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NRIP2 nuclear receptor interacting protein 2 [ Homo sapiens (human) ]

Gene ID: 83714, updated on 23-Nov-2021

Summary

Official Symbol
NRIP2provided by HGNC
Official Full Name
nuclear receptor interacting protein 2provided by HGNC
Primary source
HGNC:HGNC:23078
See related
Ensembl:ENSG00000053702
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in kidney (RPKM 4.3), ovary (RPKM 4.3) and 25 other tissues See more
Orthologs
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Genomic context

See NRIP2 in Genome Data Viewer
Location:
12p13.33
Exon count:
8
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 12 NC_000012.12 (2825348..2835536, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (2934514..2944201, complement)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene ITFG2 antisense RNA 1 Neighboring gene chromobox 3 pseudogene 4 Neighboring gene FKBP prolyl isomerase 4 Neighboring gene integrin alpha FG-GAP repeat containing 2 Neighboring gene testis expressed 52 Neighboring gene forkhead box M1 Neighboring gene RAD9-HUS1-RAD1 interacting nuclear orphan 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • DKFZp761G1913

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables aspartic-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
nuclear receptor-interacting protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_031474.3NP_113662.1  nuclear receptor-interacting protein 2

    See identical proteins and their annotated locations for NP_113662.1

    Status: VALIDATED

    Source sequence(s)
    AL136557, BC036063, DA391605
    Consensus CDS
    CCDS8514.1
    UniProtKB/Swiss-Prot
    Q9BQI9
    Related
    ENSP00000337501.4, ENST00000337508.9
    Conserved Domains (1) summary
    cd05480
    Location:162258
    NRIP_C; NRIP_C; putative nuclear receptor interacting protein

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p13 Primary Assembly

    Range
    2825348..2835536 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017020001.1XP_016875490.1  nuclear receptor-interacting protein 2 isoform X5

  2. XM_011521031.2XP_011519333.1  nuclear receptor-interacting protein 2 isoform X4

    Conserved Domains (1) summary
    cl11403
    Location:112208
    pepsin_retropepsin_like; Cellular and retroviral pepsin-like aspartate proteases
  3. XM_005253797.4XP_005253854.1  nuclear receptor-interacting protein 2 isoform X1

    See identical proteins and their annotated locations for XP_005253854.1

    UniProtKB/Swiss-Prot
    Q9BQI9
    Conserved Domains (1) summary
    cd05480
    Location:162258
    NRIP_C; NRIP_C; putative nuclear receptor interacting protein
  4. XM_005253798.4XP_005253855.1  nuclear receptor-interacting protein 2 isoform X2

    Conserved Domains (1) summary
    cl11403
    Location:162251
    pepsin_retropepsin_like; Cellular and retroviral pepsin-like aspartate proteases
  5. XM_017020000.2XP_016875489.1  nuclear receptor-interacting protein 2 isoform X3

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