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TAAR8 trace amine associated receptor 8 [ Homo sapiens (human) ]

Gene ID: 83551, updated on 13-May-2022

Summary

Official Symbol
TAAR8provided by HGNC
Official Full Name
trace amine associated receptor 8provided by HGNC
Primary source
HGNC:HGNC:14964
See related
Ensembl:ENSG00000146385 MIM:606927; AllianceGenome:HGNC:14964
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TA5; TAR5; TRAR5; TaR-5; TaR-8; GPR102
Summary
This gene is part of the trace amine receptor cluster on chromosome 6 and encodes an orphan G-protein coupled receptor. Upregulated expression of this gene in astroglial cells upon exposure to lipopolysaccharides suggests a function for the encoded protein in the brain. [provided by RefSeq, Jul 2016]
Orthologs
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Genomic context

See TAAR8 in Genome Data Viewer
Location:
6q23.2
Exon count:
1
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (132552672..132553756)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (133747638..133748722)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (132873811..132874895)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene ribosomal protein L21 pseudogene 66 Neighboring gene trace amine associated receptor 9 Neighboring gene trace amine associated receptor 7, pseudogene Neighboring gene trace amine associated receptor 6

Genomic regions, transcripts, and products

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity TAS
Traceable Author Statement
more info
PubMed 
enables trace-amine receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
trace amine-associated receptor 8
Names
G-protein coupled receptor 102
trace amine receptor 5
trace amine receptor 8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_053278.3NP_444508.1  trace amine-associated receptor 8

    See identical proteins and their annotated locations for NP_444508.1

    Status: VALIDATED

    Source sequence(s)
    AL513524
    Consensus CDS
    CCDS5154.1
    UniProtKB/Swiss-Prot
    Q969N4
    Related
    ENSP00000275200.1, ENST00000275200.1
    Conserved Domains (1) summary
    pfam00001
    Location:48310
    7tm_1; 7 transmembrane receptor (rhodopsin family)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

    Range
    132552672..132553756
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060930.1 Alternate T2T-CHM13v2.0

    Range
    133747638..133748722
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)