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PARP9 poly(ADP-ribose) polymerase family member 9 [ Homo sapiens (human) ]

Gene ID: 83666, updated on 23-Nov-2017
Official Symbol
PARP9provided by HGNC
Official Full Name
poly(ADP-ribose) polymerase family member 9provided by HGNC
Primary source
HGNC:HGNC:24118
See related
Ensembl:ENSG00000138496 MIM:612065; Vega:OTTHUMG00000159522
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
BAL; BAL1; ARTD9; MGC:7868
Expression
Ubiquitous expression in spleen (RPKM 10.3), appendix (RPKM 10.1) and 25 other tissues See more
Orthologs
Location:
3q21.1
Exon count:
14
Annotation release Status Assembly Chr Location
108 current GRCh38.p7 (GCF_000001405.33) 3 NC_000003.12 (122527910..122564676, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (122246757..122283523, complement)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102723582 Neighboring gene karyopherin subunit alpha 1 Neighboring gene uncharacterized LOC107984000 Neighboring gene uncharacterized LOC105374071 Neighboring gene deltex E3 ubiquitin ligase 3L Neighboring gene poly(ADP-ribose) polymerase family member 14 pseudogene Neighboring gene poly(ADP-ribose) polymerase family member 15 Neighboring gene eukaryotic translation initiation factor 4B pseudogene 8

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Replication interactions

Interaction Pubs
Knockdown of poly (ADP-ribose) polymerase family, member 9 (PARP9) by siRNA inhibits the early stages of HIV-1 replication in 293T cells infected with VSV-G pseudotyped HIV-1 PubMed

Protein interactions

Protein Gene Interaction Pubs
Tat tat HIV-1 Tat upregulates the expression of poly (ADP-ribose) polymerase family, member 9 (PARP9) in human primary T cells PubMed

Go to the HIV-1, Human Interaction Database

  • Metabolism, organism-specific biosystem (from REACTOME)
    Metabolism, organism-specific biosystemMetabolic processes in human cells generate energy through the oxidation of molecules consumed in the diet and mediate the synthesis of diverse essential molecules not taken in the diet as well as th...
  • Metabolism of vitamins and cofactors, organism-specific biosystem (from REACTOME)
    Metabolism of vitamins and cofactors, organism-specific biosystemVitamins are a diverse group of organic compounds, classified according to their solubility, either fat-soluble or water-soluble, that are either not synthesized or synthesized only in limited amount...
  • Metabolism of water-soluble vitamins and cofactors, organism-specific biosystem (from REACTOME)
    Metabolism of water-soluble vitamins and cofactors, organism-specific biosystemVitamins are a diverse group of organic compounds, required in small amounts in the diet. They have distinct biochemical roles, often as coenzymes, and are either not synthesized or synthesized only ...
  • Nicotinamide salvaging, organism-specific biosystem (from REACTOME)
    Nicotinamide salvaging, organism-specific biosystemNicotinamide (NAM) levels are modulated by the action of three enzymes involved in nicotinamide salvaging. They are nicotinamide deaminase, nicotinamide phosphoribosyltransferase and nicotinate phosp...
  • Nicotinate metabolism, organism-specific biosystem (from REACTOME)
    Nicotinate metabolism, organism-specific biosystemNicotinate (niacin) and nicotinamide are precursors of the coenzymes nicotinamide-adenine dinucleotide (NAD+) and nicotinamide-adenine dinucleotide phosphate (NADP+). When NAD+ and NADP+ are intercha...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • FLJ26637, FLJ35310, FLJ41418, FLJ43593, DKFZp666B0810, DKFZp686M15238

Gene Ontology Provided by GOA

Function Evidence Code Pubs
ADP-D-ribose binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
NAD+ ADP-ribosyltransferase activity IDA
Inferred from Direct Assay
more info
PubMed 
NOT NAD+ ADP-ribosyltransferase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
NAD+ ADP-ribosyltransferase activity TAS
Traceable Author Statement
more info
 
NOT NAD+ binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
STAT family protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enzyme binding IPI
Inferred from Physical Interaction
more info
PubMed 
enzyme inhibitor activity IDA
Inferred from Direct Assay
more info
PubMed 
histone binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
transcriptional repressor activity, RNA polymerase II transcription factor binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
ubiquitin-like protein ligase binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
NAD biosynthesis via nicotinamide riboside salvage pathway TAS
Traceable Author Statement
more info
 
cell migration TAS
Traceable Author Statement
more info
PubMed 
defense response to virus IEA
Inferred from Electronic Annotation
more info
 
double-strand break repair IMP
Inferred from Mutant Phenotype
more info
PubMed 
innate immune response IEA
Inferred from Electronic Annotation
more info
 
negative regulation of catalytic activity IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of gene expression IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of transcription from RNA polymerase II promoter IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of chromatin binding IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of defense response to virus by host IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of double-strand break repair via nonhomologous end joining IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of interferon-gamma-mediated signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of protein localization to nucleus IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of transcription, DNA-templated IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of tyrosine phosphorylation of STAT protein IMP
Inferred from Mutant Phenotype
more info
PubMed 
posttranscriptional regulation of gene expression IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein ADP-ribosylation IDA
Inferred from Direct Assay
more info
PubMed 
NOT protein poly-ADP-ribosylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of response to interferon-gamma IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytosol IDA
Inferred from Direct Assay
more info
 
cytosol TAS
Traceable Author Statement
more info
 
membrane IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion IDA
Inferred from Direct Assay
more info
 
nucleoplasm IDA
Inferred from Direct Assay
more info
 
nucleus IC
Inferred by Curator
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
colocalizes_with nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus TAS
Traceable Author Statement
more info
PubMed 
protein complex IDA
Inferred from Direct Assay
more info
PubMed 
site of DNA damage IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
poly [ADP-ribose] polymerase 9
Names
ADP-ribosyltransferase diphtheria toxin-like 9
PARP-9
b aggressive lymphoma protein
poly (ADP-ribose) polymerase 9
NP_001139574.1
NP_001139575.1
NP_001139576.1
NP_001139577.1
NP_001139578.1
NP_113646.2
XP_005247877.1
XP_011511520.1
XP_016862793.1
XP_016862794.1
XP_016862795.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001146102.1NP_001139574.1  poly [ADP-ribose] polymerase 9 isoform a

    See identical proteins and their annotated locations for NP_001139574.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same isoform (a).
    Source sequence(s)
    AK313494, BC039580, BU675792, DC368112
    Consensus CDS
    CCDS3014.1
    UniProtKB/Swiss-Prot
    Q8IXQ6
    Conserved Domains (4) summary
    COG2110
    Location:317483
    YmdB; O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain [Translation, ribosomal structure and biogenesis]
    cd01439
    Location:702821
    TCCD_inducible_PARP_like; Poly(ADP-ribose) polymerases catalyse the covalent attachment of ADP-ribose units from NAD+ to itself and to a limited number of other DNA binding proteins, which decreases their affinity for DNA. Poly(ADP-ribose) polymerase is a regulatory component ...
    cd02903
    Location:317453
    Macro_BAL_like; Macro domain, BAL_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). ...
    cd02907
    Location:117295
    Macro_Af1521_BAL_like; Macro domain, Af1521- and BAL-like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose ...
  2. NM_001146103.1NP_001139575.1  poly [ADP-ribose] polymerase 9 isoform b

    See identical proteins and their annotated locations for NP_001139575.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. This results in a shorter protein (isoform b), compared to isoform a. Variants 3, 4 and 5 encode the same isoform (b).
    Source sequence(s)
    AF307339, AL713679, BU675792, DB096326
    Consensus CDS
    CCDS54634.1
    UniProtKB/Swiss-Prot
    Q8IXQ6
    Related
    ENSP00000419506.1, OTTHUMP00000215679, ENST00000477522.6, OTTHUMT00000355958
    Conserved Domains (4) summary
    COG2110
    Location:282448
    YmdB; O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain [Translation, ribosomal structure and biogenesis]
    cd01439
    Location:667786
    TCCD_inducible_PARP_like; Poly(ADP-ribose) polymerases catalyse the covalent attachment of ADP-ribose units from NAD+ to itself and to a limited number of other DNA binding proteins, which decreases their affinity for DNA. Poly(ADP-ribose) polymerase is a regulatory component ...
    cd02903
    Location:282418
    Macro_BAL_like; Macro domain, BAL_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). ...
    cd02907
    Location:82260
    Macro_Af1521_BAL_like; Macro domain, Af1521- and BAL-like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose ...
  3. NM_001146104.1NP_001139576.1  poly [ADP-ribose] polymerase 9 isoform b

    See identical proteins and their annotated locations for NP_001139576.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR and uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. This results in a shorter protein (isoform b), compared to isoform a. Variants 3, 4 and 5 encode the same isoform (b).
    Source sequence(s)
    BC039580, BU675792, DC309545
    Consensus CDS
    CCDS54634.1
    UniProtKB/Swiss-Prot
    Q8IXQ6
    Related
    ENSP00000419001.1, OTTHUMP00000215682, ENST00000471785.5, OTTHUMT00000355961
    Conserved Domains (4) summary
    COG2110
    Location:282448
    YmdB; O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain [Translation, ribosomal structure and biogenesis]
    cd01439
    Location:667786
    TCCD_inducible_PARP_like; Poly(ADP-ribose) polymerases catalyse the covalent attachment of ADP-ribose units from NAD+ to itself and to a limited number of other DNA binding proteins, which decreases their affinity for DNA. Poly(ADP-ribose) polymerase is a regulatory component ...
    cd02903
    Location:282418
    Macro_BAL_like; Macro domain, BAL_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). ...
    cd02907
    Location:82260
    Macro_Af1521_BAL_like; Macro domain, Af1521- and BAL-like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose ...
  4. NM_001146105.1NP_001139577.1  poly [ADP-ribose] polymerase 9 isoform b

    See identical proteins and their annotated locations for NP_001139577.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR and uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. This results in a shorter protein (isoform b), compared to isoform a. Variants 3, 4 and 5 encode the same isoform (b).
    Source sequence(s)
    BC039580, BU675792, DC368112
    Consensus CDS
    CCDS54634.1
    UniProtKB/Swiss-Prot
    Q8IXQ6
    Conserved Domains (4) summary
    COG2110
    Location:282448
    YmdB; O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain [Translation, ribosomal structure and biogenesis]
    cd01439
    Location:667786
    TCCD_inducible_PARP_like; Poly(ADP-ribose) polymerases catalyse the covalent attachment of ADP-ribose units from NAD+ to itself and to a limited number of other DNA binding proteins, which decreases their affinity for DNA. Poly(ADP-ribose) polymerase is a regulatory component ...
    cd02903
    Location:282418
    Macro_BAL_like; Macro domain, BAL_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). ...
    cd02907
    Location:82260
    Macro_Af1521_BAL_like; Macro domain, Af1521- and BAL-like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose ...
  5. NM_001146106.1NP_001139578.1  poly [ADP-ribose] polymerase 9 isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR, 3' UTR and 3' coding region, compared to variant 1, which results in a frameshift. The encoded protein (isoform c) has a shorter and distinct C-terminus, compared to isoform a.
    Source sequence(s)
    AB209742, AK092629, BC017463, BP259272, DC309545
    Consensus CDS
    CCDS54633.1
    UniProtKB/TrEMBL
    Q59ER9
    Related
    ENSP00000418894.1, OTTHUMP00000215680, ENST00000462315.5, OTTHUMT00000355959
    Conserved Domains (4) summary
    COG2110
    Location:282448
    YmdB; O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain [Translation, ribosomal structure and biogenesis]
    cd02903
    Location:282418
    Macro_BAL_like; Macro domain, BAL_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). ...
    cd02907
    Location:82260
    Macro_Af1521_BAL_like; Macro domain, Af1521- and BAL-like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose ...
    cl00283
    Location:667695
    ADP_ribosyl; ADP_ribosylating enzymes catalyze the transfer of ADP_ribose from NAD+ to substrates. Bacterial toxins are cytoplasmic and catalyze the transfer of a single ADP_ribose unit to eukaryotic elongation factor 2, halting protein synthesis and killing the cell. ...
  6. NM_031458.2NP_113646.2  poly [ADP-ribose] polymerase 9 isoform a

    See identical proteins and their annotated locations for NP_113646.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (a). Both variants 1 and 2 encode the same isoform (a).
    Source sequence(s)
    AF307338, AL713679, BU675792, DB096326
    Consensus CDS
    CCDS3014.1
    UniProtKB/Swiss-Prot
    Q8IXQ6
    Related
    ENSP00000353512.2, OTTHUMP00000215678, ENST00000360356.6, OTTHUMT00000355957
    Conserved Domains (4) summary
    COG2110
    Location:317483
    YmdB; O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain [Translation, ribosomal structure and biogenesis]
    cd01439
    Location:702821
    TCCD_inducible_PARP_like; Poly(ADP-ribose) polymerases catalyse the covalent attachment of ADP-ribose units from NAD+ to itself and to a limited number of other DNA binding proteins, which decreases their affinity for DNA. Poly(ADP-ribose) polymerase is a regulatory component ...
    cd02903
    Location:317453
    Macro_BAL_like; Macro domain, BAL_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). ...
    cd02907
    Location:117295
    Macro_Af1521_BAL_like; Macro domain, Af1521- and BAL-like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose ...

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 108

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p7 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p7 Primary Assembly

    Range
    122527910..122564676 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017007305.1XP_016862794.1  poly [ADP-ribose] polymerase 9 isoform X2

    UniProtKB/Swiss-Prot
    Q8IXQ6
    Conserved Domains (4) summary
    COG2110
    Location:282448
    YmdB; O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain [Translation, ribosomal structure and biogenesis]
    cd01439
    Location:667786
    TCCD_inducible_PARP_like; Poly(ADP-ribose) polymerases catalyse the covalent attachment of ADP-ribose units from NAD+ to itself and to a limited number of other DNA binding proteins, which decreases their affinity for DNA. Poly(ADP-ribose) polymerase is a regulatory component ...
    cd02903
    Location:282418
    Macro_BAL_like; Macro domain, BAL_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). ...
    cd02907
    Location:82260
    Macro_Af1521_BAL_like; Macro domain, Af1521- and BAL-like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose ...
  2. XM_017007304.1XP_016862793.1  poly [ADP-ribose] polymerase 9 isoform X1

    UniProtKB/Swiss-Prot
    Q8IXQ6
    Conserved Domains (4) summary
    COG2110
    Location:317483
    YmdB; O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain [Translation, ribosomal structure and biogenesis]
    cd01439
    Location:702821
    TCCD_inducible_PARP_like; Poly(ADP-ribose) polymerases catalyse the covalent attachment of ADP-ribose units from NAD+ to itself and to a limited number of other DNA binding proteins, which decreases their affinity for DNA. Poly(ADP-ribose) polymerase is a regulatory component ...
    cd02903
    Location:317453
    Macro_BAL_like; Macro domain, BAL_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). ...
    cd02907
    Location:117295
    Macro_Af1521_BAL_like; Macro domain, Af1521- and BAL-like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose ...
  3. XM_005247820.2XP_005247877.1  poly [ADP-ribose] polymerase 9 isoform X1

    See identical proteins and their annotated locations for XP_005247877.1

    UniProtKB/Swiss-Prot
    Q8IXQ6
    Conserved Domains (4) summary
    COG2110
    Location:317483
    YmdB; O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain [Translation, ribosomal structure and biogenesis]
    cd01439
    Location:702821
    TCCD_inducible_PARP_like; Poly(ADP-ribose) polymerases catalyse the covalent attachment of ADP-ribose units from NAD+ to itself and to a limited number of other DNA binding proteins, which decreases their affinity for DNA. Poly(ADP-ribose) polymerase is a regulatory component ...
    cd02903
    Location:317453
    Macro_BAL_like; Macro domain, BAL_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). ...
    cd02907
    Location:117295
    Macro_Af1521_BAL_like; Macro domain, Af1521- and BAL-like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose ...
  4. XM_017007306.1XP_016862795.1  poly [ADP-ribose] polymerase 9 isoform X2

    UniProtKB/Swiss-Prot
    Q8IXQ6
    Conserved Domains (4) summary
    COG2110
    Location:282448
    YmdB; O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain [Translation, ribosomal structure and biogenesis]
    cd01439
    Location:667786
    TCCD_inducible_PARP_like; Poly(ADP-ribose) polymerases catalyse the covalent attachment of ADP-ribose units from NAD+ to itself and to a limited number of other DNA binding proteins, which decreases their affinity for DNA. Poly(ADP-ribose) polymerase is a regulatory component ...
    cd02903
    Location:282418
    Macro_BAL_like; Macro domain, BAL_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). ...
    cd02907
    Location:82260
    Macro_Af1521_BAL_like; Macro domain, Af1521- and BAL-like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose ...
  5. XM_011513218.1XP_011511520.1  poly [ADP-ribose] polymerase 9 isoform X3

    Conserved Domains (4) summary
    COG2110
    Location:317483
    YmdB; O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain [Translation, ribosomal structure and biogenesis]
    cd02903
    Location:317453
    Macro_BAL_like; Macro domain, BAL_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). ...
    cd02907
    Location:117295
    Macro_Af1521_BAL_like; Macro domain, Af1521- and BAL-like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose ...
    cl00283
    Location:702729
    ADP_ribosyl; ADP_ribosylating enzymes catalyze the transfer of ADP_ribose from NAD+ to substrates. Bacterial toxins are cytoplasmic and catalyze the transfer of a single ADP_ribose unit to eukaryotic elongation factor 2, halting protein synthesis and killing the cell. ...

RNA

  1. XR_001740306.1 RNA Sequence

  2. XR_001740305.1 RNA Sequence

  3. XR_001740308.1 RNA Sequence

  4. XR_001740309.1 RNA Sequence

  5. XR_001740307.1 RNA Sequence

Alternate CHM1_1.1

Genomic

  1. NC_018914.2 Alternate CHM1_1.1

    Range
    122210449..122247205 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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