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CCDC70 coiled-coil domain containing 70 [ Homo sapiens (human) ]

Gene ID: 83446, updated on 26-Oct-2022

Summary

Official Symbol
CCDC70provided by HGNC
Official Full Name
coiled-coil domain containing 70provided by HGNC
Primary source
HGNC:HGNC:25303
See related
Ensembl:ENSG00000123171 AllianceGenome:HGNC:25303
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis (RPKM 39.7) See more
Orthologs
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Genomic context

See CCDC70 in Genome Data Viewer
Location:
13q14.3
Exon count:
3
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 13 NC_000013.11 (51861969..51866232)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 13 NC_060937.1 (51076664..51080932)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 13 NC_000013.10 (52436105..52440368)

Chromosome 13 - NC_000013.11Genomic Context describing neighboring genes Neighboring gene WD repeat and FYVE domain containing 2 Neighboring gene uncharacterized LOC124903177 Neighboring gene dehydrogenase/reductase 12 Neighboring gene uncharacterized LOC107984561 Neighboring gene transmembrane protein 272 Neighboring gene CTAGE family member 3, pseudogene Neighboring gene ATPase copper transporting beta Neighboring gene fatty acid binding protein 5 pseudogene 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ25853, DKFZp434K1172

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
coiled-coil domain-containing protein 70

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001346075.2NP_001333004.2  coiled-coil domain-containing protein 70

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein.
    Source sequence(s)
    AL162377
    Consensus CDS
    CCDS9431.2
  2. NM_031290.4NP_112580.3  coiled-coil domain-containing protein 70

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein.
    Source sequence(s)
    AL162377
    Consensus CDS
    CCDS9431.2
    Related
    ENSP00000242819.5, ENST00000242819.7

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000013.11 Reference GRCh38.p14 Primary Assembly

    Range
    51861969..51866232
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060937.1 Alternate T2T-CHM13v2.0

    Range
    51076664..51080932
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)