon alpha inducible protein 27 like 1 Neighboring gene interferon alpha inducible protein 27 Neighboring gene uncharacterized LOC105370634 Neighboring gene protein phosphatase 4 regulatory subunit 4

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Homology

Clone Names

  • MGC44913

Gene Ontology Provided by GOA

Process Evidence Code Pubs
apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
apoptotic signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
mitochondrial membrane IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
interferon alpha-inducible protein 27-like protein 2
Names
ISG12(b) protein
family with sequence similarity 14, member A
interferon-stimulated gene 12b protein
pIFI27-like protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_032036.3NP_114425.1  interferon alpha-inducible protein 27-like protein 2

    See identical proteins and their annotated locations for NP_114425.1

    Status: VALIDATED

    Source sequence(s)
    BC032626, BE737110
    Consensus CDS
    CCDS9920.1
    UniProtKB/Swiss-Prot
    Q9H2X8
    Related
    ENSP00000238609.3, ENST00000238609.4
    Conserved Domains (1) summary
    pfam06140
    Location:2088
    Ifi-6-16; Interferon-induced 6-16 family

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p13 Primary Assembly

    Range
    94127781..94129604 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p13 ALT_REF_LOCI_1

Genomic

  1. NT_187601.1 Reference GRCh38.p13 ALT_REF_LOCI_1

    Range
    1242343..1244166 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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