U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Cstf2t cleavage stimulation factor, 3' pre-RNA subunit 2, tau [ Mus musculus (house mouse) ]

Gene ID: 83410, updated on 27-Nov-2024

Summary

Official Symbol
Cstf2tprovided by MGI
Official Full Name
cleavage stimulation factor, 3' pre-RNA subunit 2, tauprovided by MGI
Primary source
MGI:MGI:1932622
See related
Ensembl:ENSMUSG00000053536 AllianceGenome:MGI:1932622
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
64kDa; tCstF-64; tauCstF-64
Summary
Enables RNA binding activity. Predicted to act upstream of or within mRNA 3'-end processing. Predicted to be located in nucleoplasm. Predicted to be part of mRNA cleavage and polyadenylation specificity factor complex. Is expressed in brain and spinal cord. Orthologous to human CSTF2T (cleavage stimulation factor subunit 2 tau variant). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Cstf2t in Genome Data Viewer
Location:
19 C1; 19 25.94 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (31060241..31063992)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (31082841..31086592)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene protein kinase, cGMP-dependent, type I Neighboring gene ATPase, H+ transporting, lysosomal V1 subunit E1 pseudogene Neighboring gene ubiquitin-like 5 pseudogene Neighboring gene STARR-seq mESC enhancer starr_45914 Neighboring gene STARR-positive B cell enhancer ABC_E7644 Neighboring gene CapStarr-seq enhancer MGSCv37_chr19:31157349-31157532 Neighboring gene STARR-seq mESC enhancer starr_45917 Neighboring gene STARR-seq mESC enhancer starr_45919 Neighboring gene STARR-seq mESC enhancer starr_45920 Neighboring gene 60S ribosomal protein L18 pseudogene Neighboring gene RIKEN cDNA 8430431K14 gene

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Targeted (1)  1 citation

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within mRNA 3'-end processing TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
part_of mRNA cleavage and polyadenylation specificity factor complex IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
cleavage stimulation factor subunit 2 tau variant
Names
CF-1 64 kDa subunit, tau
CSTF 64 kDa subunit, tau
cleavage stimulation factor 64 kDa subunit, tau
cleavage stimulation factor subunit 2 tau
cleavage stimulation factor, 3' pre-RNA subunit 2, 64 kDa, tau

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_031249.2NP_112539.2  cleavage stimulation factor subunit 2 tau variant

    See identical proteins and their annotated locations for NP_112539.2

    Status: VALIDATED

    Source sequence(s)
    AK082910, BY637182, CJ182579
    Consensus CDS
    CCDS37958.1
    UniProtKB/Swiss-Prot
    Q6A016, Q8BHH7, Q8C3W7, Q8C7E9, Q8R2Y1, Q9EPU3
    Related
    ENSMUSP00000093831.4, ENSMUST00000066039.8
    Conserved Domains (4) summary
    COG0724
    Location:16109
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12671
    Location:1892
    RRM_CSTF2_CSTF2T; RNA recognition motif in cleavage stimulation factor subunit 2 (CSTF2), cleavage stimulation factor subunit 2 tau variant (CSTF2T) and similar proteins
    pfam14304
    Location:588628
    CSTF_C; Transcription termination and cleavage factor C-terminal
    pfam14327
    Location:113191
    CSTF2_hinge; Hinge domain of cleavage stimulation factor subunit 2

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    31060241..31063992
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)