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BIP2 Heat shock protein 70 (Hsp 70) family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 834207, updated on 9-Sep-2020

Summary

Gene symbol
BIP2
Gene description
Heat shock protein 70 (Hsp 70) family protein
Primary source
Araport:AT5G42020
Locus tag
AT5G42020
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
BIP; luminal binding protein; MJC20.12; MJC20_12
Summary
Luminal binding protein (BiP2) involved in polar nuclei fusion during proliferation of endosperm nuclei.

Genomic context

See BIP2 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
6
Sequence:
Chromosome: 5; NC_003076.8 (16807342..16810693, complement)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene ORMDL family protein Neighboring gene Transducin/WD40 repeat-like superfamily protein Neighboring gene ABL interactor-like protein 4 Neighboring gene regulatory particle non-ATPase 12B

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the BIP2 gene: The BIP2 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, rice, and frog.
  • Orthologs
NM_001344430.1
NM_123567.3
NM_180788.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
ATP binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ATPase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
heat shock protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
misfolded protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein binding involved in protein folding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
unfolded protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
cellular response to unfolded protein IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
chaperone cofactor-dependent protein refolding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
endoplasmic reticulum unfolded protein response IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
polar nucleus fusion IGI
Inferred from Genetic Interaction
more info
PubMed 
protein folding TAS
Traceable Author Statement
more info
PubMed 
protein refolding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
response to cadmium ion IEP
Inferred from Expression Pattern
more info
PubMed 
response to endoplasmic reticulum stress IEP
Inferred from Expression Pattern
more info
PubMed 
response to heat IDA
Inferred from Direct Assay
more info
PubMed 
response to unfolded protein IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ubiquitin-dependent ERAD pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
NOT Golgi apparatus RCA
inferred from Reviewed Computational Analysis
more info
PubMed 
cell wall IDA
Inferred from Direct Assay
more info
PubMed 
chloroplast ISM
Inferred from Sequence Model
more info
 
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
NOT cytosol RCA
inferred from Reviewed Computational Analysis
more info
PubMed 
endoplasmic reticulum IDA
Inferred from Direct Assay
more info
PubMed 
endoplasmic reticulum TAS
Traceable Author Statement
more info
 
endoplasmic reticulum chaperone complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
endoplasmic reticulum lumen IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
endoplasmic reticulum lumen TAS
Traceable Author Statement
more info
PubMed 
mediator complex IDA
Inferred from Direct Assay
more info
PubMed 
membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleolus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
plasmodesma IDA
Inferred from Direct Assay
more info
PubMed 
plastid HDA PubMed 
secretory vesicle HDA PubMed 
vacuolar membrane IDA
Inferred from Direct Assay
more info
PubMed 
vacuole IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
Heat shock protein 70 (Hsp 70) family protein
NP_199017.2
  • luminal binding protein (BIP); FUNCTIONS IN: ATP binding; INVOLVED IN: protein folding, response to cadmium ion, response to heat, polar nucleus fusion, response to endoplasmic reticulum stress; LOCATED IN: in 8 components; EXPRESSED IN: 7 plant structures; EXPRESSED DURING: seedling growth, seed development stages; CONTAINS InterPro DOMAIN/s: Heat shock protein 70, conserved site (InterPro:IPR018181), Heat shock protein Hsp70 (InterPro:IPR001023), Heat shock protein 70 (InterPro:IPR013126); BEST Arabidopsis thaliana protein match is: heat shock protein 70 (Hsp 70) family protein (TAIR:AT5G28540.1); Has 34912 Blast hits to 34423 proteins in 4667 species: Archae - 159; Bacteria - 17150; Metazoa - 3676; Fungi - 1797; Plants - 1301; Viruses - 340; Other Eukaryotes - 10489 (source: NCBI BLink).
NP_851119.1
  • BIP2; FUNCTIONS IN: ATP binding; INVOLVED IN: protein folding, response to cadmium ion, response to heat, polar nucleus fusion, response to endoplasmic reticulum stress; LOCATED IN: in 8 components; EXPRESSED IN: 8 plant structures; EXPRESSED DURING: seedling growth, seed development stages; CONTAINS InterPro DOMAIN/s: Heat shock protein 70, conserved site (InterPro:IPR018181), Heat shock protein Hsp70 (InterPro:IPR001023), Heat shock protein 70 (InterPro:IPR013126); BEST Arabidopsis thaliana protein match is: heat shock protein 70 (Hsp 70) family protein (TAIR:AT5G28540.1); Has 36681 Blast hits to 36078 proteins in 4871 species: Archae - 169; Bacteria - 17752; Metazoa - 3980; Fungi - 1822; Plants - 1284; Viruses - 342; Other Eukaryotes - 11332 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    16807342..16810693 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_180788.3NP_851119.1  Heat shock protein 70 (Hsp 70) family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_851119.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q39043
    UniProtKB/TrEMBL
    A0A178UG43
    Conserved Domains (2) summary
    cd10241
    Location:35409
    HSPA5-like_NBD; Nucleotide-binding domain of human HSPA5 and similar proteins
    PTZ00009
    Location:35654
    PTZ00009; heat shock 70 kDa protein; Provisional
  2. NM_001344430.1NP_001331824.1  Heat shock protein 70 (Hsp 70) family protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8BF32
  3. NM_123567.3NP_199017.2  Heat shock protein 70 (Hsp 70) family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_199017.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    F4K007
    Conserved Domains (2) summary
    cd10241
    Location:35409
    HSPA5-like_NBD; Nucleotide-binding domain of human HSPA5 and similar proteins
    PTZ00009
    Location:35599
    PTZ00009; heat shock 70 kDa protein; Provisional
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