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UGE2 UDP-D-glucose/UDP-D-galactose 4-epimerase 2 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 828492, updated on 19-Feb-2025
Official Symbol
UGE2
Official Full Name
UDP-D-glucose/UDP-D-galactose 4-epimerase 2
Primary source
TAIR:AT4G23920
Locus tag
AT4G23920
See related
Araport:AT4G23920
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATUGE2; T32A16.90; T32A16_90; UDP-D-glucose/UDP-D-galactose 4-epimerase 2; UDP-GLC 4-EPIMERASE 2
Summary
Encodes a protein with UDP-D-glucose 4-epimerase activity. Involved in growth and cell wall carbohydrate biosynthesis.
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See UGE2 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
9
Sequence:
Chromosome: 4; NC_003075.7 (12431097..12433912)

Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene tRNA-Ala Neighboring gene Late embryogenesis abundant (LEA) hydroxyproline-rich glycoprotein family Neighboring gene FtsH extracellular protease family

Genomic Sequence:
NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. UDP-glucose 4-epimerase isoforms UGE2 and UGE4 cooperate in providing UDP-galactose for cell wall biosynthesis and growth of Arabidopsis thaliana. Rösti J, et al. Plant Cell, 2007 May. PMID 17496119, Free PMC Article
  2. Distinct properties of the five UDP-D-glucose/UDP-D-galactose 4-epimerase isoforms of Arabidopsis thaliana. Barber C, et al. J Biol Chem, 2006 Jun 23. PMID 16644739
  3. Identification of Open Stomata1-Interacting Proteins Reveals Interactions with Sucrose Non-fermenting1-Related Protein Kinases2 and with Type 2A Protein Phosphatases That Function in Abscisic Acid Responses. Waadt R, et al. Plant Physiol, 2015 Sep. PMID 26175513, Free PMC Article
  4. Identification of multiple salicylic acid-binding proteins using two high throughput screens. Manohar M, et al. Front Plant Sci, 2014. PMID 25628632, Free PMC Article
  5. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. UGE2 and UGE4 influence growth and cell wall carbohydrate biosynthesis throughout the plant, UGE3 is specialized for pollen development, and UGE1 and UGE5 might act in stress situations.
    Title: UDP-glucose 4-epimerase isoforms UGE2 and UGE4 cooperate in providing UDP-galactose for cell wall biosynthesis and growth of Arabidopsis thaliana.
Submit: New GeneRIF Correction
Products Interactant Other Gene Complex Source Pubs Description
NM_118524.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables UDP-glucose 4-epimerase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables UDP-glucose 4-epimerase activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
enables protein dimerization activity IPI
Inferred from Physical Interaction
more info
 PubMed 
enables salicylic acid binding HDA PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within cell wall biogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 
Preferred Names
UDP-D-glucose/UDP-D-galactose 4-epimerase 2
NP_194123.1
  • UDP-D-glucose/UDP-D-galactose 4-epimerase 2 (UGE2); CONTAINS InterPro DOMAIN/s: NAD-dependent epimerase/dehydratase (InterPro:IPR001509), NAD(P)-binding domain (InterPro:IPR016040), UDP-glucose 4-epimerase (InterPro:IPR005886); BEST Arabidopsis thaliana protein match is: UDP-D-glucose/UDP-D-galactose 4-epimerase 5 (TAIR:AT4G10960.1); Has 45788 Blast hits to 45762 proteins in 3004 species: Archae - 838; Bacteria - 27545; Metazoa - 690; Fungi - 619; Plants - 1224; Viruses - 37; Other Eukaryotes - 14835 (source: NCBI BLink).

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003075.7 Reference assembly

    Range
    12431097..12433912
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_118524.3 → NP_194123.1  UDP-D-glucose/UDP-D-galactose 4-epimerase 2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_194123.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q541V9, Q8LFW1, Q9T0A7
    UniProtKB/TrEMBL
    A0A178V4G0, A0A5S9XW54
    Conserved Domains (2) summary
    PLN02240
    Location:1 → 338
    PLN02240; UDP-glucose 4-epimerase
    TIGR01179
    Location:5 → 337
    galE; UDP-glucose-4-epimerase GalE
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9T0A7.1

Gene LinkOut

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