RR10 response regulator 10 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Gene symbol: RR10
Gene description: response regulator 10
Primary source: Araport:AT4G31920
Locus tag: AT4G31920
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ARR10; F11C18.3; response regulator 10
Summary: Encodes an Arabidopsis response regulator (ARR) protein that acts in concert with other type-B ARRs in the cytokinin signaling pathway. Also involved in cytokinin-dependent inhibition of hypocotyl elongation and cytokinin-dependent greening and shooting in tissue culture.
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Genomic context

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See RR10 in Genome Data Viewer

Location:: chromosome: 4

Exon count:: 6

Sequence:: Chromosome: 4; NC_003075.7 (15444053..15447042, complement)

Chromosome 4 - NC_003075.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The expression signals of AG were detected in the initiating carpel primordia and regenerating carpels, and co-localized with those of two Type-B ARABIDOPSIS RESPONSE REGULATORs (ARRs), ARR1 and ARR10.
Title: Type-B ARRs Control Carpel Regeneration Through Mediating AGAMOUS Expression in Arabidopsis.
The role of ARR10 in regulating the cytokinin response and growth in Arabidopsis
Title: Cytokinin induces genome-wide binding of the type-B response regulator ARR10 to regulate growth and development in Arabidopsis.
An arr1,10,12 triple mutant had more drought tolerance due to enhanced cell membrane integrity, anthocyanin synthesis, and abscissic acid hypersensitivity, and reduced stomatal aperture. Dehydration and ABA repressed all 3 genes.
Title: Arabidopsis type B cytokinin response regulators ARR1, ARR10, and ARR12 negatively regulate plant responses to drought.
Results support a model in which cytokinin regulates a wide array of downstream responses through the action of a multistep phosphorelay that culminates in transcriptional regulation by ARR1, ARR10, and ARR12.
Title: Type B response regulators of Arabidopsis play key roles in cytokinin signaling and plant development.
The results of this study suggested that ARR1, ARR10 and ARR12 together play essential (or general) roles in cytokinin signal transduction.
Title: Three type-B response regulators, ARR1, ARR10 and ARR12, play essential but redundant roles in cytokinin signal transduction throughout the life cycle of Arabidopsis thaliana.
ARR10 and ARR12play pivotal roles in the histidine kinase-dependent phosphorelay signaling in response to cytokinin in roots.
Title: Type-B ARR transcription factors, ARR10 and ARR12, are implicated in cytokinin-mediated regulation of protoxylem differentiation in roots of Arabidopsis thaliana.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_119343.4

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity	IDA Inferred from Direct Assay more info	PubMed
enables DNA-binding transcription factor activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables phosphorelay response regulator activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within callus formation	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within cellular response to cytokinin stimulus	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within cytokinin-activated signaling pathway	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within cytokinin-activated signaling pathway	TAS Traceable Author Statement more info	PubMed
acts_upstream_of_or_within maintenance of shoot apical meristem identity	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within primary root development	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within regulation of anthocyanin metabolic process	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within regulation of chlorophyll biosynthetic process	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within regulation of cytokinin-activated signaling pathway	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of cytokinin-activated signaling pathway	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within regulation of root meristem growth	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of root meristem growth	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within regulation of seed growth	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within response to cytokinin	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within response to water deprivation	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within response to water deprivation	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within root development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within shoot system development	IGI Inferred from Genetic Interaction more info	PubMed

Component	Evidence Code	Pubs
located_in chloroplast	ISM Inferred from Sequence Model more info
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: response regulator 10

NP_194920.1

response regulator 10 (RR10); CONTAINS InterPro DOMAIN/s: Response regulator, plant B-type (InterPro:IPR017053), Myb-like DNA-binding domain, SHAQKYF class (InterPro:IPR006447), CheY-like (InterPro:IPR011006), Homeodomain-like (InterPro:IPR009057), Myb, DNA-binding (InterPro:IPR014778), Signal transduction response regulator, receiver domain (InterPro:IPR001789), HTH transcriptional regulator, Myb-type, DNA-binding (InterPro:IPR017930), Homeodomain-related (InterPro:IPR012287); BEST Arabidopsis thaliana protein match is: response regulator 12 (TAIR:AT2G25180.1); Has 117582 Blast hits to 116317 proteins in 3081 species: Archae - 744; Bacteria - 104604; Metazoa - 49; Fungi - 620; Plants - 2843; Viruses - 4; Other Eukaryotes - 8718 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003075.7 Reference assembly

Range

15444053..15447042 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_119343.4 → NP_194920.1 response regulator 10 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_194920.1

Status: REVIEWED

UniProtKB/Swiss-Prot

O49397

UniProtKB/TrEMBL

A0A178V074, A0A384KXN7, A0A654FUR1, Q0WRZ4

Conserved Domains (2) summary

TIGR01557
Location:183 → 235

myb_SHAQKYF; myb-like DNA-binding domain, SHAQKYF class

cd17584
Location:19 → 133

REC_typeB_ARR-like; phosphoacceptor receiver (REC) domain of type B Arabidopsis response regulators (ARRs) and similar domains