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MRO maestro [ Homo sapiens (human) ]

Gene ID: 83876, updated on 23-Nov-2021

Summary

Official Symbol
MROprovided by HGNC
Official Full Name
maestroprovided by HGNC
Primary source
HGNC:HGNC:24121
See related
Ensembl:ENSG00000134042 MIM:608080
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
B29; C18orf3
Summary
This gene is specifically transcribed in males before and after differentiation of testis, and the encoded protein may play an important role in a mammalian sex determination. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Expression
Biased expression in testis (RPKM 16.9), kidney (RPKM 11.1) and 9 other tissues See more
Orthologs
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Genomic context

See MRO in Genome Data Viewer
Location:
18q21.2
Exon count:
10
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 18 NC_000018.10 (50795130..50825413, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 18 NC_000018.9 (48321500..48351750, complement)

Chromosome 18 - NC_000018.10Genomic Context describing neighboring genes Neighboring gene mitogen-activated protein kinase 4 Neighboring gene uncharacterized LOC105372116 Neighboring gene heterogeneous nuclear ribonucleoprotein A3 pseudogene 16 Neighboring gene ribosomal protein L17 pseudogene 46 Neighboring gene malic enzyme 2 Neighboring gene uncharacterized LOC107985152 Neighboring gene elaC ribonuclease Z 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

General gene information

Markers

Homology

Clone Names

  • FLJ30140

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
protein maestro
Names
beside the Ma29 deletion
male-specific transcription in the developing reproductive organs

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001127174.3NP_001120646.1  protein maestro isoform b

    See identical proteins and their annotated locations for NP_001120646.1

    Status: REVIEWED

    Source sequence(s)
    AC015864
    Consensus CDS
    CCDS45869.1
    UniProtKB/Swiss-Prot
    Q9BYG7
    Related
    ENSP00000465653.1, ENST00000588444.5
  2. NM_001127175.3NP_001120647.1  protein maestro isoform c

    Status: REVIEWED

    Source sequence(s)
    AC015864
    Consensus CDS
    CCDS45867.1
    UniProtKB/Swiss-Prot
    Q9BYG7
    Related
    ENSP00000392614.1, ENST00000431965.6
  3. NM_001127176.3NP_001120648.1  protein maestro isoform d

    Status: REVIEWED

    Source sequence(s)
    AC015864
    Consensus CDS
    CCDS45868.1
    UniProtKB/Swiss-Prot
    Q9BYG7
    Related
    ENSP00000397900.1, ENST00000436348.6
  4. NM_001369508.2NP_001356437.1  protein maestro isoform a

    Status: REVIEWED

    Source sequence(s)
    AC015864
    Related
    ENSP00000256425.2, ENST00000256425.6
  5. NM_001369510.2NP_001356439.1  protein maestro isoform a

    Status: REVIEWED

    Source sequence(s)
    AC015864
  6. NM_001369511.2NP_001356440.1  protein maestro isoform b

    Status: REVIEWED

    Source sequence(s)
    AC015864
  7. NM_001369515.2NP_001356444.1  protein maestro isoform b

    Status: REVIEWED

    Source sequence(s)
    AC015864
  8. NM_031939.6NP_114145.2  protein maestro isoform a

    See identical proteins and their annotated locations for NP_114145.2

    Status: REVIEWED

    Source sequence(s)
    AC015864
    Consensus CDS
    CCDS11947.1
    UniProtKB/Swiss-Prot
    Q9BYG7
    UniProtKB/TrEMBL
    A0A024R2B7
    Related
    ENSP00000381465.2, ENST00000398439.8

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000018.10 Reference GRCh38.p13 Primary Assembly

    Range
    50795130..50825413 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011526226.3XP_011524528.1  protein maestro isoform X2

    See identical proteins and their annotated locations for XP_011524528.1

    UniProtKB/Swiss-Prot
    Q9BYG7
    Related
    ENSP00000467427.1, ENST00000592966.5
  2. XM_017026035.2XP_016881524.1  protein maestro isoform X1

    UniProtKB/Swiss-Prot
    Q9BYG7
    UniProtKB/TrEMBL
    A0A024R2B7
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