U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

ABCI14 trigalactosyldiacylglycerol 1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 838568, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
ABCI14
Official Full Name
trigalactosyldiacylglycerol 1
Primary source
TAIR:AT1G19800
Locus tag
AT1G19800
See related
Araport:AT1G19800
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATP-binding cassette I14; F14P1.27; F14P1_27; TGD1; trigalactosyldiacylglycerol 1
Summary
Encodes a permease-like protein involved in lipid transfer from the ER to the chloroplast, more specifically, transfer of phosphatidate across the chloroplast inner membrane. Mutant leaves accumulate trigalactosyldiacylglycerol, triacylglycerol and phosphatidate. Chloroplast lipids are altered in their fatty acid composition and as a consequence the development of chloroplasts in the mutants are impacted. The mutant seeds has a higher abortion rate. Mutations in this gene suppress the low temperature-induced phenotype of Arabidopsis tocopherol-deficient mutant vte2.
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See ABCI14 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
4
Sequence:
Chromosome: 1; NC_003070.9 (6846338..6848128)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene purine permease 14 Neighboring gene cyclic nucleotide gated channel 8 Neighboring gene SHI-related sequence 7 Neighboring gene miscRNA Neighboring gene SAUR-like auxin-responsive protein family

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Mutation of the TGD1 chloroplast envelope protein affects phosphatidate metabolism in Arabidopsis. Xu C, et al. Plant Cell, 2005 Nov. PMID 16199613, Free PMC Article
  2. TGD1, -2, and -3 proteins involved in lipid trafficking form ATP-binding cassette (ABC) transporter with multiple substrate-binding proteins. Roston RL, et al. J Biol Chem, 2012 Jun 15. PMID 22544736, Free PMC Article
  3. Genetic analysis of Arabidopsis mutants impaired in plastid lipid import reveals a role of membrane lipids in chloroplast division. Fan J, et al. Plant Signal Behav, 2011 Mar. PMID 21358271, Free PMC Article
  4. A small ATPase protein of Arabidopsis, TGD3, involved in chloroplast lipid import. Lu B, et al. J Biol Chem, 2007 Dec 7. PMID 17938172
  5. Arabidopsis TRIGALACTOSYLDIACYLGLYCEROL5 Interacts with TGD1, TGD2, and TGD4 to Facilitate Lipid Transfer from the Endoplasmic Reticulum to Plastids. Fan J, et al. Plant Cell, 2015 Oct. PMID 26410300, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. TGD1, -2, and -3 proteins involved in lipid trafficking form ATP-binding cassette (ABC) transporter with multiple substrate-binding proteins.
    Title: TGD1, -2, and -3 proteins involved in lipid trafficking form ATP-binding cassette (ABC) transporter with multiple substrate-binding proteins.
  2. The tgd1-1 fad6 and tgd4-3 fad6 double mutants were deficient in polyunsaturated fatty acids in chloroplast membrane lipids, and severely compromised in the biogenesis of photosynthetic membrane systems.
    Title: Genetic analysis of Arabidopsis mutants impaired in plastid lipid import reveals a role of membrane lipids in chloroplast division.
  3. TGD3 is the missing ATPase component of a lipid transporter involving TGD1 and TGD2 required for the biosynthesis of ER-derived thylakoid lipids in Arabidopsis.
    Title: A small ATPase protein of Arabidopsis, TGD3, involved in chloroplast lipid import.
  4. As even partial disruption of TGD1 function has drastic consequences on central lipid metabolism, the tgd1 mutant provides a tool to explore regulatory mechanisms governing lipid homeostasis and lipid trafficking in plants.
    Title: Mutation of the TGD1 chloroplast envelope protein affects phosphatidate metabolism in Arabidopsis.
Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

NM_001332407.1
NM_001332408.1
NM_001332409.1
NM_101836.4
NM_202139.3
NM_202140.2

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables lipid transporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within lipid transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of ATP-binding cassette (ABC) transporter complex IEA
Inferred from Electronic Annotation
more info
  
located_in chloroplast HDA PubMed 
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in chloroplast envelope HDA PubMed 
located_in chloroplast envelope IDA
Inferred from Direct Assay
more info
 PubMed 
located_in chloroplast inner membrane TAS
Traceable Author Statement
more info
 PubMed 
located_in chloroplast outer membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus HDA PubMed 

General protein information

Go to the top of the page Help
Preferred Names
trigalactosyldiacylglycerol 1
NP_173410.1
  • trigalactosyldiacylglycerol 1 (TGD1); FUNCTIONS IN: lipid transporter activity; INVOLVED IN: lipid transport; LOCATED IN: chloroplast outer membrane, chloroplast, chloroplast inner membrane, chloroplast envelope; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF140 (InterPro:IPR003453); Has 5322 Blast hits to 5322 proteins in 1401 species: Archae - 0; Bacteria - 4515; Metazoa - 1; Fungi - 0; Plants - 48; Viruses - 0; Other Eukaryotes - 758 (source: NCBI BLink).
NP_973868.1
  • trigalactosyldiacylglycerol 1 (TGD1); FUNCTIONS IN: lipid transporter activity; INVOLVED IN: lipid transport; LOCATED IN: chloroplast outer membrane, chloroplast, chloroplast inner membrane, chloroplast envelope; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF140 (InterPro:IPR003453); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
NP_973869.1
  • trigalactosyldiacylglycerol 1 (TGD1); FUNCTIONS IN: lipid transporter activity; INVOLVED IN: lipid transport; LOCATED IN: chloroplast outer membrane, chloroplast, chloroplast inner membrane, chloroplast envelope; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF140 (InterPro:IPR003453); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    6846338..6848128
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_202140.2 → NP_973869.1  trigalactosyldiacylglycerol 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_973869.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8L4R0, Q9FXH8
    UniProtKB/TrEMBL
    A0A178WKD3, A0A5S9V6M4
    Conserved Domains (1) summary
    PLN03100
    Location:50 → 341
    PLN03100; Permease subunit of ER-derived-lipid transporter; Provisional

  2. NM_101836.4 → NP_173410.1  trigalactosyldiacylglycerol 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_173410.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8L4R0, Q9FXH8
    UniProtKB/TrEMBL
    A0A178WKD3, A0A5S9V6M4
    Conserved Domains (1) summary
    PLN03100
    Location:50 → 341
    PLN03100; Permease subunit of ER-derived-lipid transporter; Provisional

  3. NM_001332407.1 → NP_001322722.1  trigalactosyldiacylglycerol 1 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8L4R0, Q9FXH8
    UniProtKB/TrEMBL
    A0A178WKD3, A0A5S9V6M4
    Conserved Domains (1) summary
    PLN03100
    Location:50 → 341
    PLN03100; Permease subunit of ER-derived-lipid transporter; Provisional

  4. NM_001332408.1 → NP_001322720.1  trigalactosyldiacylglycerol 1 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8L4R0, Q9FXH8
    UniProtKB/TrEMBL
    A0A178WKD3, A0A5S9V6M4
    Conserved Domains (1) summary
    PLN03100
    Location:50 → 341
    PLN03100; Permease subunit of ER-derived-lipid transporter; Provisional

  5. NM_001332409.1 → NP_001322721.1  trigalactosyldiacylglycerol 1 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8L4R0, Q9FXH8
    UniProtKB/TrEMBL
    A0A178WKD3, A0A5S9V6M4
    Conserved Domains (1) summary
    PLN03100
    Location:50 → 341
    PLN03100; Permease subunit of ER-derived-lipid transporter; Provisional

  6. NM_202139.3 → NP_973868.1  trigalactosyldiacylglycerol 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_973868.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8L4R0, Q9FXH8
    UniProtKB/TrEMBL
    A0A178WKD3, A0A5S9V6M4
    Conserved Domains (1) summary
    PLN03100
    Location:50 → 341
    PLN03100; Permease subunit of ER-derived-lipid transporter; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8L4R0.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools