MOS11 Protein MODIFIER OF SNC1 11 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: MOS11
Official Full Name: Protein MODIFIER OF SNC1 11
Primary source: TAIR:AT5G02770
Locus tag: AT5G02770
See related: Araport:AT5G02770
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: 11; F9G14.80; F9G14_80; modifier of snc1
Summary: Encodes a conserved eukaryotic protein with homology to the human RNA binding protein CIP29 that localizes to the nucleus. Mutants accumulate more poly(A) mRNAs in the nucleus, likely resulting from reduced mRNA export activity.
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Genomic context

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See MOS11 in Genome Data Viewer

Location:: chromosome: 5

Exon count:: 6

Sequence:: Chromosome: 5; NC_003076.8 (627034..629280, complement)

Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Arabidopsis mRNA export factor MOS11: molecular interactions and role in abiotic stress responses.
Title: Arabidopsis mRNA export factor MOS11: molecular interactions and role in abiotic stress responses.
Arabidopsis TEX1 and MOS11 are involved in distinct steps of the biogenesis of mRNAs and small RNAs, and that they interact regarding some aspects, but act independently in others.
Title: The Arabidopsis THO/TREX component TEX1 functionally interacts with MOS11 and modulates mRNA export and alternative splicing events.
MOS11 (At5g02770) is a new component for mRNA export.
Title: MOS11: a new component in the mRNA export pathway.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_120355.3

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within poly(A)+ mRNA export from nucleus	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: Protein MODIFIER OF SNC1 11

NP_195897.1

unknown protein; Has 469 Blast hits to 336 proteins in 126 species: Archae - 0; Bacteria - 54; Metazoa - 249; Fungi - 22; Plants - 47; Viruses - 0; Other Eukaryotes - 97 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003076.8 Reference assembly

Range

627034..629280 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_120355.3 → NP_195897.1 Protein MODIFIER OF SNC1 11 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_195897.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9LZ08

UniProtKB/TrEMBL

A0A5S9Y0T3, A0A654FXQ3

Conserved Domains (2) summary

PTZ00121
Location:45 → 213

PTZ00121; MAEBL; Provisional

pfam18592
Location:78 → 111

Tho1_MOS11_C; Tho1/MOS11 C-terminal domain