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TSPAN10 tetraspanin 10 [ Homo sapiens (human) ]

Gene ID: 83882, updated on 25-Aug-2020

Summary

Official Symbol
TSPAN10provided by HGNC
Official Full Name
tetraspanin 10provided by HGNC
Primary source
HGNC:HGNC:29942
See related
Ensembl:ENSG00000182612
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OCSP
Expression
Low expression observed in reference dataset See more
Orthologs

Genomic context

See TSPAN10 in Genome Data Viewer
Location:
17q25.3
Exon count:
5
Annotation release Status Assembly Chr Location
109.20200815 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (81637196..81648755)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (79609349..79615779)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene FA core complex associated protein 100 Neighboring gene NPL4 homolog, ubiquitin recognition factor Neighboring gene phosphodiesterase 6G Neighboring gene oxidoreductase like domain containing 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ39607

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enzyme binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
establishment of protein localization to organelle IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
tetraspanin-10
Names
oculospanin
tspan-10

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001290212.2NP_001277141.2  tetraspanin-10 isoform a

    Status: VALIDATED

    Source sequence(s)
    AB593081, AB593082, AC139530, BC021923, DA626003
    Consensus CDS
    CCDS77130.1
    Related
    ENSP00000484664.1, ENST00000611590.1
  2. NM_031945.5NP_114151.3  tetraspanin-10 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and initiates translation at a downstream in-frame start codon, compared to variant 1. The encoded isoform (b) is shorter at the N-terminus, compared to isoform a.
    Source sequence(s)
    AC139530, KF459694
    UniProtKB/Swiss-Prot
    Q9H1Z9
    UniProtKB/TrEMBL
    A0A087X235, F1T0E8, Q6PJ65
    Conserved Domains (2) summary
    cd03167
    Location:172291
    oculospanin_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), oculospanin_like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment ...
    pfam00335
    Location:75305
    Tetraspannin; Tetraspanin family

RNA

  1. NR_110866.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' region and includes a additional internal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AB593082, AC139530, BC021923, BC032802, BM710905
    Related
    ENST00000621293.4

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20200815

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

    Range
    81637196..81648755
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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