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GrxC5 Glutaredoxin family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 828994, updated on 18-Sep-2024
Official Symbol
GrxC5
Official Full Name
Glutaredoxin family protein
Primary source
TAIR:AT4G28730
Locus tag
AT4G28730
See related
Araport:AT4G28730
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F16A16.160; F16A16_160; glutaredoxin C5
Summary
Encodes a glutaredoxin GrxC5. GrxC5 exists as two forms when expressed in Escherichia coli. The monomeric apoprotein possesses deglutathionylation activity mediating the recycling of plastidial methionine sulfoxide reductase B1 and peroxiredoxin IIE, whereas the dimeric holoprotein incorporates a [2Fe-2S] cluster.
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See GrxC5 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
4
Sequence:
Chromosome: 4; NC_003075.7 (14199043..14200903)

Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene pfkB-like carbohydrate kinase family protein Neighboring gene Myosin family protein with Dil domain-containing protein Neighboring gene Flavin-binding monooxygenase family protein Neighboring gene LOW PSII ACCUMULATION-like protein Neighboring gene uncharacterized protein Neighboring gene Photosystem I reaction centre subunit IV / PsaE protein

Genomic Sequence:
NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Arabidopsis chloroplastic glutaredoxin C5 as a model to explore molecular determinants for iron-sulfur cluster binding into glutaredoxins. Couturier J, et al. J Biol Chem, 2011 Aug 5. PMID 21632542, Free PMC Article
  2. Monothiol glutaredoxin-BolA interactions: redox control of Arabidopsis thaliana BolA2 and SufE1. Couturier J, et al. Mol Plant, 2014 Jan. PMID 24203231
  3. A proteomic strategy for global analysis of plant protein complexes. Aryal UK, et al. Plant Cell, 2014 Oct. PMID 25293756, Free PMC Article
  4. Sorting signals, N-terminal modifications and abundance of the chloroplast proteome. Zybailov B, et al. PLoS One, 2008 Apr 23. PMID 18431481, Free PMC Article
  5. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

NM_001341931.1
NM_119017.5

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables glutathione-disulfide reductase (NADPH) activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within iron-sulfur cluster assembly IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast HDA PubMed 
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
Preferred Names
Glutaredoxin family protein
NP_194602.2
  • Glutaredoxin family protein; FUNCTIONS IN: electron carrier activity, protein disulfide oxidoreductase activity; INVOLVED IN: cell redox homeostasis; LOCATED IN: chloroplast; CONTAINS InterPro DOMAIN/s: Thioredoxin fold (InterPro:IPR012335), Glutaredoxin (InterPro:IPR002109), Glutaredoxin subgroup (InterPro:IPR014025), Glutaredoxin, eukaryotic/virial (InterPro:IPR011899), Thioredoxin-like fold (InterPro:IPR012336); BEST Arabidopsis thaliana protein match is: Thioredoxin superfamily protein (TAIR:AT2G20270.1); Has 4412 Blast hits to 4405 proteins in 1169 species: Archae - 6; Bacteria - 1982; Metazoa - 422; Fungi - 333; Plants - 692; Viruses - 111; Other Eukaryotes - 866 (source: NCBI BLink).

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003075.7 Reference assembly

    Range
    14199043..14200903
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_119017.5 → NP_194602.2  Glutaredoxin family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_194602.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8GWS0, Q9SVU1
    UniProtKB/TrEMBL
    A0A178UXL4, A0A5S9XYX7
    Conserved Domains (1) summary
    cd03419
    Location:82 → 161
    GRX_GRXh_1_2_like; Glutaredoxin (GRX) family, GRX human class 1 and 2 (h_1_2)-like subfamily; composed of proteins similar to human GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, ...

  2. NM_001341931.1 → NP_001328515.1  Glutaredoxin family protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8B4W9
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8GWS0.1

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