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WDR87 WD repeat domain 87 [ Homo sapiens (human) ]

Gene ID: 83889, updated on 23-Nov-2021

Summary

Official Symbol
WDR87provided by HGNC
Official Full Name
WD repeat domain 87provided by HGNC
Primary source
HGNC:HGNC:29934
See related
Ensembl:ENSG00000171804
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
NYD-SP11
Expression
Restricted expression toward testis (RPKM 11.3) See more
Orthologs
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Genomic context

See WDR87 in Genome Data Viewer
Location:
19q13.13
Exon count:
6
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (37884577..37906617, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (38375463..38397234, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC644554 Neighboring gene WD repeat domain 87 pseudogene Neighboring gene WD repeat domain 87B, pseudogene Neighboring gene uncharacterized LOC105372395 Neighboring gene uncharacterized LOC107985301 Neighboring gene signal induced proliferation associated 1 like 3 Neighboring gene uncharacterized LOC105372396 Neighboring gene small nucleolar RNA, C/D box 152

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ52608

General protein information

Preferred Names
WD repeat-containing protein 87
Names
testis development protein NYD-SP11

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001291088.2NP_001278017.1  WD repeat-containing protein 87 isoform 1

    See identical proteins and their annotated locations for NP_001278017.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1)
    Source sequence(s)
    ABBA01040648, AC016582, AK302913
    Consensus CDS
    CCDS74356.1
    UniProtKB/TrEMBL
    B4DZG8, E7ESW6
    Related
    ENSP00000405012.2, ENST00000447313.7
    Conserved Domains (6) summary
    COG1340
    Location:16281920
    COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
    COG2319
    Location:251646
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:202238
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:252531
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cl15838
    Location:16211744
    Phage_GPO; Phage capsid scaffolding protein (GPO) serine peptidase
    cl19219
    Location:18341920
    DUF342; Protein of unknown function (DUF342)
  2. NM_031951.5NP_114157.4  WD repeat-containing protein 87 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
    Source sequence(s)
    ABBA01040648, AC016582, AK128826, HY010892
    Consensus CDS
    CCDS46063.1
    UniProtKB/Swiss-Prot
    Q6ZQQ6
    Related
    ENSP00000368025.3, ENST00000303868.5
    Conserved Domains (6) summary
    COG1340
    Location:15891881
    COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
    COG2319
    Location:212607
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:163199
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:213492
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cl15838
    Location:15821705
    Phage_GPO; Phage capsid scaffolding protein (GPO) serine peptidase
    cl19219
    Location:17951881
    DUF342; Protein of unknown function (DUF342)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    37884577..37906617 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011527360.2XP_011525662.1  WD repeat-containing protein 87 isoform X1

    See identical proteins and their annotated locations for XP_011525662.1

    UniProtKB/TrEMBL
    E7ESW6
    Conserved Domains (6) summary
    COG1340
    Location:16281920
    COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
    COG2319
    Location:251646
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:202238
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:252531
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cl15838
    Location:16211744
    Phage_GPO; Phage capsid scaffolding protein (GPO) serine peptidase
    cl19219
    Location:18341920
    DUF342; Protein of unknown function (DUF342)
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