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Chrdl1 chordin-like 1 [ Mus musculus (house mouse) ]

Gene ID: 83453, updated on 28-Aug-2018

Summary

Official Symbol
Chrdl1provided by MGI
Official Full Name
chordin-like 1provided by MGI
Primary source
MGI:MGI:1933172
See related
Ensembl:ENSMUSG00000031283 Vega:OTTMUSG00000018903
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
CHL; CHL1; VOPT; Nrln1
Expression
Broad expression in genital fat pad adult (RPKM 5.5), bladder adult (RPKM 4.9) and 18 other tissues See more
Orthologs

Genomic context

See Chrdl1 in Genome Data Viewer
Location:
X; X F2
Exon count:
12
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) X NC_000086.7 (143285674..143394265, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) X NC_000086.6 (139720217..139828805, complement)

Chromosome X - NC_000086.7Genomic Context describing neighboring genes Neighboring gene retrotransposon Gag like 9 Neighboring gene actin, beta pseudogene Neighboring gene p21 (RAC1) activated kinase 3 Neighboring gene calpain 6

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Process Evidence Code Pubs
cell differentiation IEA
Inferred from Electronic Annotation
more info
 
cell fate determination ISO
Inferred from Sequence Orthology
more info
 
compound eye development ISO
Inferred from Sequence Orthology
more info
 
eye development ISO
Inferred from Sequence Orthology
more info
 
multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
negative regulation of BMP signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
nervous system development IEA
Inferred from Electronic Annotation
more info
 
neuron differentiation ISO
Inferred from Sequence Orthology
more info
 
ossification IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
extracellular region IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
chordin-like protein 1
Names
neuralin-1
neurogenesin-1
ventroptin-alpha
ventroptin-beta

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001114385.1NP_001107857.1  chordin-like protein 1 isoform 1 precursor

    See identical proteins and their annotated locations for NP_001107857.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the shorter transcript and encodes the longer isoform (1).
    Source sequence(s)
    AF321853, AL713920, BX119959
    Consensus CDS
    CCDS53208.1
    UniProtKB/Swiss-Prot
    Q920C1
    Related
    ENSMUSP00000108499.2, ENSMUST00000112878.8
    Conserved Domains (1) summary
    cl17735
    Location:110173
    VWC; von Willebrand factor type C domain
  2. NM_001358592.1NP_001345521.1  chordin-like protein 1 isoform 3 precursor

    Status: VALIDATED

    Source sequence(s)
    AL713920, BX119959
    Conserved Domains (1) summary
    cl17735
    Location:111174
    VWC; von Willebrand factor type C domain
  3. NM_031258.3NP_112548.2  chordin-like protein 1 isoform 2 precursor

    See identical proteins and their annotated locations for NP_112548.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 3' UTR and lacks a portion of the 3' coding region, compared to variant 1. The encoded isoform (2) is shorter and has a distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AF296451, AL713920, BX119959
    Consensus CDS
    CCDS30453.1
    UniProtKB/Swiss-Prot
    Q920C1
    UniProtKB/TrEMBL
    Q3TP73
    Related
    ENSMUSP00000074230.5, OTTMUSP00000020440, ENSMUST00000074660.11, OTTMUST00000045447
    Conserved Domains (1) summary
    cl17735
    Location:110173
    VWC; von Willebrand factor type C domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000086.7 Reference GRCm38.p4 C57BL/6J

    Range
    143285674..143394265 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017318643.1XP_017174132.1  chordin-like protein 1 isoform X3

  2. XM_006529001.3XP_006529064.1  chordin-like protein 1 isoform X1

    Conserved Domains (1) summary
    cl17735
    Location:111174
    VWC; von Willebrand factor type C domain
  3. XM_006529002.3XP_006529065.1  chordin-like protein 1 isoform X2

    Conserved Domains (1) summary
    cl17735
    Location:110173
    VWC; von Willebrand factor type C domain
  4. XM_006529003.3XP_006529066.1  chordin-like protein 1 isoform X4

    Conserved Domains (1) summary
    cl17735
    Location:111174
    VWC; von Willebrand factor type C domain
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