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TDT tonoplast dicarboxylate transporter [ Arabidopsis thaliana (thale cress) ]

Gene ID: 834806, updated on 11-Oct-2018

Summary

Gene symbol
TDT
Gene description
tonoplast dicarboxylate transporter
Primary source
Araport:AT5G47560
Locus tag
AT5G47560
Gene type
protein coding
RNA name
tonoplast dicarboxylate transporter
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATSDAT; ATTDT; tonoplast dicarboxylate transporter; TONOPLAST DICARBOXYLATE TRANSPORTER
Summary
Encodes a tonoplast malate/fumarate transporter.

Genomic context

See TDT in Genome Data Viewer
Location:
chromosome: 5
Exon count:
3
Sequence:
Chromosome: 5; NC_003076.8 (19287369..19291103, complement)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Auxin-responsive family protein Neighboring gene Mo25 family protein Neighboring gene Cystatin/monellin superfamily protein Neighboring gene NADH dehydrogenase ubiquinone 1 beta subcomplex subunit Neighboring gene transmembrane protein

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

NM_124129.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
malate transmembrane transporter activity IDA
Inferred from Direct Assay
more info
PubMed 
malate transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
sodium:dicarboxylate symporter activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
dicarboxylic acid transport ISS
Inferred from Sequence or Structural Similarity
more info
 
malate transport TAS
Traceable Author Statement
more info
PubMed 
regulation of intracellular pH TAS
Traceable Author Statement
more info
PubMed 
sodium ion transport IEA
Inferred from Electronic Annotation
more info
 
sodium ion transport ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
cell TAS
Traceable Author Statement
more info
PubMed 
integral component of membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
vacuolar membrane IEA
Inferred from Electronic Annotation
more info
 
vacuole IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
tonoplast dicarboxylate transporter
NP_199567.1
  • tonoplast dicarboxylate transporter (TDT); CONTAINS InterPro DOMAIN/s: Sodium/sulphate symporter (InterPro:IPR001898); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    19287369..19291103 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_124129.4NP_199567.1  tonoplast dicarboxylate transporter [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_199567.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8LG88
    Conserved Domains (2) summary
    COG0471
    Location:74529
    CitT; Di- and tricarboxylate transporter [Carbohydrate transport and metabolism]
    cd01115
    Location:76534
    SLC13_permease; Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is ...
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