U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Tex16 testis expressed gene 16 [ Mus musculus (house mouse) ]

Gene ID: 83556, updated on 3-Mar-2023

Summary

Go to the top of the page Help
Official Symbol
Tex16provided by MGI
Official Full Name
testis expressed gene 16provided by MGI
Primary source
MGI:MGI:1890545
See related
Ensembl:ENSMUSG00000034555 Ensembl:ENSMUSG00000079460 AllianceGenome:MGI:1890545
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4933403O08Rik
Summary
Predicted to enable U6 snRNA binding activity and pre-mRNA binding activity. Predicted to be part of Prp19 complex; U2-type catalytic step 1 spliceosome; and U2-type catalytic step 2 spliceosome. Orthologous to human TEX16P (testis expressed 16, pseudogene). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Tex16 in Genome Data Viewer
Location:
X; X E1
Exon count:
25
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) X NC_000086.8 (110806455..111037023)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (111896766..112127326)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene predicted gene, 52469 Neighboring gene guanosine diphosphate (GDP) dissociation inhibitor 2 pseudogene Neighboring gene transmembrane 9 superfamily member 3 pseudogene Neighboring gene DnaJ (Hsp40) homolog, subfamily A, member 1 pseudogene Neighboring gene barrier to autointegration factor 1 pseudogene Neighboring gene apolipoprotein O-like

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Differential expression of sex-linked and autosomal germ-cell-specific genes during spermatogenesis in the mouse. Wang PJ, et al. Hum Mol Genet, 2005 Oct 1. PMID 16118233, Free PMC Article
  2. Genomewide discovery and classification of candidate ovarian fertility genes in the mouse. Gallardo TD, et al. Genetics, 2007 Sep. PMID 17660561, Free PMC Article
  3. An abundance of X-linked genes expressed in spermatogonia. Wang PJ, et al. Nat Genet, 2001 Apr. PMID 11279525
  4. Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis. Wang X, et al. Cell, 2006 Nov 17. PMID 17110338
  5. A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome. Mural RJ, et al. Science, 2002 May 31. PMID 12040188

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Tex16 is a gene that is expressed in testis that was identified in a genome-wide cDNA subtraction screen.
    Title: An abundance of X-linked genes expressed in spermatogonia.
  2. Germ-cell-specific sex-linked genes, like Tex16, are subject to meiotic sex-chromosome inactivation (MSCI) during spermatogenesis.
    Title: Differential expression of sex-linked and autosomal germ-cell-specific genes during spermatogenesis in the mouse.
  3. Transcripts highly enriched in ovary; gene identified as candidate female fertility factor.
    Title: Genomewide discovery and classification of candidate ovarian fertility genes in the mouse.
Submit: New GeneRIF Correction

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables U6 snRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
enables pre-mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
Component Evidence Code Pubs
part_of Prp19 complex IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
part_of U2-type catalytic step 1 spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
part_of U2-type catalytic step 2 spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
testis expressed gene 16

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001177389.1 → NP_001170860.1  testis expressed gene 16 isoform 3

    See identical proteins and their annotated locations for NP_001170860.1

    Status: PROVISIONAL

    Source sequence(s)
    AC021631, AL672309
    Consensus CDS
    CCDS57772.1
    UniProtKB/TrEMBL
    F6RC93, F6UK53
    Related
    ENSMUSP00000121926.3, ENSMUST00000152343.8

  2. NM_001417261.1 → NP_001404190.1  testis expressed gene 16 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC021631, AL831779, BX005180

  3. NM_001417263.2 → NP_001404192.1  testis expressed gene 16 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC021631, AL672309, AL831779, BX005180

  4. NM_001417277.1 → NP_001404206.1  testis expressed gene 16 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC021631, AL672309, AL831779, BX005180

  5. NM_031382.3 → NP_113559.3  testis expressed gene 16 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC021631, AL831779, BX005180
    Consensus CDS
    CCDS30358.1
    Related
    ENSMUSP00000048187.7, ENSMUST00000038546.7

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    110806455..111037023
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

  2. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    111081135..111159047
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017318644.2 → XP_017174133.1  testis expressed gene 16 isoform X1

    Conserved Domains (3) summary
    pfam10534
    Location:120 → 180
    CRIC_ras_sig; Connector enhancer of kinase suppressor of ras
    NF000535
    Location:1071 → 1305
    MSCRAMM_SdrC; MSCRAMM family adhesin SdrC
    cl15755
    Location:17 → 79
    SAM_superfamily; SAM (Sterile alpha motif )
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools
Miscellaneous