CPSRP54 chloroplast signal recognition particle 54 kDa subunit [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: CPSRP54
Official Full Name: chloroplast signal recognition particle 54 kDa subunit
Primary source: TAIR:AT5G03940
Locus tag: AT5G03940
See related: Araport:AT5G03940
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: 54 CHLOROPLAST PROTEIN; 54CP; chloroplast signal recognition particle 54 kDa subunit; F8F6.150; F8F6_150; FFC; FIFTY-FOUR CHLOROPLAST HOMOLOGUE; SIGNAL RECOGNITION PARTICLE 54 KDA SUBUNIT; SIGNAL RECOGNITION PARTICLE 54 KDA SUBUNIT CHLOROPLAST PROTEIN; SRP54CP
Summary: mutant has Yellow first leaves; Chloroplast Signal Recognition Particle Subunit
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Genomic context

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See CPSRP54 in Genome Data Viewer

Location:: chromosome: 5

Exon count:: 14

Sequence:: Chromosome: 5; NC_003076.8 (1060106..1063425, complement)

Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

results support the conclusion that substrate binding to the chloroplast SRP is modulated by protein structural dynamics in which a major role of cpSRP54 is to improve substrate binding efficiency to the cpSRP.
Title: Regulation of Structural Dynamics within a Signal Recognition Particle Promotes Binding of Protein Targeting Substrates.
cbd is a recessive mutant in the gene cpSRP54 encoding the 54 kDa subunit of the chloroplast signal recognition particle. Relative to wild type, expression increased in carotenoid and abscisic acid catabolic genes.
Title: Arabidopsis cpSRP54 regulates carotenoid accumulation in Arabidopsis and Brassica napus.
The authors report the crystal structure of the chloroplast signal recognition particle (cpSRP) core from Arabidopsis thaliana, with the cpSRP54 tail comprising an arginine-rich motif bound to the second chromodomain of cpSRP43.
Title: Chromodomains read the arginine code of post-translational targeting.
cpSRP54 deletion led to a change in light-harvesting complex composition, an increase of PsbS, a decreased photosystem I/II ratio, and, in young leaves, to up-regulation of thylakoid proteases and stromal chaperones, including ClpC
Title: Quantitative proteomics of a chloroplast SRP54 sorting mutant and its genetic interactions with CLPC1 in Arabidopsis.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_120476.5

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables signal sequence binding	IDA Inferred from Direct Assay more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within protein import into chloroplast thylakoid membrane	IDA Inferred from Direct Assay more info

Component	Evidence Code	Pubs
located_in chloroplast	HDA more info	PubMed
located_in chloroplast	ISM Inferred from Sequence Model more info
located_in chloroplast stroma	HDA more info	PubMed
located_in chloroplast stroma	IDA Inferred from Direct Assay more info
located_in plasma membrane	HDA more info	PubMed
part_of signal recognition particle, chloroplast targeting	IMP Inferred from Mutant Phenotype more info	PubMed

General protein information

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Preferred Names: chloroplast signal recognition particle 54 kDa subunit

NP_196014.1

chloroplast signal recognition particle 54 kDa subunit (CPSRP54); FUNCTIONS IN: 7S RNA binding, protein binding, mRNA binding, GTP binding, signal sequence binding; INVOLVED IN: protein import into chloroplast thylakoid membrane, SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition; LOCATED IN: chloroplast stroma, chloroplast, signal recognition particle, chloroplast targeting, signal recognition particle, endoplasmic reticulum targeting; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), Signal recognition particle, SRP (InterPro:IPR004780), Signal recognition particle, SRP54 subunit, helical bundle (InterPro:IPR013822), Signal recognition particle, SRP54 subunit, M-domain (InterPro:IPR004125), Signal recognition particle, SRP54 subunit, GTPase (InterPro:IPR000897); BEST Arabidopsis thaliana protein match is: Signal recognition particle, SRP54 subunit protein (TAIR:AT1G48900.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003076.8 Reference assembly

Range

1060106..1063425 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_120476.5 → NP_196014.1 chloroplast signal recognition particle 54 kDa subunit [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_196014.1

Status: REVIEWED

UniProtKB/Swiss-Prot

O82570, P37107

UniProtKB/TrEMBL

A0A178UD49, A0A5S9Y3D9, A0A7G2F4W1

Conserved Domains (1) summary

PRK10867
Location:77 → 507

PRK10867; signal recognition particle protein; Provisional