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Ugcg UDP-glucose ceramide glucosyltransferase [ Rattus norvegicus (Norway rat) ]

Gene ID: 83626, updated on 23-May-2018
Official Symbol
Ugcgprovided by RGD
Official Full Name
UDP-glucose ceramide glucosyltransferaseprovided by RGD
Primary source
RGD:621870
See related
Ensembl:ENSRNOG00000015644
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to ceramide to form glucosylceramide [RGD, Feb 2006]
Expression
Biased expression in Adrenal (RPKM 107.6), Spleen (RPKM 95.4) and 9 other tissues See more
Orthologs
See Ugcg in Genome Data Viewer
Location:
5q24
Exon count:
10
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (76376722..76419564)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 5 NC_005104.3 (80530140..80562612)

Chromosome 5 - NC_005104.4Genomic Context describing neighboring genes Neighboring gene hypothetical protein LOC686050 Neighboring gene uncharacterized LOC102550849 Neighboring gene uncharacterized LOC103692364 Neighboring gene uncharacterized LOC102551074 Neighboring gene sushi domain containing 1

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
ceramide glucosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ceramide glucosyltransferase activity IDA
Inferred from Direct Assay
more info
PubMed 
dihydroceramide glucosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
glucosylceramide biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
Golgi membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Preferred Names
ceramide glucosyltransferase
Names
GCS
GLCT-1
UDP-glucose:N-acylsphingosine D-glucosyltransferase
UDP-glucose:ceramide glycosyltransferase
glucosylceramide synthase
NP_113983.1
XP_017449147.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_031795.2NP_113983.1  ceramide glucosyltransferase

    See identical proteins and their annotated locations for NP_113983.1

    Status: VALIDATED

    Source sequence(s)
    AABR07048392
    UniProtKB/Swiss-Prot
    Q9R0E0
    Related
    ENSRNOP00000021110.3, ENSRNOT00000021110.4
    Conserved Domains (2) summary
    cd02520
    Location:51280
    Glucosylceramide_synthase; Glucosylceramide synthase catalyzes the first glycosylation step of glycosphingolipid synthesis
    pfam13641
    Location:51276
    Glyco_tranf_2_3; Glycosyltransferase like family 2

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005104.4 Reference Rnor_6.0 Primary Assembly

    Range
    76376722..76419564
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017593658.1XP_017449147.1  ceramide glucosyltransferase isoform X1

Alternate Rn_Celera

Genomic

  1. AC_000073.1 Alternate Rn_Celera

    Range
    72854114..72886901
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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