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N7525_006405 isopenicillin N synthase ips/PcbC-Penicillium chrysogenum [ Penicillium rubens ]

Gene ID: 8310374, updated on 1-Feb-2024

Summary

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Gene symbol
N7525_006405
Gene description
isopenicillin N synthase ips/PcbC-Penicillium chrysogenum
Locus tag
N7525_006405
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Penicillium rubens (strain: IBT 27055, culture-collection: IBT:27055)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium; Penicillium chrysogenum species complex
Old locus tag
Pc21g21380
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Genomic context

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Location:
chromosome: Unknown
Exon count:
1

NW_026890601.1Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene AMP-dependent synthetase/ligase Neighboring gene acyl-coenzyme A:isopenicillin N acyltransferase (acyltransferase) AAT/PenDE-Penicillium chrysogenum Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_026890601.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The regulatory factor PcRFX1 controls the expression of the three genes of β-lactam biosynthesis in Penicillium chrysogenum. Domínguez-Santos R, et al. Fungal Genet Biol, 2012 Nov. PMID 22960281
  2. Reduced function of a phenylacetate-oxidizing cytochrome p450 caused strong genetic improvement in early phylogeny of penicillin-producing strains. Rodríguez-Sáiz M, et al. J Bacteriol, 2001 Oct. PMID 11544206, Free PMC Article
  3. Molecular analysis of a Penicillium chrysogenum GATA factor encoding gene (sreP) exhibiting significant homology to the Ustilago maydis urbs1 gene. Haas H, et al. Gene, 1997 Jan 3. PMID 9016950
  4. Cloning and characterization of the acyl-coenzyme A: 6-aminopenicillanic-acid-acyltransferase gene of Penicillium chrysogenum. Barredo JL, et al. Gene, 1989 Nov 30. PMID 2555269
  5. Cloning, sequence analysis and transcriptional study of the isopenicillin N synthase of Penicillium chrysogenum AS-P-78. Barredo JL, et al. Mol Gen Genet, 1989 Mar. PMID 2499766

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. PcRFX1 controls penicillin biosynthesis through the regulation of the pcbAB, pcbC and penDE transcription.
    Title: The regulatory factor PcRFX1 controls the expression of the three genes of β-lactam biosynthesis in Penicillium chrysogenum.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 2-oxoglutarate-dependent dioxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
isopenicillin N synthase ips/PcbC-Penicillium chrysogenum
XP_002569113.2
  • 2OG-Fe(II) oxygenase superfamily; non-haem dioxygenase in morphine synthesis N-terminal

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NW_026890601.1 Reference assembly

    Range
    563401..564396
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002569067.2 → XP_002569113.2  isopenicillin N synthase ips/PcbC-Penicillium chrysogenum [Penicillium rubens]

    Status: PROVISIONAL

Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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