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TSSK1B testis specific serine kinase 1B [ Homo sapiens (human) ]

Gene ID: 83942, updated on 17-Jun-2019

Summary

Official Symbol
TSSK1Bprovided by HGNC
Official Full Name
testis specific serine kinase 1Bprovided by HGNC
Primary source
HGNC:HGNC:14968
See related
Ensembl:ENSG00000212122 MIM:610709
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TSK1; TSSK1; FKSG81; SPOGA4; STK22D
Summary
TSSK1 belongs to a family of serine/threonine kinases highly expressed in testis (Hao et al., 2004 [PubMed 15044604]).[supplied by OMIM, Mar 2008]
Orthologs

Genomic context

See TSSK1B in Genome Data Viewer
Location:
5q22.2
Exon count:
1
Annotation release Status Assembly Chr Location
109.20190607 current GRCh38.p13 (GCF_000001405.39) 5 NC_000005.10 (113432553..113434989, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (112768251..112770728, complement)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105379126 Neighboring gene decapping mRNA 2 Neighboring gene MCC regulator of WNT signaling pathway Neighboring gene uncharacterized LOC107986366 Neighboring gene RNA, U4atac small nuclear 13, pseudogene Neighboring gene YTH domain containing 2

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
ATP binding IDA
Inferred from Direct Assay
more info
PubMed 
magnesium ion binding IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein serine/threonine kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
protein-containing complex binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
intracellular signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
peptidyl-serine phosphorylation IEA
Inferred from Electronic Annotation
more info
 
protein phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein phosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
spermatid development ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
acrosomal vesicle IEA
Inferred from Electronic Annotation
more info
 
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
motile cilium ISS
Inferred from Sequence or Structural Similarity
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
testis-specific serine/threonine-protein kinase 1
Names
TSK-1
TSSK-1
serine/threonine kinase 22D (spermiogenesis associated)
serine/threonine kinase FKSG81
serine/threonine-protein kinase 22A
spermiogenesis associated 4
testis tissue sperm-binding protein Li 55e
testis-specific kinase 1
testis-specific serine kinase 1
NP_114417.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_032028.4NP_114417.1  testis-specific serine/threonine-protein kinase 1

    See identical proteins and their annotated locations for NP_114417.1

    Status: VALIDATED

    Source sequence(s)
    AC010431, AK122904, BC022515, DB025324, DB527624
    Consensus CDS
    CCDS4112.1
    UniProtKB/Swiss-Prot
    Q9BXA7
    UniProtKB/TrEMBL
    A0ZT98
    Related
    ENSP00000375081.3, ENST00000390666.3
    Conserved Domains (1) summary
    cd14165
    Location:10272
    STKc_TSSK1_2-like; Catalytic domain of testis-specific serine/threonine kinase 1, TSSK2, and similar proteins

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p13 Primary Assembly

    Range
    113432553..113434989 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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