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CIPK2 CBL-interacting protein kinase 2 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 830598, updated on 13-May-2026
Official Symbol
CIPK2
Official Full Name
CBL-interacting protein kinase 2
Primary source
TAIR:AT5G07070
Locus tag
AT5G07070
See related
Araport:AT5G07070
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
CBL-interacting protein kinase 2; CBL-INTERACTING PROTEIN KINASE 2; SNF1-RELATED PROTEIN KINASE 3.2; SnRK3.2; T28J14.10; T28J14_10
Summary
Encodes CBL-interacting protein kinase 2 (CIPK2).
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Location:
chromosome: 5
Exon count:
1
Sequence:
Chromosome: 5; NC_003076.8 (2196428..2198539, complement)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene nodulin MtN21 /EamA-like transporter family protein Neighboring gene CCCH-type zinc fingerfamily protein with RNA-binding domain-containing protein Neighboring gene ncRNA Neighboring gene HXXXD-type acyl-transferase family protein Neighboring gene Ribosomal protein S4 (RPS4A) family protein

Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Novel protein kinases associated with calcineurin B-like calcium sensors in Arabidopsis. Shi J, et al. Plant Cell, 1999 Dec. PMID 10590166, Free PMC Article
  2. Interaction specificity of Arabidopsis calcineurin B-like calcium sensors and their target kinases. Kim KN, et al. Plant Physiol, 2000 Dec. PMID 11115898, Free PMC Article
  3. Phosphorylation of calcineurin B-like (CBL) calcium sensor proteins by their CBL-interacting protein kinases (CIPKs) is required for full activity of CBL-CIPK complexes toward their target proteins. Hashimoto K, et al. J Biol Chem, 2012 Mar 9. PMID 22253446, Free PMC Article
  4. The NAF domain defines a novel protein-protein interaction module conserved in Ca2+-regulated kinases. Albrecht V, et al. EMBO J, 2001 Mar 1. PMID 11230129, Free PMC Article
  5. Comprehensive structural, interaction and expression analysis of CBL and CIPK complement during abiotic stresses and development in rice. Kanwar P, et al. Cell Calcium, 2014 Aug. PMID 24970010

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

NM_120789.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
Preferred Names
CBL-interacting protein kinase 2
NP_196324.1
  • CBL-interacting protein kinase 2 (CIPK2); FUNCTIONS IN: protein serine/threonine kinase activity, protein kinase activity, kinase activity, ATP binding; INVOLVED IN: signal transduction, protein amino acid phosphorylation; LOCATED IN: cellular_component unknown; EXPRESSED IN: stem, leaf whorl, root, flower; EXPRESSED DURING: petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Serine/threonine-protein kinase domain (InterPro:IPR002290), NAF/FISL domain (InterPro:IPR018451), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), NAF domain (InterPro:IPR004041), CBL-interacting protein kinase (InterPro:IPR020660), Protein kinase, catalytic domain (InterPro:IPR000719), Calcium/calmodulin-dependent protein kinase-like (InterPro:IPR020636); BEST Arabidopsis thaliana protein match is: SOS3-interacting protein 1 (TAIR:AT5G58380.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    2196428..2198539 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_120789.3 → NP_196324.1  CBL-interacting protein kinase 2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_196324.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9LKD0, Q9LYQ8
    UniProtKB/TrEMBL
    A0A178URC7, A0A5S9Y235
    Conserved Domains (2) summary
    cd12195
    Location:315 → 428
    CIPK_C; C-terminal regulatory domain of Calcineurin B-Like (CBL)-interacting protein kinases
    cl21453
    Location:11 → 265
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9LYQ8.1

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