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SDH1-1 succinate dehydrogenase 1-1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 836809, updated on 12-Aug-2026
Official Symbol
SDH1-1
Official Full Name
succinate dehydrogenase 1-1
Primary source
TAIR:AT5G66760
Locus tag
AT5G66760
See related
Araport:AT5G66760
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
MSN2.16; MSN2_16; succinate dehydrogenase 1-1
Summary
One of two genes in Arabidopsis that encode a flavoprotein subunit of the mitochondrial succinate dehydrogenase complex.
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See SDH1-1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
15
Sequence:
Chromosome: 5; NC_003076.8 (26653607..26657696)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene chromatin remodeling 1 Neighboring gene tRNA-Glu Neighboring gene ncRNA Neighboring gene GRAS family transcription factor

Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Salicylic Acid-Dependent Plant Stress Signaling via Mitochondrial Succinate Dehydrogenase. Belt K, et al. Plant Physiol, 2017 Apr. PMID 28209841, Free PMC Article
  2. A deficiency in the flavoprotein of Arabidopsis mitochondrial complex II results in elevated photosynthesis and better growth in nitrogen-limiting conditions. Fuentes D, et al. Plant Physiol, 2011 Nov. PMID 21921116, Free PMC Article
  3. The four subunits of mitochondrial respiratory complex II are encoded by multiple nuclear genes and targeted to mitochondria in Arabidopsis thaliana. Figueroa P, et al. Plant Mol Biol, 2002 Nov. PMID 12374303
  4. Mitochondrial cytochrome c oxidase and succinate dehydrogenase complexes contain plant specific subunits. Millar AH, et al. Plant Mol Biol, 2004 Sep. PMID 15604729
  5. Functional and composition differences between mitochondrial complex II in Arabidopsis and rice are correlated with the complex genetic history of the enzyme. Huang S, et al. Plant Mol Biol, 2010 Feb. PMID 19924544

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Data sugggest that salicylic acid (SA) acts at or near the ubiquinone binding site of mitochondrial succinate dehydrogenase (SDH) to stimulate activity and contributes to plant stress signaling by increased rates of mitochondrial H2O2 production.
    Title: Salicylic Acid-Dependent Plant Stress Signaling via Mitochondrial Succinate Dehydrogenase.
  2. SDH1-1/sdh1-1 seedlings grew considerably better in nitrogen-limiting conditions.
    Title: A deficiency in the flavoprotein of Arabidopsis mitochondrial complex II results in elevated photosynthesis and better growth in nitrogen-limiting conditions.
Submit: New GeneRIF Correction
Products Interactant Other Gene Complex Source Pubs Description

Homology

NM_126074.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ATP binding HDA PubMed 
enables cobalt ion binding HDA PubMed 
enables flavin adenine dinucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on the CH-CH group of donors IEA
Inferred from Electronic Annotation
more info
  
contributes_to succinate dehydrogenase (quinone) activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables succinate dehydrogenase (quinone) activity IEA
Inferred from Electronic Annotation
more info
  
contributes_to succinate dehydrogenase (quinone) activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables succinate dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
  
contributes_to succinate dehydrogenase activity TAS
Traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in electron transport chain IEA
Inferred from Electronic Annotation
more info
  
involved_in mitochondrial electron transport, succinate to ubiquinone IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within mitochondrial electron transport, succinate to ubiquinone TAS
Traceable Author Statement
more info
 PubMed 
involved_in tricarboxylic acid cycle IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
NOT located_in Golgi apparatus RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrion ISM
Inferred from Sequence Model
more info
  
located_in plant-type cell wall HDA PubMed 
located_in plastid HDA PubMed 
part_of respiratory chain complex II (succinate dehydrogenase) IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of respiratory chain complex II (succinate dehydrogenase) IDA
Inferred from Direct Assay
more info
 PubMed 
part_of respiratory chain complex II (succinate dehydrogenase) IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
succinate dehydrogenase 1-1
NP_201477.1
  • succinate dehydrogenase 1-1 (SDH1-1); FUNCTIONS IN: cobalt ion binding, succinate dehydrogenase activity, ATP binding; INVOLVED IN: mitochondrial electron transport, succinate to ubiquinone; LOCATED IN: mitochondrial respiratory chain complex II, mitochondrion, cell wall; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Succinate dehydrogenase, flavoprotein subunit (InterPro:IPR011281), Fumarate reductase/succinate dehydrogenase, FAD-binding site (InterPro:IPR003952), Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal (InterPro:IPR015939), Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal (InterPro:IPR003953), Succinate dehydrogenase/fumarate reductase, flavoprotein subunit (InterPro:IPR014006), Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal (InterPro:IPR004112); BEST Arabidopsis thaliana protein match is: succinate dehydrogenase 1-2 (TAIR:AT2G18450.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    26653607..26657696
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_126074.3 → NP_201477.1  succinate dehydrogenase 1-1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_201477.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O82663
    Conserved Domains (1) summary
    PLN00128
    Location:1 → 634
    PLN00128; Succinate dehydrogenase [ubiquinone] flavoprotein subunit
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O82663.1

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