Format

Send to:

Choose Destination

CKA1 casein kinase alpha 1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 836873, updated on 10-Oct-2019

Summary

Gene symbol
CKA1
Gene description
casein kinase alpha 1
Primary source
Araport:AT5G67380
Locus tag
AT5G67380
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATCKA1; ATPK12D; casein kinase alpha 1; K8K14.10; K8K14_10
Summary
Casein kinase II (CK2) catalytic subunit (alpha 1). One known substrate of CK2 is Phytochrome Interacting Factor 1 (PIF1). CK2-mediated phosphorylation enhances the light-induced degradation of PIF1 to promote photomorphogenesis.

Genomic context

See CKA1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
10
Sequence:
Chromosome: 5; NC_003076.8 (26880966..26884079, complement)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene DUF1230 family protein (DUF1230) Neighboring gene Phototropic-responsive NPH3 family protein Neighboring gene glycosyltransferase-like protein Neighboring gene ncRNA Neighboring gene ncRNA

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

NM_001037088.2
NM_126138.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein serine/threonine kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
DNA repair IDA
Inferred from Direct Assay
more info
PubMed 
chromatin organization IDA
Inferred from Direct Assay
more info
PubMed 
chromatin organization IEP
Inferred from Expression Pattern
more info
PubMed 
circadian rhythm IGI
Inferred from Genetic Interaction
more info
PubMed 
regulation of cell cycle IEP
Inferred from Expression Pattern
more info
PubMed 
regulation of circadian rhythm IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of response to DNA damage stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
response to UV-C IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to gamma radiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
nucleolus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus ISM
Inferred from Sequence Model
more info
 
protein kinase CK2 complex IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
casein kinase alpha 1
NP_001032165.1
  • casein kinase alpha 1 (CKA1); FUNCTIONS IN: kinase activity; INVOLVED IN: protein amino acid phosphorylation; LOCATED IN: endomembrane system; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: casein kinase II, alpha chain 2 (TAIR:AT3G50000.1); Has 73369 Blast hits to 72658 proteins in 2362 species: Archae - 60; Bacteria - 7223; Metazoa - 28693; Fungi - 10783; Plants - 10981; Viruses - 246; Other Eukaryotes - 15383 (source: NCBI BLink).
NP_201539.2
  • casein kinase alpha 1 (CKA1); FUNCTIONS IN: kinase activity; INVOLVED IN: protein amino acid phosphorylation; LOCATED IN: endomembrane system; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase-like domain (InterPro:IPR011009); BEST Arabidopsis thaliana protein match is: casein kinase II, alpha chain 2 (TAIR:AT3G50000.1); Has 85531 Blast hits to 84684 proteins in 2530 species: Archae - 70; Bacteria - 9546; Metazoa - 32860; Fungi - 11294; Plants - 14699; Viruses - 299; Other Eukaryotes - 16763 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    26880966..26884079 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_126138.4NP_201539.2  casein kinase alpha 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_201539.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q08467
    Conserved Domains (2) summary
    cd14132
    Location:91395
    STKc_CK2_alpha; Catalytic subunit (alpha) of the Serine/Threonine Kinase, Casein Kinase 2
    pfam00069
    Location:110395
    Pkinase; Protein kinase domain
  2. NM_001037088.2NP_001032165.1  casein kinase alpha 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001032165.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q08467
    Conserved Domains (2) summary
    cd14132
    Location:91362
    STKc_CK2_alpha; Catalytic subunit (alpha) of the Serine/Threonine Kinase, Casein Kinase 2
    cl21464
    Location:33137
    cupin_like; Conserved domain found in cupin and related proteins
Support Center