PEX14 peroxin 14 [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: PEX14
Official Full Name: peroxin 14
Primary source: TAIR:AT5G62810
Locus tag: AT5G62810
See related: Araport:AT5G62810
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ATPEX14; MQB2.13; MQB2_13; PED2; peroxin 14; PEROXISOME DEFECTIVE 2
Summary: mutant has a defect in the intracellular transport of thiolase from the cytosol to glyoxysomes (formerly known as ped2)
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Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

PEX5 binding to the PEX14N-terminal domain (PEX14N) has no effect on the affinity of PEX5 for a PTS1 containing peptides.
Title: PEX14 binding to Arabidopsis PEX5 has differential effects on PTS1 and PTS2 cargo occupancy of the receptor.
PEX14 facilitates peroxisomal matrix protein import in plants.
Title: Matrix proteins are inefficiently imported into Arabidopsis peroxisomes lacking the receptor-docking peroxin PEX14.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

NM_125676.5

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within peroxisome organization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in protein import into peroxisome matrix, docking	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein targeting to peroxisome	TAS Traceable Author Statement more info	PubMed

Component	Evidence Code	Pubs
located_in cytosol	IDA Inferred from Direct Assay more info	PubMed
located_in mitochondrion	HDA more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info
located_in peroxisome	HDA more info	PubMed
located_in peroxisome	IDA Inferred from Direct Assay more info	PubMed
located_in plastid	HDA more info	PubMed

NP_201087.3

peroxin 14 (PEX14); FUNCTIONS IN: protein transporter activity, protein binding; INVOLVED IN: peroxisome organization, protein targeting to peroxisome; LOCATED IN: cytosol, peroxisome, plasma membrane; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Peroxisome membrane anchor protein Pex14p, N-terminal (InterPro:IPR006785); BEST Arabidopsis thaliana protein match is: Protein with RING/U-box and TRAF-like domains (TAIR:AT5G62800.1); Has 366 Blast hits to 354 proteins in 137 species: Archae - 0; Bacteria - 2; Metazoa - 94; Fungi - 149; Plants - 89; Viruses - 0; Other Eukaryotes - 32 (source: NCBI BLink).