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THAP2 THAP domain containing 2 [ Homo sapiens (human) ]

Gene ID: 83591, updated on 23-Nov-2021

Summary

Official Symbol
THAP2provided by HGNC
Official Full Name
THAP domain containing 2provided by HGNC
Primary source
HGNC:HGNC:20854
See related
Ensembl:ENSG00000173451 MIM:612531
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in adrenal (RPKM 3.6), ovary (RPKM 2.6) and 24 other tissues See more
Orthologs
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Genomic context

See THAP2 in Genome Data Viewer
Location:
12q21.1
Exon count:
3
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 12 NC_000012.12 (71664301..71680644)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (72058081..72074424)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene leucine rich repeat containing G protein-coupled receptor 5 Neighboring gene uncharacterized LOC105369833 Neighboring gene zinc finger C3H1-type containing Neighboring gene uncharacterized LOC107984529 Neighboring gene uncharacterized LOC107984530 Neighboring gene transmembrane protein 19

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

Associated conditions

Description Tests
The genetic architecture of economic and political preferences.
GeneReviews: Not available

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Potential readthrough

Included gene: TMEM19

Homology

Clone Names

  • DKFZp564I0422

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in nucleolus IDA
Inferred from Direct Assay
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
THAP domain-containing protein 2
Names
THAP domain containing, apoptosis associated protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_031435.4NP_113623.1  THAP domain-containing protein 2

    See identical proteins and their annotated locations for NP_113623.1

    Status: VALIDATED

    Source sequence(s)
    AC073612, AL136607, DB301707
    Consensus CDS
    CCDS9001.1
    UniProtKB/Swiss-Prot
    Q9H0W7
    Related
    ENSP00000310796.2, ENST00000308086.3
    Conserved Domains (1) summary
    pfam05485
    Location:580
    THAP; THAP domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p13 Primary Assembly

    Range
    71664301..71680644
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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