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BIP2 Heat shock protein 70 (Hsp 70) family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 834207, updated on 12-Aug-2018

Summary

Gene symbol
BIP2
Gene description
Heat shock protein 70 (Hsp 70) family protein
Primary source
Araport:AT5G42020
Locus tag
AT5G42020
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
BIP; luminal binding protein; MJC20.12; MJC20_12
Summary
Luminal binding protein (BiP2) involved in polar nuclei fusion during proliferation of endosperm nuclei.

Genomic context

See BIP2 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
6
Sequence:
Chromosome: 5; NC_003076.8 (16807342..16810693, complement)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene ORMDL family protein Neighboring gene Transducin/WD40 repeat-like superfamily protein Neighboring gene ABL interactor-like protein 4 Neighboring gene regulatory particle non-ATPase 12B

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

  • Protein export, organism-specific biosystem (from KEGG)
    Protein export, organism-specific biosystemThe protein export is the active transport of proteins from the cytoplasm to the exterior of the cell, or to the periplasmic compartment in Gram-negative bacteria. The sec dependent pathway is the ge...
  • Protein export, conserved biosystem (from KEGG)
    Protein export, conserved biosystemThe protein export is the active transport of proteins from the cytoplasm to the exterior of the cell, or to the periplasmic compartment in Gram-negative bacteria. The sec dependent pathway is the ge...
  • Protein processing in endoplasmic reticulum, organism-specific biosystem (from KEGG)
    Protein processing in endoplasmic reticulum, organism-specific biosystemThe endoplasmic reticulum (ER) is a subcellular organelle where proteins are folded with the help of lumenal chaperones. Newly synthesized peptides enter the ER via the sec61 pore and are glycosylate...
  • Protein processing in endoplasmic reticulum, conserved biosystem (from KEGG)
    Protein processing in endoplasmic reticulum, conserved biosystemThe endoplasmic reticulum (ER) is a subcellular organelle where proteins are folded with the help of lumenal chaperones. Newly synthesized peptides enter the ER via the sec61 pore and are glycosylate...

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

NM_001344430.1
NM_123567.3
NM_180788.3

Gene Ontology Provided by TAIR

Process Evidence Code Pubs
polar nucleus fusion IGI
Inferred from Genetic Interaction
more info
PubMed 
protein folding ISS
Inferred from Sequence or Structural Similarity
more info
 
protein folding TAS
Traceable Author Statement
more info
PubMed 
response to cadmium ion IEP
Inferred from Expression Pattern
more info
PubMed 
response to cytokinin IDA
Inferred from Direct Assay
more info
PubMed 
response to endoplasmic reticulum stress IEP
Inferred from Expression Pattern
more info
PubMed 
response to heat IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
NOT Golgi apparatus RCA
inferred from Reviewed Computational Analysis
more info
PubMed 
cell wall IDA
Inferred from Direct Assay
more info
PubMed 
chloroplast ISM
Inferred from Sequence Model
more info
 
NOT cytosol RCA
inferred from Reviewed Computational Analysis
more info
PubMed 
endoplasmic reticulum IDA
Inferred from Direct Assay
more info
PubMed 
endoplasmic reticulum TAS
Traceable Author Statement
more info
 
endoplasmic reticulum lumen TAS
Traceable Author Statement
more info
PubMed 
mediator complex IDA
Inferred from Direct Assay
more info
PubMed 
membrane IDA
Inferred from Direct Assay
more info
PubMed 
nucleolus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
plasmodesma IDA
Inferred from Direct Assay
more info
PubMed 
vacuolar membrane IDA
Inferred from Direct Assay
more info
PubMed 
vacuole IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
Heat shock protein 70 (Hsp 70) family protein
NP_199017.2
  • luminal binding protein (BIP); FUNCTIONS IN: ATP binding; INVOLVED IN: protein folding, response to cadmium ion, response to heat, polar nucleus fusion, response to endoplasmic reticulum stress; LOCATED IN: in 8 components; EXPRESSED IN: 7 plant structures; EXPRESSED DURING: seedling growth, seed development stages; CONTAINS InterPro DOMAIN/s: Heat shock protein 70, conserved site (InterPro:IPR018181), Heat shock protein Hsp70 (InterPro:IPR001023), Heat shock protein 70 (InterPro:IPR013126); BEST Arabidopsis thaliana protein match is: heat shock protein 70 (Hsp 70) family protein (TAIR:AT5G28540.1); Has 34912 Blast hits to 34423 proteins in 4667 species: Archae - 159; Bacteria - 17150; Metazoa - 3676; Fungi - 1797; Plants - 1301; Viruses - 340; Other Eukaryotes - 10489 (source: NCBI BLink).
NP_851119.1
  • BIP2; FUNCTIONS IN: ATP binding; INVOLVED IN: protein folding, response to cadmium ion, response to heat, polar nucleus fusion, response to endoplasmic reticulum stress; LOCATED IN: in 8 components; EXPRESSED IN: 8 plant structures; EXPRESSED DURING: seedling growth, seed development stages; CONTAINS InterPro DOMAIN/s: Heat shock protein 70, conserved site (InterPro:IPR018181), Heat shock protein Hsp70 (InterPro:IPR001023), Heat shock protein 70 (InterPro:IPR013126); BEST Arabidopsis thaliana protein match is: heat shock protein 70 (Hsp 70) family protein (TAIR:AT5G28540.1); Has 36681 Blast hits to 36078 proteins in 4871 species: Archae - 169; Bacteria - 17752; Metazoa - 3980; Fungi - 1822; Plants - 1284; Viruses - 342; Other Eukaryotes - 11332 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    16807342..16810693 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_180788.3NP_851119.1  Heat shock protein 70 (Hsp 70) family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_851119.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q39043
    UniProtKB/TrEMBL
    A0A178UG43
    Conserved Domains (2) summary
    cd10241
    Location:35409
    HSPA5-like_NBD; Nucleotide-binding domain of human HSPA5 and similar proteins
    PTZ00009
    Location:35654
    PTZ00009; heat shock 70 kDa protein; Provisional
  2. NM_001344430.1NP_001331824.1  Heat shock protein 70 (Hsp 70) family protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8BF32
  3. NM_123567.3NP_199017.2  Heat shock protein 70 (Hsp 70) family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_199017.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    F4K007
    Conserved Domains (2) summary
    cd10241
    Location:35409
    HSPA5-like_NBD; Nucleotide-binding domain of human HSPA5 and similar proteins
    PTZ00009
    Location:35599
    PTZ00009; heat shock 70 kDa protein; Provisional
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