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Vegfa vascular endothelial growth factor A [ Rattus norvegicus (Norway rat) ]

Gene ID: 83785, updated on 6-Jan-2019

Summary

Official Symbol
Vegfaprovided by RGD
Official Full Name
vascular endothelial growth factor Aprovided by RGD
Primary source
RGD:619991
See related
Ensembl:ENSRNOG00000019598
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
VPF; Vegf; VEGF-A; VEGF111; VEGF164
Summary
This gene is a member of the PDGF/VEGF growth factor family. It encodes a heparin-binding protein, which exists as a disulfide-linked homodimer. This growth factor induces proliferation and migration of vascular endothelial cells, and is essential for both physiological and pathological angiogenesis. Disruption of this gene in mice resulted in abnormal embryonic blood vessel formation. This gene is upregulated in many known tumors and its expression is correlated with tumor stage and progression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. There is also evidence for alternative translation initiation from upstream non-AUG (CUG) codons resulting in additional isoforms. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is antiangiogenic. Expression of some isoforms derived from the AUG start codon is regulated by a small upstream open reading frame, which is located within an internal ribosome entry site. [provided by RefSeq, Nov 2015]
Expression
Biased expression in Lung (RPKM 1035.8), Heart (RPKM 646.4) and 8 other tissues See more
Orthologs

Genomic context

See Vegfa in Genome Data Viewer
Location:
9q12
Exon count:
8
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (17340341..17355681)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 9 NC_005108.3 (16232415..16247658)

Chromosome 9 - NC_005108.4Genomic Context describing neighboring genes Neighboring gene radial spoke head 9 homolog Neighboring gene mitochondrial ribosomal protein S18A Neighboring gene uncharacterized LOC108351891 Neighboring gene uncharacterized LOC102550162 Neighboring gene 40S ribosomal protein S29 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

  • AGE-RAGE signaling pathway in diabetic complications, organism-specific biosystem (from KEGG)
    AGE-RAGE signaling pathway in diabetic complications, organism-specific biosystemAdvanced glycation end products (AGEs) are a complex group of compounds produced through the non-enzymatic glycation and oxidation of proteins, lipids and nucleic acids, primarily due to aging and un...
  • AGE-RAGE signaling pathway in diabetic complications, conserved biosystem (from KEGG)
    AGE-RAGE signaling pathway in diabetic complications, conserved biosystemAdvanced glycation end products (AGEs) are a complex group of compounds produced through the non-enzymatic glycation and oxidation of proteins, lipids and nucleic acids, primarily due to aging and un...
  • Axon guidance, organism-specific biosystem (from REACTOME)
    Axon guidance, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • Bladder cancer, organism-specific biosystem (from KEGG)
    Bladder cancer, organism-specific biosystemThe urothelium covers the luminal surface of almost the entire urinary tract, extending from the renal pelvis, through the ureter and bladder, to the proximal urethra. The majority of urothelial carc...
  • Bladder cancer, conserved biosystem (from KEGG)
    Bladder cancer, conserved biosystemThe urothelium covers the luminal surface of almost the entire urinary tract, extending from the renal pelvis, through the ureter and bladder, to the proximal urethra. The majority of urothelial carc...
  • Cytokine-cytokine receptor interaction, organism-specific biosystem (from KEGG)
    Cytokine-cytokine receptor interaction, organism-specific biosystemCytokines are soluble extracellular proteins or glycoproteins that are crucial intercellular regulators and mobilizers of cells engaged in innate as well as adaptive inflammatory host defenses, cell ...
  • Cytokine-cytokine receptor interaction, conserved biosystem (from KEGG)
    Cytokine-cytokine receptor interaction, conserved biosystemCytokines are soluble extracellular proteins or glycoproteins that are crucial intercellular regulators and mobilizers of cells engaged in innate as well as adaptive inflammatory host defenses, cell ...
  • Developmental Biology, organism-specific biosystem (from REACTOME)
    Developmental Biology, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • EGFR tyrosine kinase inhibitor resistance, organism-specific biosystem (from KEGG)
    EGFR tyrosine kinase inhibitor resistance, organism-specific biosystemEGFR is a tyrosine kinase that participates in the regulation of cellular homeostasis. EGFR also serves as a stimulus for cancer growth. EGFR gene mutations and protein overexpression, both of which ...
  • EGFR tyrosine kinase inhibitor resistance, conserved biosystem (from KEGG)
    EGFR tyrosine kinase inhibitor resistance, conserved biosystemEGFR is a tyrosine kinase that participates in the regulation of cellular homeostasis. EGFR also serves as a stimulus for cancer growth. EGFR gene mutations and protein overexpression, both of which ...
  • EPH-Ephrin signaling, organism-specific biosystem (from REACTOME)
    EPH-Ephrin signaling, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • EPHA-mediated growth cone collapse, organism-specific biosystem (from REACTOME)
    EPHA-mediated growth cone collapse, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • Endochondral Ossification, organism-specific biosystem (from WikiPathways)
    Endochondral Ossification, organism-specific biosystem
    Endochondral Ossification
  • Fluid shear stress and atherosclerosis, organism-specific biosystem (from KEGG)
    Fluid shear stress and atherosclerosis, organism-specific biosystemShear stress represents the frictional force that the flow of blood exerts at the endothelial surface of the vessel wall and plays a central role in vascular biology and contributes to the progress o...
  • Fluid shear stress and atherosclerosis, conserved biosystem (from KEGG)
    Fluid shear stress and atherosclerosis, conserved biosystemShear stress represents the frictional force that the flow of blood exerts at the endothelial surface of the vessel wall and plays a central role in vascular biology and contributes to the progress o...
  • Focal Adhesion, organism-specific biosystem (from WikiPathways)
    Focal Adhesion, organism-specific biosystemCell-matrix adhesions play essential roles in important biological processes including cell motility, cell proliferation, cell differentiation, regulation of gene expression and cell survival. At the...
  • Focal adhesion, organism-specific biosystem (from KEGG)
    Focal adhesion, organism-specific biosystemCell-matrix adhesions play essential roles in important biological processes including cell motility, cell proliferation, cell differentiation, regulation of gene expression and cell survival. At the...
  • Focal adhesion, conserved biosystem (from KEGG)
    Focal adhesion, conserved biosystemCell-matrix adhesions play essential roles in important biological processes including cell motility, cell proliferation, cell differentiation, regulation of gene expression and cell survival. At the...
  • HIF-1 signaling pathway, organism-specific biosystem (from KEGG)
    HIF-1 signaling pathway, organism-specific biosystemHypoxia-inducible factor 1 (HIF-1) is a transcription factor that functions as a master regulator of oxygen homeostasis. It consists of two subunits: an inducibly-expressed HIF-1alpha subunit and a c...
  • Hemostasis, organism-specific biosystem (from REACTOME)
    Hemostasis, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • Hypertrophy Model, organism-specific biosystem (from WikiPathways)
    Hypertrophy Model, organism-specific biosystem
    Hypertrophy Model
  • Id Signaling Pathway, organism-specific biosystem (from WikiPathways)
    Id Signaling Pathway, organism-specific biosystemInhibitor of DNA binding (ID) proteins are members of the helix-loop-helix (HLH) family of proteins which lack a DNA binding domain themselves but bind to other family members inhibiting their DNA bi...
  • MicroRNAs in cancer, organism-specific biosystem (from KEGG)
    MicroRNAs in cancer, organism-specific biosystemMicroRNA (miRNA) is a cluster of small non-encoding RNA molecules of 21 - 23 nucleotides in length, which controls gene expression post-transcriptionally either via the degradation of target mRNAs or...
  • MicroRNAs in cancer, conserved biosystem (from KEGG)
    MicroRNAs in cancer, conserved biosystemMicroRNA (miRNA) is a cluster of small non-encoding RNA molecules of 21 - 23 nucleotides in length, which controls gene expression post-transcriptionally either via the degradation of target mRNAs or...
  • PI3K-Akt signaling pathway, organism-specific biosystem (from KEGG)
    PI3K-Akt signaling pathway, organism-specific biosystemThe phosphatidylinositol 3' -kinase(PI3K)-Akt signaling pathway is activated by many types of cellular stimuli or toxic insults and regulates fundamental cellular functions such as transcription, tra...
  • PI3K-Akt signaling pathway, conserved biosystem (from KEGG)
    PI3K-Akt signaling pathway, conserved biosystemThe phosphatidylinositol 3' -kinase(PI3K)-Akt signaling pathway is activated by many types of cellular stimuli or toxic insults and regulates fundamental cellular functions such as transcription, tra...
  • Pancreatic cancer, organism-specific biosystem (from KEGG)
    Pancreatic cancer, organism-specific biosystemInfiltrating ductal adenocarcinoma is the most common malignancy of the pancreas. When most investigators use the term 'pancreatic cancer' they are referring to pancreatic ductal adenocarcinoma (PDA)...
  • Pancreatic cancer, conserved biosystem (from KEGG)
    Pancreatic cancer, conserved biosystemInfiltrating ductal adenocarcinoma is the most common malignancy of the pancreas. When most investigators use the term 'pancreatic cancer' they are referring to pancreatic ductal adenocarcinoma (PDA)...
  • Pathways in cancer, organism-specific biosystem (from KEGG)
    Pathways in cancer, organism-specific biosystem
    Pathways in cancer
  • Platelet activation, signaling and aggregation, organism-specific biosystem (from REACTOME)
    Platelet activation, signaling and aggregation, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • Platelet degranulation, organism-specific biosystem (from REACTOME)
    Platelet degranulation, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • Proteoglycans in cancer, organism-specific biosystem (from KEGG)
    Proteoglycans in cancer, organism-specific biosystemMany proteoglycans (PGs) in the tumor microenvironment have been shown to be key macromolecules that contribute to biology of various types of cancer including proliferation, adhesion, angiogenesis a...
  • Proteoglycans in cancer, conserved biosystem (from KEGG)
    Proteoglycans in cancer, conserved biosystemMany proteoglycans (PGs) in the tumor microenvironment have been shown to be key macromolecules that contribute to biology of various types of cancer including proliferation, adhesion, angiogenesis a...
  • Rap1 signaling pathway, organism-specific biosystem (from KEGG)
    Rap1 signaling pathway, organism-specific biosystemRap1 is a small GTPase that controls diverse processes, such as cell adhesion, cell-cell junction formation and cell polarity. Like all G proteins, Rap1 cycles between an inactive GDP-bound and an ac...
  • Rap1 signaling pathway, conserved biosystem (from KEGG)
    Rap1 signaling pathway, conserved biosystemRap1 is a small GTPase that controls diverse processes, such as cell adhesion, cell-cell junction formation and cell polarity. Like all G proteins, Rap1 cycles between an inactive GDP-bound and an ac...
  • Ras signaling pathway, organism-specific biosystem (from KEGG)
    Ras signaling pathway, organism-specific biosystemThe Ras proteins are GTPases that function as molecular switches for signaling pathways regulating cell proliferation, survival, growth, migration, differentiation or cytoskeletal dynamism. Ras prote...
  • Renal cell carcinoma, organism-specific biosystem (from KEGG)
    Renal cell carcinoma, organism-specific biosystemRenal cell cancer (RCC) accounts for ~3% of human malignancies and its incidence appears to be rising. Although most cases of RCC seem to occur sporadically, an inherited predisposition to renal canc...
  • Renal cell carcinoma, conserved biosystem (from KEGG)
    Renal cell carcinoma, conserved biosystemRenal cell cancer (RCC) accounts for ~3% of human malignancies and its incidence appears to be rising. Although most cases of RCC seem to occur sporadically, an inherited predisposition to renal canc...
  • Response to elevated platelet cytosolic Ca2+, organism-specific biosystem (from REACTOME)
    Response to elevated platelet cytosolic Ca2+, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • Rheumatoid arthritis, organism-specific biosystem (from KEGG)
    Rheumatoid arthritis, organism-specific biosystemRheumatoid arthritis (RA) is a chronic autoimmune joint disease where persistent inflammation affects bone remodeling leading to progressive bone destruction. In RA, abnormal activation of the immune...
  • Rheumatoid arthritis, conserved biosystem (from KEGG)
    Rheumatoid arthritis, conserved biosystemRheumatoid arthritis (RA) is a chronic autoimmune joint disease where persistent inflammation affects bone remodeling leading to progressive bone destruction. In RA, abnormal activation of the immune...
  • Signal Transduction, organism-specific biosystem (from REACTOME)
    Signal Transduction, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • Signaling by VEGF, organism-specific biosystem (from REACTOME)
    Signaling by VEGF, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • VEGF binds to VEGFR leading to receptor dimerization, organism-specific biosystem (from REACTOME)
    VEGF binds to VEGFR leading to receptor dimerization, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • VEGF ligand-receptor interactions, organism-specific biosystem (from REACTOME)
    VEGF ligand-receptor interactions, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • VEGF signaling pathway, organism-specific biosystem (from KEGG)
    VEGF signaling pathway, organism-specific biosystemThere is now much evidence that VEGFR-2 is the major mediator of VEGF-driven responses in endothelial cells and it is considered to be a crucial signal transducer in both physiologic and pathologic a...
  • VEGF signaling pathway, conserved biosystem (from KEGG)
    VEGF signaling pathway, conserved biosystemThere is now much evidence that VEGFR-2 is the major mediator of VEGF-driven responses in endothelial cells and it is considered to be a crucial signal transducer in both physiologic and pathologic a...
  • VEGF-receptor Signal Transduction, organism-specific biosystem (from WikiPathways)
    VEGF-receptor Signal Transduction, organism-specific biosystemVEGF Signal transduction in haematopoeitic stem cells, macrophages, monocyten, vascular endothelium and lymphatic endothelium.
  • VEGFA-VEGFR2 Pathway, organism-specific biosystem (from REACTOME)
    VEGFA-VEGFR2 Pathway, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • VEGFR2 mediated cell proliferation, organism-specific biosystem (from REACTOME)
    VEGFR2 mediated cell proliferation, organism-specific biosystemcomputationally inferred pathway (not manually curated)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
chemoattractant activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
chemoattractant activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
chemoattractant activity ISO
Inferred from Sequence Orthology
more info
 
cytokine activity ISO
Inferred from Sequence Orthology
more info
 
extracellular matrix binding ISO
Inferred from Sequence Orthology
more info
 
fibronectin binding ISO
Inferred from Sequence Orthology
more info
 
growth factor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
growth factor activity IDA
Inferred from Direct Assay
more info
PubMed 
growth factor activity IEA
Inferred from Electronic Annotation
more info
 
growth factor activity ISO
Inferred from Sequence Orthology
more info
 
growth factor binding IPI
Inferred from Physical Interaction
more info
PubMed 
heparin binding IEA
Inferred from Electronic Annotation
more info
 
heparin binding ISO
Inferred from Sequence Orthology
more info
 
identical protein binding ISO
Inferred from Sequence Orthology
more info
 
neuropilin binding ISO
Inferred from Sequence Orthology
more info
 
platelet-derived growth factor receptor binding ISO
Inferred from Sequence Orthology
more info
 
protein heterodimerization activity ISO
Inferred from Sequence Orthology
more info
 
protein homodimerization activity IDA
Inferred from Direct Assay
more info
PubMed 
receptor ligand activity ISO
Inferred from Sequence Orthology
more info
 
signaling receptor binding ISO
Inferred from Sequence Orthology
more info
 
vascular endothelial growth factor receptor 1 binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
vascular endothelial growth factor receptor 1 binding ISO
Inferred from Sequence Orthology
more info
 
vascular endothelial growth factor receptor 2 binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
vascular endothelial growth factor receptor 2 binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
vascular endothelial growth factor receptor 2 binding ISO
Inferred from Sequence Orthology
more info
 
vascular endothelial growth factor receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
vascular endothelial growth factor receptor binding ISO
Inferred from Sequence Orthology
more info
 
vascular endothelial growth factor receptor binding TAS
Traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
T-helper 1 type immune response IDA
Inferred from Direct Assay
more info
PubMed 
VEGF-activated neuropilin signaling pathway ISO
Inferred from Sequence Orthology
more info
 
activation of protein kinase activity ISO
Inferred from Sequence Orthology
more info
 
aging IEP
Inferred from Expression Pattern
more info
PubMed 
angiogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
angiogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
angiogenesis ISO
Inferred from Sequence Orthology
more info
 
angiogenesis TAS
Traceable Author Statement
more info
PubMed 
angiogenesis involved in coronary vascular morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
artery morphogenesis ISO
Inferred from Sequence Orthology
more info
 
basophil chemotaxis ISO
Inferred from Sequence Orthology
more info
 
blood vessel development ISO
Inferred from Sequence Orthology
more info
 
blood vessel endothelial cell proliferation involved in sprouting angiogenesis ISO
Inferred from Sequence Orthology
more info
 
blood vessel morphogenesis ISO
Inferred from Sequence Orthology
more info
 
blood vessel remodeling IMP
Inferred from Mutant Phenotype
more info
PubMed 
bone trabecula formation ISO
Inferred from Sequence Orthology
more info
 
bone trabecula morphogenesis ISO
Inferred from Sequence Orthology
more info
 
branching involved in blood vessel morphogenesis ISO
Inferred from Sequence Orthology
more info
 
branching morphogenesis of an epithelial tube ISO
Inferred from Sequence Orthology
more info
 
camera-type eye morphogenesis ISO
Inferred from Sequence Orthology
more info
 
cardiac muscle fiber development ISO
Inferred from Sequence Orthology
more info
 
cardiac vascular smooth muscle cell development ISO
Inferred from Sequence Orthology
more info
 
cell chemotaxis IMP
Inferred from Mutant Phenotype
more info
PubMed 
cell maturation ISO
Inferred from Sequence Orthology
more info
 
cell migration ISO
Inferred from Sequence Orthology
more info
 
cell migration involved in sprouting angiogenesis ISO
Inferred from Sequence Orthology
more info
 
cell proliferation ISO
Inferred from Sequence Orthology
more info
 
cellular response to dexamethasone stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
cellular response to drug IEP
Inferred from Expression Pattern
more info
PubMed 
cellular response to fibroblast growth factor stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
cellular response to hypoxia ISO
Inferred from Sequence Orthology
more info
 
cellular response to vascular endothelial growth factor stimulus ISO
Inferred from Sequence Orthology
more info
 
cellular stress response to acid chemical ISO
Inferred from Sequence Orthology
more info
 
commissural neuron axon guidance ISO
Inferred from Sequence Orthology
more info
 
NOT commissural neuron axon guidance ISO
Inferred from Sequence Orthology
more info
 
coronary artery morphogenesis ISO
Inferred from Sequence Orthology
more info
 
coronary vein morphogenesis ISO
Inferred from Sequence Orthology
more info
 
dopaminergic neuron differentiation ISO
Inferred from Sequence Orthology
more info
 
endothelial cell chemotaxis ISO
Inferred from Sequence Orthology
more info
 
endothelial cell migration ISO
Inferred from Sequence Orthology
more info
 
epithelial cell differentiation ISO
Inferred from Sequence Orthology
more info
 
eye photoreceptor cell development ISO
Inferred from Sequence Orthology
more info
 
female pregnancy IEP
Inferred from Expression Pattern
more info
PubMed 
heart morphogenesis ISO
Inferred from Sequence Orthology
more info
 
homeostasis of number of cells within a tissue ISO
Inferred from Sequence Orthology
more info
 
hyaluronan metabolic process IEP
Inferred from Expression Pattern
more info
PubMed 
in utero embryonic development ISO
Inferred from Sequence Orthology
more info
 
induction of positive chemotaxis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
induction of positive chemotaxis ISO
Inferred from Sequence Orthology
more info
 
kidney development ISO
Inferred from Sequence Orthology
more info
 
lactation ISO
Inferred from Sequence Orthology
more info
 
lung alveolus development IMP
Inferred from Mutant Phenotype
more info
PubMed 
lung development ISO
Inferred from Sequence Orthology
more info
 
lung vasculature development ISO
Inferred from Sequence Orthology
more info
 
lymph vessel morphogenesis ISO
Inferred from Sequence Orthology
more info
 
lymphangiogenesis ISO
Inferred from Sequence Orthology
more info
 
mRNA stabilization IDA
Inferred from Direct Assay
more info
PubMed 
macrophage differentiation ISO
Inferred from Sequence Orthology
more info
 
mammary gland alveolus development ISO
Inferred from Sequence Orthology
more info
 
mesoderm development ISO
Inferred from Sequence Orthology
more info
 
monocyte differentiation ISO
Inferred from Sequence Orthology
more info
 
motor neuron migration ISO
Inferred from Sequence Orthology
more info
 
motor neuron migration ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
 
negative regulation of bone resorption IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of cell-cell adhesion ISO
Inferred from Sequence Orthology
more info
 
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process ISO
Inferred from Sequence Orthology
more info
 
negative regulation of epithelial to mesenchymal transition ISO
Inferred from Sequence Orthology
more info
 
negative regulation of extrinsic apoptotic signaling pathway ISO
Inferred from Sequence Orthology
more info
 
negative regulation of fat cell differentiation ISO
Inferred from Sequence Orthology
more info
 
negative regulation of gene expression ISO
Inferred from Sequence Orthology
more info
 
negative regulation of neuron apoptotic process ISO
Inferred from Sequence Orthology
more info
 
negative regulation of neuron death IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of programmed cell death IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
nervous system development IDA
Inferred from Direct Assay
more info
PubMed 
nervous system development NAS
Non-traceable Author Statement
more info
PubMed 
neuron development ISO
Inferred from Sequence Orthology
more info
 
outflow tract morphogenesis ISO
Inferred from Sequence Orthology
more info
 
ovarian follicle development ISO
Inferred from Sequence Orthology
more info
 
positive chemotaxis IEA
Inferred from Electronic Annotation
more info
 
positive chemotaxis ISO
Inferred from Sequence Orthology
more info
 
positive regulation of CREB transcription factor activity ISO
Inferred from Sequence Orthology
more info
 
positive regulation of DNA biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
positive regulation of ERK1 and ERK2 cascade ISO
Inferred from Sequence Orthology
more info
 
positive regulation of MAP kinase activity ISO
Inferred from Sequence Orthology
more info
 
positive regulation of angiogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of angiogenesis IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of angiogenesis ISO
Inferred from Sequence Orthology
more info
 
positive regulation of angiogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of axon extension involved in axon guidance ISO
Inferred from Sequence Orthology
more info
 
NOT positive regulation of axon extension involved in axon guidance ISO
Inferred from Sequence Orthology
more info
 
positive regulation of blood vessel endothelial cell migration ISO
Inferred from Sequence Orthology
more info
 
positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis ISO
Inferred from Sequence Orthology
more info
 
positive regulation of branching involved in ureteric bud morphogenesis ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cell adhesion ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cell division IEA
Inferred from Electronic Annotation
more info
 
positive regulation of cell migration ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cell migration involved in sprouting angiogenesis ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of cell proliferation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cell proliferation TAS
Traceable Author Statement
more info
PubMed 
positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cellular component movement ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cold-induced thermogenesis ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cold-induced thermogenesis ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
positive regulation of endothelial cell migration ISO
Inferred from Sequence Orthology
more info
 
positive regulation of endothelial cell migration ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of endothelial cell proliferation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of endothelial cell proliferation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of endothelial cell proliferation ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of epithelial cell proliferation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of focal adhesion assembly ISO
Inferred from Sequence Orthology
more info
 
positive regulation of focal adhesion assembly ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of gene expression ISO
Inferred from Sequence Orthology
more info
 
positive regulation of histone deacetylase activity ISO
Inferred from Sequence Orthology
more info
 
positive regulation of lymphangiogenesis ISO
Inferred from Sequence Orthology
more info
 
positive regulation of mast cell chemotaxis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of mast cell chemotaxis ISO
Inferred from Sequence Orthology
more info
 
positive regulation of mesenchymal cell proliferation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of neuroblast proliferation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of osteoblast differentiation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of p38MAPK cascade ISO
Inferred from Sequence Orthology
more info
 
positive regulation of peptidyl-serine phosphorylation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of peptidyl-tyrosine autophosphorylation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of peptidyl-tyrosine phosphorylation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of peptidyl-tyrosine phosphorylation ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of phosphorylation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of positive chemotaxis ISO
Inferred from Sequence Orthology
more info
 
positive regulation of protein autophosphorylation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of protein complex assembly ISO
Inferred from Sequence Orthology
more info
 
positive regulation of protein complex assembly ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of protein kinase B signaling ISO
Inferred from Sequence Orthology
more info
 
positive regulation of protein kinase C signaling ISO
Inferred from Sequence Orthology
more info
 
positive regulation of protein kinase D signaling ISO
Inferred from Sequence Orthology
more info
 
positive regulation of protein localization to early endosome ISO
Inferred from Sequence Orthology
more info
 
positive regulation of protein phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of protein phosphorylation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of protein phosphorylation ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of receptor internalization ISO
Inferred from Sequence Orthology
more info
 
positive regulation of retinal ganglion cell axon guidance ISO
Inferred from Sequence Orthology
more info
 
positive regulation of signal transduction IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of smooth muscle cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of sprouting angiogenesis ISO
Inferred from Sequence Orthology
more info
 
positive regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
positive regulation of transcription from RNA polymerase II promoter in response to hypoxia ISO
Inferred from Sequence Orthology
more info
 
NOT positive regulation of tyrosine phosphorylation of STAT protein ISO
Inferred from Sequence Orthology
more info
 
positive regulation of vascular endothelial growth factor receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
positive regulation of vascular permeability IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of vascular permeability ISO
Inferred from Sequence Orthology
more info
 
post-embryonic camera-type eye development ISO
Inferred from Sequence Orthology
more info
 
primitive erythrocyte differentiation ISO
Inferred from Sequence Orthology
more info
 
regulation of cell shape ISO
Inferred from Sequence Orthology
more info
 
regulation of endothelial cell differentiation ISO
Inferred from Sequence Orthology
more info
 
regulation of growth ISO
Inferred from Sequence Orthology
more info
 
regulation of hematopoietic progenitor cell differentiation ISO
Inferred from Sequence Orthology
more info
 
regulation of nitric oxide mediated signal transduction ISO
Inferred from Sequence Orthology
more info
 
regulation of retinal ganglion cell axon guidance ISO
Inferred from Sequence Orthology
more info
 
NOT regulation of retinal ganglion cell axon guidance ISO
Inferred from Sequence Orthology
more info
 
regulation of signaling receptor activity IEA
Inferred from Electronic Annotation
more info
 
regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
response to cold IEP
Inferred from Expression Pattern
more info
PubMed 
response to dexamethasone IEP
Inferred from Expression Pattern
more info
PubMed 
response to estradiol IEP
Inferred from Expression Pattern
more info
PubMed 
response to folic acid IEP
Inferred from Expression Pattern
more info
PubMed 
response to hypoxia IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
response to hypoxia IDA
Inferred from Direct Assay
more info
PubMed 
response to hypoxia ISO
Inferred from Sequence Orthology
more info
 
response to oxygen levels IEP
Inferred from Expression Pattern
more info
PubMed 
response to progesterone IEP
Inferred from Expression Pattern
more info
PubMed 
response to vitamin A IEP
Inferred from Expression Pattern
more info
PubMed 
retinal blood vessel morphogenesis ISO
Inferred from Sequence Orthology
more info
 
sprouting angiogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
sprouting angiogenesis ISO
Inferred from Sequence Orthology
more info
 
surfactant homeostasis ISO
Inferred from Sequence Orthology
more info
 
tube formation ISO
Inferred from Sequence Orthology
more info
 
tube formation ISS
Inferred from Sequence or Structural Similarity
more info
 
vascular endothelial growth factor receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
vascular endothelial growth factor receptor signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
vascular endothelial growth factor receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
vascular endothelial growth factor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
vascular endothelial growth factor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
vasculature development ISO
Inferred from Sequence Orthology
more info
 
wound healing IEP
Inferred from Expression Pattern
more info
PubMed 
Component Evidence Code Pubs
basement membrane IDA
Inferred from Direct Assay
more info
PubMed 
cell surface ISO
Inferred from Sequence Orthology
more info
 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
extracellular region ISO
Inferred from Sequence Orthology
more info
 
extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
extracellular space IDA
Inferred from Direct Assay
more info
PubMed 
extracellular space ISO
Inferred from Sequence Orthology
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 
secretory granule ISO
Inferred from Sequence Orthology
more info
 
vesicle IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
vascular endothelial growth factor A
Names
vascular permeability factor

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001110333.2NP_001103803.1  vascular endothelial growth factor A isoform 2

    See identical proteins and their annotated locations for NP_001103803.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) lacks an in-frame, internal coding exon, compared to variant 1. This variant can initiate translation from non-AUG (CUG) site, and also from a downstream, in-frame AUG site. The isoform (2) represented in this RefSeq is derived from the CUG start codon and it lacks an internal segment, compared to isoform 1.
    Source sequence(s)
    AC108326, BC168708, CO565920
    UniProtKB/TrEMBL
    B5DEK7
    Related
    ENSRNOP00000026559.3, ENSRNOT00000026559.5
    Conserved Domains (2) summary
    smart00141
    Location:228310
    PDGF; Platelet-derived and vascular endothelial growth factors (PDGF, VEGF) family
    pfam14554
    Location:316369
    VEGF_C; VEGF heparin-binding domain
  2. NM_001110334.2NP_001103804.1  vascular endothelial growth factor A isoform 3

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) lacks two consecutive in-frame exons in the 3' coding region, compared to variant 1. This variant can initiate translation from non-AUG (CUG) site, and also from a downstream, in-frame AUG site. The isoform (3) represented in this RefSeq is derived from the CUG start codon and it lacks an internal segment, compared to isoform 1.
    Source sequence(s)
    AC108326, AF215726, BC168708, CO565920
    UniProtKB/Swiss-Prot
    P16612
    UniProtKB/TrEMBL
    B5DEK7
    Related
    ENSRNOP00000050127.2, ENSRNOT00000044163.4
    Conserved Domains (1) summary
    smart00141
    Location:228310
    PDGF; Platelet-derived and vascular endothelial growth factors (PDGF, VEGF) family
  3. NM_001110335.1NP_001103805.1  vascular endothelial growth factor A isoform 4

    See identical proteins and their annotated locations for NP_001103805.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR and lacks a portion of the 5' coding region, compared to variant 1. The resulting isoform (4) has a shorter N-terminus, compared to isoform 1. This variant has transcript support, but the protein is predicted.
    Source sequence(s)
    BQ203400, CK357826, CK358638, CK364938, CK602714, CV107730
    Conserved Domains (2) summary
    pfam14554
    Location:61109
    VEGF_C; VEGF heparin-binding domain
    cl00116
    Location:126
    PDGF; Platelet-derived and vascular endothelial growth factors (PDGF, VEGF) family domain; PDGF is a potent activator for cells of mesenchymal origin; PDGF-A and PDGF-B form AA and BB homodimers and an AB heterodimer; VEGF is a potent mitogen in embryonic and ...
  4. NM_001110336.1NP_001103806.1  vascular endothelial growth factor A isoform 5

    See identical proteins and their annotated locations for NP_001103806.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR and lacks a portion of the 5' coding region and an in-frame, internal coding exon, compared to variant 1. The resulting isoform (5) has a shorter N-terminus and lacks an internal segment, compared to isoform 1. This variant has transcript support, but the protein is predicted.
    Source sequence(s)
    BQ203400, CK357826, CK358638, CK364938, CK602714, CV107730
    Conserved Domains (2) summary
    pfam14554
    Location:3285
    VEGF_C; VEGF heparin-binding domain
    cl00116
    Location:126
    PDGF; Platelet-derived and vascular endothelial growth factors (PDGF, VEGF) family domain; PDGF is a potent activator for cells of mesenchymal origin; PDGF-A and PDGF-B form AA and BB homodimers and an AB heterodimer; VEGF is a potent mitogen in embryonic and ...
  5. NM_001287107.1NP_001274036.1  vascular endothelial growth factor A isoform 6 precursor

    See identical proteins and their annotated locations for NP_001274036.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. This variant can initiate translation from non-AUG (CUG) site, and also from a downstream, in-frame AUG site. The isoform (6) represented in this RefSeq is derived from the AUG start codon and it is shorter at the N-terminus, compared to isoform 1.
    Source sequence(s)
    AC108326, AF215725, BC168708, CO565920
    UniProtKB/Swiss-Prot
    P16612
    UniProtKB/TrEMBL
    B5DEK7
    Conserved Domains (2) summary
    smart00141
    Location:49131
    PDGF; Platelet-derived and vascular endothelial growth factors (PDGF, VEGF) family
    pfam14554
    Location:166214
    VEGF_C; VEGF heparin-binding domain
  6. NM_001287108.1NP_001274037.1  vascular endothelial growth factor A isoform Vegf-A precursor

    See identical proteins and their annotated locations for NP_001274037.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) lacks an in-frame, internal coding exon compared to variant 1. It can initiate translation from a non-AUG (CUG) codon, and also from an in-frame, downstream AUG start codon. The isoform (Vegf-A) represented in this RefSeq is derived from the AUG start codon. It has a shorter N-terminus and lacks an internal protein segment compared to isoform 1. This variant also encodes a C-terminally extended isoform (Vegf-Ax), which results from the use of an alternative in-frame, downstream translation termination codon (UAA). Isoform Vegf-Ax is represented in NM_001317043.1.
    Source sequence(s)
    AC108326, BC168708, CO565920
    UniProtKB/Swiss-Prot
    P16612
    UniProtKB/TrEMBL
    B5DEK7
    Conserved Domains (2) summary
    smart00141
    Location:49131
    PDGF; Platelet-derived and vascular endothelial growth factors (PDGF, VEGF) family
    pfam14554
    Location:137190
    VEGF_C; VEGF heparin-binding domain
  7. NM_001287110.1NP_001274039.1  vascular endothelial growth factor A isoform 8 precursor

    See identical proteins and their annotated locations for NP_001274039.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) lacks two consecutive in-frame exons in the 3' coding region, compared to variant 1. This variant can initiate translation from non-AUG (CUG) site, and also from a downstream, in-frame AUG site. The isoform (8) represented in this RefSeq is derived from the AUG start codon and it is shorter at the N-terminus and lacks an internal segment, compared to isoform 1.
    Source sequence(s)
    AC108326, AF215726, BC168708, CO565920
    UniProtKB/Swiss-Prot
    P16612
    UniProtKB/TrEMBL
    B5DEK7, Q541S7
    Conserved Domains (1) summary
    smart00141
    Location:49131
    PDGF; Platelet-derived and vascular endothelial growth factors (PDGF, VEGF) family
  8. NM_001287111.1NP_001274040.1  vascular endothelial growth factor A isoform 9

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) lacks an in-frame, internal exon in the 3' coding region, compared to variant 1. This variant can initiate translation from non-AUG (CUG) site, and also from a downstream, in-frame AUG site. The isoform (9) represented in this RefSeq is derived from the CUG start codon and it lacks an internal segment, compared to isoform 1.
    Source sequence(s)
    AC108326, AF222779, BC168708, CO565920
    UniProtKB/Swiss-Prot
    P16612
    UniProtKB/TrEMBL
    B5DEK7
    Related
    ENSRNOP00000047820.3, ENSRNOT00000042790.3
    Conserved Domains (1) summary
    smart00141
    Location:228310
    PDGF; Platelet-derived and vascular endothelial growth factors (PDGF, VEGF) family
  9. NM_001287112.1NP_001274041.1  vascular endothelial growth factor A isoform 10 precursor

    See identical proteins and their annotated locations for NP_001274041.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) lacks an in-frame, internal exon in the 3' coding region, compared to variant 1. This variant can initiate translation from non-AUG (CUG) site, and also from a downstream, in-frame AUG site. The isoform (10) represented in this RefSeq is derived from the AUG start codon and it is shorter at the N-terminus and lacks an internal segment, compared to isoform 1.
    Source sequence(s)
    AC108326, AF222779, BC168708, CO565920
    UniProtKB/Swiss-Prot
    P16612
    UniProtKB/TrEMBL
    B5DEK7
    Conserved Domains (1) summary
    smart00141
    Location:49131
    PDGF; Platelet-derived and vascular endothelial growth factors (PDGF, VEGF) family
  10. NM_001287113.1NP_001274042.1  vascular endothelial growth factor A isoform 11

    See identical proteins and their annotated locations for NP_001274042.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7) lacks an internal exon in the 5' region, which results in translation initiation at a downstream AUG site, and an in-frame, internal coding exon, compared to variant 1. The resulting isoform (11) is shorter at the N-terminus and lacks an internal segment, compared to isoform 1.
    Source sequence(s)
    AC108326, AY378102, BC168708, CO565920
    UniProtKB/TrEMBL
    A0A0G2K6Z7, B5DEK7
    Related
    ENSRNOP00000074002.1, ENSRNOT00000083811.1
    Conserved Domains (2) summary
    smart00141
    Location:789
    PDGF; Platelet-derived and vascular endothelial growth factors (PDGF, VEGF) family
    pfam14554
    Location:95148
    VEGF_C; VEGF heparin-binding domain
  11. NM_001287114.1NP_001274043.1  vascular endothelial growth factor A isoform 12

    See identical proteins and their annotated locations for NP_001274043.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (8) lacks an internal exon in the 5' region, which results in translation initiation at a downstream AUG site, and two consecutive in-frame exons in the 3' coding region, compared to variant 1. The resulting isoform (12) is shorter at the N-terminus and lacks an internal segment, compared to isoform 1.
    Source sequence(s)
    AC108326, AF215726, AY378102, BC168708, CO565920
    UniProtKB/Swiss-Prot
    P16612
    UniProtKB/TrEMBL
    B5DEK7
    Conserved Domains (1) summary
    smart00141
    Location:789
    PDGF; Platelet-derived and vascular endothelial growth factors (PDGF, VEGF) family
  12. NM_001317043.1NP_001303972.1  vascular endothelial growth factor A isoform Vegf-Ax precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) is identical to NM_001287108.1; however, it uses an alternative in-frame, downstream translation termination codon (UAA), which results in a longer, C-terminally extended isoform (Vegf-Ax) compared to isoform Vegf-A. Unlike isoform Vegf-A, which is proangiogenic, Vegf-Ax exhibits antiangiogenic activity. As the upstream UGA stop codon has been shown to be recoded as serine (PMID:24949972), its location in the Vegf-Ax isoform (aa 191) is denoted by an 'S'.
    Source sequence(s)
    AC108326, BC168708, CO565920
    UniProtKB/TrEMBL
    B5DEK7
    Conserved Domains (2) summary
    smart00141
    Location:49131
    PDGF; Platelet-derived and vascular endothelial growth factors (PDGF, VEGF) family
    pfam14554
    Location:137190
    VEGF_C; VEGF heparin-binding domain
  13. NM_031836.3NP_114024.2  vascular endothelial growth factor A isoform 1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. This variant can initiate translation from non-AUG (CUG) site, and also from a downstream, in-frame AUG site. The isoform (1) represented in this RefSeq is derived from the CUG start codon and it is the longest isoform.
    Source sequence(s)
    AC108326, AF215725, BC168708, CO565920
    UniProtKB/Swiss-Prot
    P16612
    UniProtKB/TrEMBL
    B5DEK7
    Related
    ENSRNOP00000026637.4, ENSRNOT00000026637.7
    Conserved Domains (2) summary
    smart00141
    Location:228310
    PDGF; Platelet-derived and vascular endothelial growth factors (PDGF, VEGF) family
    pfam14554
    Location:344393
    VEGF_C; VEGF heparin-binding domain

RNA

  1. NR_105011.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (9) has an alternate splice site and lacks an internal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC108326, AY702972, BC168708, CO565920

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005108.4 Reference Rnor_6.0 Primary Assembly

    Range
    17340341..17355681
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Rn_Celera

Genomic

  1. AC_000077.1 Alternate Rn_Celera

    Range
    12701425..12716765
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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